PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21110005-6 2011 Our aim was to characterize the vitamin-D status of religious Jewish males according to sun exposure and outdoor activity, and study the correlation between serum 25-hydroxyvitamin D (25(OH) D) and PTH level. 25-hydroxyvitamin D 163-182 parathyroid hormone Homo sapiens 198-201 21521334-0 2011 The relationship between PTH and 25-hydroxy vitamin D early in pregnancy. 25-hydroxyvitamin D 33-53 parathyroid hormone Homo sapiens 25-28 21272724-13 2011 CONCLUSIONS: The significant association between 25-hydroxyvitamin D levels (and 25-hydroxyvitamin D/PTH ratio) and the ability to function in women with hip fractures was not mediated by aLM assessed by DXA. 25-hydroxyvitamin D 49-68 parathyroid hormone Homo sapiens 101-104 21713425-1 2011 BACKGROUND: The connection of 25-hydroxyvitamin D [25(OH)D] with bone metabolism is reported to occur indirectly through parathyroid hormone (PTH) activity. 25-hydroxyvitamin D 30-49 parathyroid hormone Homo sapiens 121-140 21567168-7 2011 The PTH changes were significantly correlated with serum 25-hydroxyvitamin D (25OHD) levels. 25-hydroxyvitamin D 57-76 parathyroid hormone Homo sapiens 4-7 21998600-2 2011 Levels of 25-hydroxyvitamin D (25(OH)D) show an inverse correlation with those of intact PTH and phosphorus. 25-hydroxyvitamin D 10-29 parathyroid hormone Homo sapiens 89-92 21179052-12 2011 The 25-hydroxyvitamin D values above 30 ng/ml can safely discard "hyper PTH". 25-hydroxyvitamin D 4-23 parathyroid hormone Homo sapiens 72-75 21366811-6 2011 S-25-hydroxyvitamin D was inversely associated with PTH (p = 0.02) and positively associated with S-1,25-dihydroxyvitamin D (p = 0.02). 25-hydroxyvitamin D 0-21 parathyroid hormone Homo sapiens 52-55 20861214-0 2010 An inflection point of serum 25-hydroxyvitamin D for maximal suppression of parathyroid hormone is not evident from multi-site pooled data in children and adolescents. 25-hydroxyvitamin D 29-48 parathyroid hormone Homo sapiens 76-95 20544293-1 2010 BACKGROUND: Deficiency of 25-hydroxyvitamin D (25OHD) is a stimulus for the secretion of parathyroid hormone (PTH). 25-hydroxyvitamin D 26-45 parathyroid hormone Homo sapiens 89-108 20642877-2 2010 The present study aimed to examine the associations between serum concentrations of 25-hydroxyvitamin D (25(OH)D) and parathyroid hormone (PTH) and the presence of depression among US adults. 25-hydroxyvitamin D 84-103 parathyroid hormone Homo sapiens 118-137 21034990-4 2010 Under the influence of parathyroid hormone, the kidney then converts 25-hydroxyvitamin D to 1,25-dihydroxyvitamin D, the biologically active, hormonal form of the nutrient that is important in the metabolism of calcium and phosphorus and is critical in building and maintaining healthy bones. 25-hydroxyvitamin D 69-88 parathyroid hormone Homo sapiens 23-42 20861214-1 2010 In adults, maximal suppression of serum parathyroid hormone (PTH) has commonly been used to determine the sufficiency of serum 25-hydroxyvitamin D [25(OH)D]. 25-hydroxyvitamin D 127-146 parathyroid hormone Homo sapiens 40-59 19213756-3 2009 RESULTS: Only when the 25-hydroxyvitamin D (25(OH)D) level dropped below 25 nmol/l, was there a significant rise in PTH. 25-hydroxyvitamin D 23-42 parathyroid hormone Homo sapiens 116-119 20155247-0 2010 Effects of 25-hydroxyvitamin D level and its change on parathyroid hormone in premenopausal Chinese women. 25-hydroxyvitamin D 11-30 parathyroid hormone Homo sapiens 55-74 20155247-3 2010 INTRODUCTION: The upper level of 25-hydroxyvitamin D [25(OH)D] which constitutes a long-term bone health risk by causing elevated PTH levels is uncertain. 