PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23582449-3 2013 Experiments with electrically stimulated rat vas deference contractions induced by the PRE-084, an agonist of sigma-1 receptor, showed that (4R,5S)- and (4R,5R)-2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamides with an R-configuration at the C-4 chiral centre in the 2-pyrrolidone ring were more effective positive allosteric modulators of sigma-1 receptor than were their optical antipodes. 2-pyrrolidone 271-284 sigma non-opioid intracellular receptor 1 Rattus norvegicus 110-126