PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19477943-1 2009 The Cyp27b1 enzyme (25-hydroxyvitamin D-1alpha-hydroxylase) that converts 25-hydroxyvitamin D into the active metabolite, 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)], is expressed in kidney but also in other cell types such as chondrocytes. 25-hydroxyvitamin D 20-39 cytochrome P450, family 27, subfamily b, polypeptide 1 Mus musculus 4-11 21482732-12 2011 Finally, ex vivo treatment of WT placentas with the substrate for Cyp27b1, 25-hydroxyvitamin D(3), suppressed LPS-induced expression of IL-6 and the chemokine Ccl11. 25-hydroxyvitamin D 75-94 cytochrome P450, family 27, subfamily b, polypeptide 1 Mus musculus 66-73 19944755-3 2010 Using Cyp27b1 knockout cells and a 1alpha-hydroxylase-specific inhibitor we provide in four cellular systems, primary mouse kidney, skin, prostate cells and human MCF-7 breast cancer cells, evidence that 25-hydroxyvitamin D(3) has direct gene regulatory properties. 25-hydroxyvitamin D 204-223 cytochrome P450, family 27, subfamily b, polypeptide 1 Mus musculus 6-13 12006701-3 2002 The final, critical step in this biosynthesis is conversion from 25-hydroxyvitamin D(3) to 1alpha,25(OH)(2)D(3) by the enzyme 25-hydroxyvitamin D(3) 1alpha-hydroxylase(CYP27B1)[1alpha(OH)ase]. 25-hydroxyvitamin D 65-84 cytochrome P450, family 27, subfamily b, polypeptide 1 Mus musculus 177-190 11149489-1 2001 The murine homologue of the 25-hydroxyvitamin D [25(OH)D] 1alpha-hydroxylase gene [1alpha(OH)ase; Cyp27bl], which is mutated in humans with vitamin D-dependent rickets type I (VDDR-I; also known as pseudovitamin D-deficiency rickets [PDDR]) was cloned and characterized. 25-hydroxyvitamin D 28-47 cytochrome P450, family 27, subfamily b, polypeptide 1 Mus musculus 83-96 22968766-8 2013 Recent identification of CYP27B1 bioactivity in skeletal muscle cells and in regenerating adult mouse muscle lends support to the direct action of both 25-hydroxyvitamin D and 1,25(OH)(2)D in muscle. 25-hydroxyvitamin D 152-171 cytochrome P450, family 27, subfamily b, polypeptide 1 Mus musculus 25-32