25-hydroxyvitamin D 33-52 parathyroid hormone Homo sapiens 130-133 20601288-1 2010 INTRODUCTION: Previous papers investigating vitamin D status have often outlined the significant relationships between serum parathyroid hormone (PTH) and 25-hydroxyvitamin D (25OHD), but the influence of ionized calcium levels has not been concomitantly considered. 25-hydroxyvitamin D 155-174 parathyroid hormone Homo sapiens 125-144 20089790-0 2010 Three-phase model harmonizes estimates of the maximal suppression of parathyroid hormone by 25-hydroxyvitamin D in persons 65 years of age and older. 25-hydroxyvitamin D 92-111 parathyroid hormone Homo sapiens 69-88 20089790-1 2010 The concentration or threshold of 25-hydroxyvitamin D [25(OH)D] needed to maximally suppress intact serum parathyroid hormone (iPTH) has been suggested as a measure of optimal vitamin D status. 25-hydroxyvitamin D 34-53 parathyroid hormone Homo sapiens 106-125 19158198-1 2009 CONTEXT: Serum 25-hydroxyvitamin D [25(OH)D] may influence serum PTH and other parameters of bone health up to a threshold concentration, which may be between 25 and 80 nmol/liter. 25-hydroxyvitamin D 15-34 parathyroid hormone Homo sapiens 65-68 19261615-1 2009 Although parathyroid hormone (PTH) induces 25-hydroxyvitamin D(3) (25(OH)D(3)) 1alpha-hydroxylase (1alpha(OH)ase) under hypocalcemic conditions, previous studies showed that calcitonin, not PTH, has an important role in the maintenance of serum 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) under normocalcemic conditions. 25-hydroxyvitamin D 43-62 parathyroid hormone Homo sapiens 30-33 19436945-1 2009 Insufficient levels of serum 25-hydroxyvitamin D [25(OH)D] lead to low bone mineral density (BMD) by increasing serum levels of intact parathyroid hormone (PTH), and are associated with a high mortality rate. 25-hydroxyvitamin D 29-48 parathyroid hormone Homo sapiens 135-154 19436945-1 2009 Insufficient levels of serum 25-hydroxyvitamin D [25(OH)D] lead to low bone mineral density (BMD) by increasing serum levels of intact parathyroid hormone (PTH), and are associated with a high mortality rate. 25-hydroxyvitamin D 29-48 parathyroid hormone Homo sapiens 156-159 18519464-7 2008 There was a significant inverse correlation between 25-hydroxyvitamin D and parathyroid hormone levels. 25-hydroxyvitamin D 52-71 parathyroid hormone Homo sapiens 76-95 19235038-2 2009 The association between elevated parathyroid hormone (PTH) and low 25-hydroxyvitamin D (25-OH-VitD) in plasma is used to define vitamin D deficiency, yet their associated mechanistic pathways are unclear. 25-hydroxyvitamin D 67-86 parathyroid hormone Homo sapiens 33-52 19098950-2 2008 The threshold of 25-hydroxyvitamin D above which PTH plateaus, is a criterion often used to define vitamin D adequacy. 25-hydroxyvitamin D 17-36 parathyroid hormone Homo sapiens 49-52 19098950-7 2008 The lower plasma 25-hydroxyvitamin D in early spring versus summer was associated with a 0.2 pmol/L (p<0.001) higher PTH concentration. 25-hydroxyvitamin D 17-36 parathyroid hormone Homo sapiens 120-123 19098950-9 2008 DISCUSSION: The higher PTH concentration in winter than summer suggests that the low 25-hydroxyvitamin D concentration in the winter months may be having an adverse effect on bone health. 25-hydroxyvitamin D 85-104 parathyroid hormone Homo sapiens 23-26 18524740-10 2008 Older age, winter season, higher body mass index, black race/ethnicity, and elevated parathyroid hormone concentrations were associated with lower 25-hydroxyvitamin D concentrations. 