PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24596595-1 2014 Genome-wide association studies (GWAS) have identified common polymorphisms in or near GC, CYP2R1, CYP24A1, and NADSYN1/DHCR7 genes to be associated with circulating levels of 25-hydroxyvitamin D [25(OH)D] in European populations. 25-hydroxyvitamin D 176-195 7-dehydrocholesterol reductase Homo sapiens 120-125 23734184-3 2013 METHODOLOGY/PRINCIPAL FINDINGS: Associations between CYP2R1, GC, and DHCR7 genotypes that are determinants of reduced 25-hydroxyvitamin D (25[OH]D3) serum levels and the risk of HCV-related HCC development were investigated for 1279 chronic hepatitis C patients with HCC and 4325 without HCC, respectively. 25-hydroxyvitamin D 118-137 7-dehydrocholesterol reductase Homo sapiens 69-74 24642724-0 2013 Effect of polymorphisms in the NADSYN1/DHCR7 locus (rs12785878 and rs1790349) on plasma 25-hydroxyvitamin D levels and coronary artery disease incidence. 25-hydroxyvitamin D 88-107 7-dehydrocholesterol reductase Homo sapiens 39-44 24642724-1 2013 BACKGROUND/AIMS: Recent genome-wide association studies have identified the rs1790349 and rs12785878 single-nucleotide polymorphisms (SNPs), present in the NADSYN1/DHCR7 locus, as an influential player on circulating 25-hydroxyvitamin D [25(OH)D] levels, which itself has been linked to various diseases including cardiovascular disease (CVD). 25-hydroxyvitamin D 217-236 7-dehydrocholesterol reductase Homo sapiens 164-169 25406188-8 2014 Each increase in DHCR7/CYP2R1 allele score was associated with a 1.9 nmol/L lower plasma 25-hydroxyvitamin D concentration and with increased all cause, cancer, and other mortality but not with cardiovascular mortality. 25-hydroxyvitamin D 89-108 7-dehydrocholesterol reductase Homo sapiens 17-22 22576297-1 2012 UNLABELLED: Recently, genome-wide studies identified genetic variants that affect serum 25-hydroxyvitamin D levels in healthy populations (rs12785878, near dehydrocholesterol reductase, DHCR7; rs10741657, at CYP2R1; and rs7041, at vitamin D binding protein, GC). 25-hydroxyvitamin D 88-107 7-dehydrocholesterol reductase Homo sapiens 186-191 21972121-1 2012 Recent studies have identified common variants in or near GC, CYP2R1 and NADSYN1/DHCR7 to be associated with 25-hydroxyvitamin D [25(OH)D] levels in European populations. 25-hydroxyvitamin D 109-128 7-dehydrocholesterol reductase Homo sapiens 81-86 29343764-2 2018 Previous GWAS of serum 25-hydroxyvitamin D concentrations have identified four genome-wide significant loci (GC, NADSYN1/DHCR7, CYP2R1, CYP24A1). 25-hydroxyvitamin D 23-42 7-dehydrocholesterol reductase Homo sapiens 121-126 24663808-0 2014 A serum 25-hydroxyvitamin D concentration-associated genetic variant in DHCR7 interacts with type 2 diabetes status to influence subclinical atherosclerosis (measured by carotid intima-media thickness). 25-hydroxyvitamin D 8-27 7-dehydrocholesterol reductase Homo sapiens 72-77