PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23796861-1 2013 PURPOSE: To characterize epileptic spasms (ES) occurring after the age of two years in patients with tuberous sclerosis complex (TSC), particularly treatment response to vigabatrin (VGB), which is extremely effective for infantile spasms (IS) in TSC. Vigabatrin 170-180 TSC complex subunit 1 Homo sapiens 129-132 32563542-8 2020 Multicenter, prospective studies are ongoing to identify if presymptomatic treatment with vigabatrin in patients with TSC can improve outcomes, including autism. Vigabatrin 90-100 TSC complex subunit 1 Homo sapiens 118-121 29881807-2 2018 Epilepsy occurs in 80%-90% of affected individuals during their lifetime, and up to one-third of children with TSC will develop epileptic (infantile) spasms, for which vigabatrin has been shown to be particularly effective. Vigabatrin 168-178 TSC complex subunit 1 Homo sapiens 111-114 23796861-1 2013 PURPOSE: To characterize epileptic spasms (ES) occurring after the age of two years in patients with tuberous sclerosis complex (TSC), particularly treatment response to vigabatrin (VGB), which is extremely effective for infantile spasms (IS) in TSC. Vigabatrin 170-180 TSC complex subunit 1 Homo sapiens 246-249 18345974-7 2008 Vigabatrin has proved to be effective against infantile spasms due to TSC. Vigabatrin 0-10 TSC complex subunit 1 Homo sapiens 70-73