25-hydroxyvitamin D 147-166 parathyroid hormone Homo sapiens 85-104 18544628-8 2008 PTH concentration was suppressed by increasing 25-hydroxyvitamin D (P < 0.0001), but not 1,25-dihydroxyvitamin D (P > 0.05) concentration. 25-hydroxyvitamin D 47-66 parathyroid hormone Homo sapiens 0-3 18519464-10 2008 The inverse relationship between 25-hydroxyvitamin D and parathyroid hormone levels suggests a physiologic impact of insufficient vitamin D levels that may contribute to low bone mass or worsen the primary bone disease. 25-hydroxyvitamin D 33-52 parathyroid hormone Homo sapiens 57-76 18290721-5 2007 PTH suppression with increasing serum 25-hydroxyvitamin D varies with race in adolescents. 25-hydroxyvitamin D 38-57 parathyroid hormone Homo sapiens 0-3 18239958-6 2008 Serum log whole PTH/intact PTH ratio, which increased as serum Ca and GFR decreased, retained a negative correlation in those with serum 25-hydroxyvitamin D levels below 20 ng/ml, but not in those above 20 ng/ml. 25-hydroxyvitamin D 137-156 parathyroid hormone Homo sapiens 16-19 18239958-6 2008 Serum log whole PTH/intact PTH ratio, which increased as serum Ca and GFR decreased, retained a negative correlation in those with serum 25-hydroxyvitamin D levels below 20 ng/ml, but not in those above 20 ng/ml. 25-hydroxyvitamin D 137-156 parathyroid hormone Homo sapiens 27-30 17431533-0 2007 Glomerular filtration rate is a major determinant of the relationship between 25-hydroxyvitamin D and parathyroid hormone. 25-hydroxyvitamin D 78-97 parathyroid hormone Homo sapiens 102-121 17595934-1 2007 OBJECTIVE: To examine the relationship between bone mass and serum levels of 25-hydroxyvitamin D and parathyroid hormone in African-American adolescent girls. 25-hydroxyvitamin D 77-96 parathyroid hormone Homo sapiens 101-120 18063090-3 2007 This study examined the impact of 25-hydroxyvitamin D (25OHD) deficiency on perioperative PTH kinetics and outcomes following parathyroidectomy. 25-hydroxyvitamin D 34-53 parathyroid hormone Homo sapiens 90-93 16960175-1 2006 BACKGROUND: Optimal vitamin D status for the prevention of osteoporosis has been inferred from examinations of the serum 25-hydroxyvitamin D [25(OH)D] concentration below which there is an increase in serum parathyroid hormone (PTH). 25-hydroxyvitamin D 121-140 parathyroid hormone Homo sapiens 207-226 16901796-6 2006 These abnormalities were likely due to vitamin D deficiency, evidenced by a 25-hydroxyvitamin D level of 14 ng/mL, which provoked an elevation of the serum parathyroid hormone (PTH) concentration, documented by an intact PTH of 213 pg/mL (normal, 15 to 65) and a whole PTH (1-84 PTH) of 70.6 pg/mL (normal, 7 to 36). 25-hydroxyvitamin D 76-95 parathyroid hormone Homo sapiens 156-175 16644777-0 2006 Renal function and 25-hydroxyvitamin D concentrations predict parathyroid hormone levels in renal transplant patients. 25-hydroxyvitamin D 19-38 parathyroid hormone Homo sapiens 62-81 15531500-0 2004 Serum parathyroid hormone is associated with increased mortality independent of 25-hydroxy vitamin d status, bone mass, and renal function in the frail and very old: a cohort study. 25-hydroxyvitamin D 80-100 parathyroid hormone Homo sapiens 6-25 16937272-0 2006 Threshold value of serum 25-hydroxyvitamin D concentration in relation to elevated serum parathyroid hormone concentrations in elderly Japanese women. 25-hydroxyvitamin D 25-44 parathyroid hormone Homo sapiens 89-108 16937272-1 2006 This study was designed to determine the threshold value for 25-hydroxyvitamin D [25(OH)D] concentration in relation to elevated serum parathyroid hormone (PTH) concentrations in elderly Japanese women. 