PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9444664-1 1997 Since some antisecretory drugs such as cimetidine and ranitidine, interfere with ethanol metabolism by inhibition of hepatic and/or gastric alcohol dehydrogenase, we investigated the effect of lansoprazole, a new protonic pump inhibitor, on gastric and hepatic alcohol dehydrogenase activity. Ranitidine 54-64 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide Homo sapiens 132-161 1727201-2 1992 OBJECTIVE: To determine whether the H2-receptor antagonist, ranitidine, which is a potent inhibitor of gastric alcohol dehydrogenase activity in vitro, increases the bioavailability of orally administered ethanol (0.3 g/kg of body weight) and to compare the resulting blood alcohol concentrations with those of two other H2-antagonists, cimetidine and famotidine, the latter of which does not inhibit gastric alcohol dehydrogenase. Ranitidine 60-70 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide Homo sapiens 103-132 1727201-2 1992 OBJECTIVE: To determine whether the H2-receptor antagonist, ranitidine, which is a potent inhibitor of gastric alcohol dehydrogenase activity in vitro, increases the bioavailability of orally administered ethanol (0.3 g/kg of body weight) and to compare the resulting blood alcohol concentrations with those of two other H2-antagonists, cimetidine and famotidine, the latter of which does not inhibit gastric alcohol dehydrogenase. Ranitidine 60-70 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide Homo sapiens 401-430