25-hydroxyvitamin D 61-80 parathyroid hormone Homo sapiens 135-154 15175848-0 2005 Low levels of 25-hydroxy vitamin D are associated with elevated parathyroid hormone in healthy adolescent females. 25-hydroxyvitamin D 14-34 parathyroid hormone Homo sapiens 64-83 15175848-1 2005 This study aimed to investigate the relationship between 25-hydroxyvitamin D [25(OH)D)] and parathyroid hormone (PTH) levels in adolescent females residing in a northern climate. 25-hydroxyvitamin D 57-76 parathyroid hormone Homo sapiens 92-111 15175848-1 2005 This study aimed to investigate the relationship between 25-hydroxyvitamin D [25(OH)D)] and parathyroid hormone (PTH) levels in adolescent females residing in a northern climate. 25-hydroxyvitamin D 57-76 parathyroid hormone Homo sapiens 113-116 11470722-3 2001 The effect of serum 25-hydroxyvitamin D [25(OH)D] concentrations on parathyroid hormone concentrations and bone mineral density (BMD) has not been well studied cross-sectionally in adolescents. 25-hydroxyvitamin D 20-39 parathyroid hormone Homo sapiens 68-87 12936933-0 2003 Association of low 25-hydroxyvitamin D concentrations with elevated parathyroid hormone concentrations and low cortical bone density in early pubertal and prepubertal Finnish girls. 25-hydroxyvitamin D 19-38 parathyroid hormone Homo sapiens 68-87 12753264-7 2003 The prevalence of secondary hyperparathyroidism (PTH>65 pg/mL) according to 25-hydroxyvitamin D levels was 33% (<10 ng/mL), 16% (10-18 ng/mL), and 12% (>18 ng/mL), respectively. 25-hydroxyvitamin D 79-98 parathyroid hormone Homo sapiens 49-52 12753264-9 2003 The independent predictors for PTH were 25-hydroxyvitamin D and serum creatinine in both sexes, but age was a predictor only in men. 25-hydroxyvitamin D 40-59 parathyroid hormone Homo sapiens 31-34 10794753-15 2000 In patients with progressive renal failure, I-PTH was related to Ca(2+) (r = -0.66; P <0.0001), CrCl (r = -0.61; P <0.001), 1,25-dihydroxyvitamin D (r = -0.40; P <0.05), and 25-hydroxyvitamin D (r = -0.49; P <0.01) by simple linear regression. 25-hydroxyvitamin D 183-202 parathyroid hormone Homo sapiens 46-49 11305079-1 2001 The aim of this study was to determine possible associations between bone mineral density (BMD), 25-hydroxyvitamin D (25(OH)D) and intact parathyroid hormone (PTH). 25-hydroxyvitamin D 97-116 parathyroid hormone Homo sapiens 138-157 11305079-1 2001 The aim of this study was to determine possible associations between bone mineral density (BMD), 25-hydroxyvitamin D (25(OH)D) and intact parathyroid hormone (PTH). 25-hydroxyvitamin D 97-116 parathyroid hormone Homo sapiens 159-162 11214353-0 2000 Serum parathyroid hormone in healthy Japanese women in relation to serum 25-hydroxyvitamin D. 25-hydroxyvitamin D 73-92 parathyroid hormone Homo sapiens 6-25 11214353-1 2000 The aim of this work was to clarify levels of serum parathyroid hormone (PTH) in healthy adult women and to study the relationship between PTH and 25-hydroxyvitamin D [25(OH)D]. 25-hydroxyvitamin D 147-166 parathyroid hormone Homo sapiens 139-142 8852944-12 1996 In elderly women, 20 years since menopause and over, but not in younger ones, serum PTH was negatively correlated with serum 25-hydroxyvitamin D (r = -0.22, p < 0.05) and explained only 5-8% of the bone turnover variance (p < 0.01-0.001). 25-hydroxyvitamin D 125-144 parathyroid hormone Homo sapiens 84-87 8865145-3 1996 The alkaline phosphatase and parathyroid hormone levels were clearly higher when the 25 hydroxyvitamin D level was below 10 nmol/1. 25-hydroxyvitamin D 85-104 parathyroid hormone Homo sapiens 29-48 9886454-8 1999 Parathyroid hormone was abnormally increased in 15 patients (17%) and correlated negatively with serum 25-hydroxyvitamin D, indicating compensatory hyperparathyroidism. 25-hydroxyvitamin D 103-122 parathyroid hormone Homo sapiens 0-19 9141544-6 1997 By multivariate analysis, serum 25-hydroxyvitamin D levels were highly predictive of serum PTH levels regardless of menopausal status, whereas serum estrone levels were predictive of markers of bone resorption in the postmenopausal women. 25-hydroxyvitamin D 32-51 parathyroid hormone Homo sapiens 91-94 1422960-2 1992 We found an inverse correlation between serum 25-hydroxyvitamin D (25OHD) and immunoreactive parathyroid hormone (PTH), and we postulated that over time, women with lower 25OHD would lose more bone because of increased bone remodeling induced by secondary hyperparathyroidism. 25-hydroxyvitamin D 46-65 parathyroid hormone Homo sapiens 93-112 9231942-3 1994 Parathyroid hormone concentrations were inversely related to 25-hydroxyvitamin D concentrations (p < 0.0001). 25-hydroxyvitamin D 61-80 parathyroid hormone Homo sapiens 0-19 8373837-0 1993 Serum 25-hydroxyvitamin D levels in normal subjects: seasonal variations and relationships with parathyroid hormone and osteocalcin. 25-hydroxyvitamin D 6-25 parathyroid hormone Homo sapiens 96-115 34602077-1 2021 BACKGROUND: To investigate the causal association between serum 25-hydroxyvitamin D (25OHD), calcium (Ca), and parathyroid hormone (PTH) levels and the risk of coronary artery disease (CAD) in patients with diabetes using a Mendelian randomization approach. 25-hydroxyvitamin D 64-83 parathyroid hormone Homo sapiens 111-130 34948669-1 2021 Background: The aim of this study was to assess the relationship between serum 25-hydroxyvitamin D (25(OH)D) and serum intact parathyroid hormone (PTH) in Chinese childbearing women, and to estimate the optimum threshold of 25(OH)D that maximally inhibits the PTH, which is considered to be the optimal status for vitamin D sufficiency. 25-hydroxyvitamin D 79-98 parathyroid hormone Homo sapiens 126-145 34948669-1 2021 Background: The aim of this study was to assess the relationship between serum 25-hydroxyvitamin D (25(OH)D) and serum intact parathyroid hormone (PTH) in Chinese childbearing women, and to estimate the optimum threshold of 25(OH)D that maximally inhibits the PTH, which is considered to be the optimal status for vitamin D sufficiency. 25-hydroxyvitamin D 79-98 parathyroid hormone Homo sapiens 147-150 34948669-1 2021 Background: The aim of this study was to assess the relationship between serum 25-hydroxyvitamin D (25(OH)D) and serum intact parathyroid hormone (PTH) in Chinese childbearing women, and to estimate the optimum threshold of 25(OH)D that maximally inhibits the PTH, which is considered to be the optimal status for vitamin D sufficiency. 25-hydroxyvitamin D 79-98 parathyroid hormone Homo sapiens 260-263 34602077-1 2021 BACKGROUND: To investigate the causal association between serum 25-hydroxyvitamin D (25OHD), calcium (Ca), and parathyroid hormone (PTH) levels and the risk of coronary artery disease (CAD) in patients with diabetes using a Mendelian randomization approach. 25-hydroxyvitamin D 64-83 parathyroid hormone Homo sapiens 132-135 34278997-11 2021 According to the parathyroid hormone, the favorable serum 25-Hydroxyvitamin D level was 20 to 49.9 ng/mL in our kidney stone formers. 25-hydroxyvitamin D 58-77 parathyroid hormone Homo sapiens 17-36 35598638-2 2022 PTH promotes calcium release from the bone, renal calcium reabsorption and phosphate excretion, and conversion of 25-hydroxyvitamin D to 1,25-dihydroxyvitamin D-3. 25-hydroxyvitamin D 114-133 parathyroid hormone Homo sapiens 0-3 35626939-9 2022 RESULTS: There is a significant difference in the 25-hydroxyvitamin D levels distribution between LEF and HEF (p < 0.001) and PTH levels (p = 0.002). 25-hydroxyvitamin D 50-69 parathyroid hormone Homo sapiens 126-129 35626939-12 2022 For the group of patients with HEF, there was only a significantly positive correlation between 25-hydroxyvitamin D and PTH levels (p < 0.001). 25-hydroxyvitamin D 96-115 parathyroid hormone Homo sapiens 120-123 2848397-2 1988 We showed previously that obese white subjects have low serum vitamin D and 25-hydroxyvitamin D (25-OHD) with increased serum-immunoreactive parathyroid hormone (PTH) and 1,25-(OH)2D, low urinary calcium, and increased urinary cyclic adenosine 3",5"-monophosphate (cyclic AMP) compared with nonobese white individuals. 25-hydroxyvitamin D 76-95 parathyroid hormone Homo sapiens 141-160 6255001-1 1980 The role of parathyroid hormone (PTH) and cAMP in the hydroxylation of 25-hydroxyvitamin D to 1,25-dihydroxyvitamin D [1,25-(OH)2D] was explored in two young male volunteers and a patient with pseudohypoparathyroidism type I. 25-hydroxyvitamin D 71-90 parathyroid hormone Homo sapiens 12-31 6611345-2 1984 These elevated PTH concentrations, though not as high as those in osteomalacic patients with hypocalcemia, often persisted despite treatment with vitamin D, normalization of 25-hydroxyvitamin D, and an increase in calcium concentrations. 25-hydroxyvitamin D 174-193 parathyroid hormone Homo sapiens 15-18 33109180-2 2020 In human research, the parathyroid hormone concentration in relation to the 25-hydroxyvitamin D concentration is used to determine vitamin D deficiency. 25-hydroxyvitamin D 76-95 parathyroid hormone Homo sapiens 23-42 33995282-2 2021 We aimed to describe the combined effects of 25-hydroxy vitamin D (25(OH)D), glomerular filtration rate (GFR) and age on serum PTH levels across the whole clinical spectrum. 25-hydroxyvitamin D 45-65 parathyroid hormone Homo sapiens 127-130 33932619-6 2021 Serum 1,25-dihydroxyvitamin D3 increased significantly (P<0.001) and 25-hydroxyvitamin D levels decreased during PTH 1-34 injections compared to calcitriol therapy (P<0.01). 25-hydroxyvitamin D 69-88 parathyroid hormone Homo sapiens 113-118 33716964-8 2021 Correlation analysis revealed that patients with higher serum levels of parathyroid hormone (PTH) and calcium presented higher serum levels of bone turnover markers (BTMs) and lower 25-hydroxy-vitamin D (25OHD) values (P<0.001). 25-hydroxyvitamin D 182-202 parathyroid hormone Homo sapiens 72-91 33022030-0 2021 Racial differences in the relationship between high-normal 25-hydroxy vitamin d and parathyroid hormone levels in early stage chronic kidney disease. 25-hydroxyvitamin D 59-79 parathyroid hormone Homo sapiens 84-103 32367244-4 2020 PURPOSE: Seasonal variation of parathyroid hormone (PTH) and its dependency on serum 25-hydroxy vitamin D (25(OH)D) levels are well-described. 25-hydroxyvitamin D 85-105 parathyroid hormone Homo sapiens 31-50 33114615-12 2020 25-hydroxyvitamin D concentration was inversely correlated with parathyroid hormone (rho = -0.146, p = 0.013). 25-hydroxyvitamin D 0-19 parathyroid hormone Homo sapiens 64-83 32638247-0 2020 Nutritional Status of Obese Taiwanese Before Bariatric-Metabolic Surgery and Their Serum 25-Hydroxyvitamin D Concentrations for Maximal Suppression of Parathyroid Hormone. 25-hydroxyvitamin D 89-108 parathyroid hormone Homo sapiens 151-170 32367244-4 2020 PURPOSE: Seasonal variation of parathyroid hormone (PTH) and its dependency on serum 25-hydroxy vitamin D (25(OH)D) levels are well-described. 25-hydroxyvitamin D 85-105 parathyroid hormone Homo sapiens 52-55 32231092-1 2020 Optimal vitamin D status has commonly been defined as the level of 25-hydroxyvitamin D (25(OH)D) at which parathyroid hormone (PTH) concentrations would be maximally suppressed, represented by an observed minimum plateau. 25-hydroxyvitamin D 67-86 parathyroid hormone Homo sapiens 106-125 31923385-1 2020 PURPOSE: We investigated prevalence, determinants, seasonal changes, and time trends in hypovitaminosis D. We derived a desirable serum 25-hydroxy-vitamin D (25OHD) level in adults/elderly by evaluating the 25OHD-parathyroid hormone (PTH) exponential relationship. 25-hydroxyvitamin D 136-156 parathyroid hormone Homo sapiens 207-232 31923385-1 2020 PURPOSE: We investigated prevalence, determinants, seasonal changes, and time trends in hypovitaminosis D. We derived a desirable serum 25-hydroxy-vitamin D (25OHD) level in adults/elderly by evaluating the 25OHD-parathyroid hormone (PTH) exponential relationship. 25-hydroxyvitamin D 136-156 parathyroid hormone Homo sapiens 234-237 32231092-1 2020 Optimal vitamin D status has commonly been defined as the level of 25-hydroxyvitamin D (25(OH)D) at which parathyroid hormone (PTH) concentrations would be maximally suppressed, represented by an observed minimum plateau. 25-hydroxyvitamin D 67-86 parathyroid hormone Homo sapiens 127-130 31729682-3 2019 Biological studies were remarkable for PTH-independent severe hypercalcemia with low 25-hydroxyvitamin D and a paradoxically elevated 1,25-dihydroxyvitamin D. 25-hydroxyvitamin D 85-104 parathyroid hormone Homo sapiens 39-42 29597231-7 2018 PTH stimulates the renal conversion of 25-hydroxyvitamin D (25[OH]D) to 1,25(OH)2D, likely over several hours, which in turn will augment intestinal calcium absorption. 25-hydroxyvitamin D 39-58 parathyroid hormone Homo sapiens 0-3 31129357-0 2019 The relative influence of serum ionized calcium and 25-hydroxyvitamin D in regulating PTH secretion in healthy subjects. 25-hydroxyvitamin D 52-71 parathyroid hormone Homo sapiens 86-89 29548779-5 2018 Parathyroid hormone was suppressed (15 pg/mL), associated with a low-normal 25-hydroxyvitamin D (26 ng/mL) concentration but high 1,25-dihydroxyvitamin D concentration (92 pg/mL). 25-hydroxyvitamin D 76-95 parathyroid hormone Homo sapiens 0-19 29017107-2 2018 OBJECTIVE: Investigate the relationship between circulating PTH and 25 hydroxyvitamin D (25-OHD) levels and clinical tests of gait stability and balance as physical fall risk factors. 25-hydroxyvitamin D 68-87 parathyroid hormone Homo sapiens 60-63 31770397-1 2019 The level of serum 25-hydroxyvitamin D (25(OH)D) at which intact parathyroid hormone (iPTH) is maximally suppressed (suppression point) and below which PTH begins to rise (inflection point) has been used to define optimum 25(OH)D concentration. 25-hydroxyvitamin D 19-38 parathyroid hormone Homo sapiens 87-90 29931358-0 2018 Associations Between Change in Total and Free 25-Hydroxyvitamin D With 24,25-Dihydroxyvitamin D and Parathyroid Hormone. 25-hydroxyvitamin D 46-65 parathyroid hormone Homo sapiens 100-119 29796622-2 2018 During pregnancy, both gestational age and serum 25-hydroxyvitamin D [25(OH)D] concentrations may influence the concentrations of 1,25-dihydroxyvitamin D [1,25(OH)2D], 24,25-dihydroxyvitamin D [24,25(OH)2D], and parathyroid hormone (PTH). 25-hydroxyvitamin D 49-68 parathyroid hormone Homo sapiens 212-231 29806069-4 2018 PURPOSE: The present study was attempted to determine the prevalence of secondary hyperparathyroidism and also to analyze the mean value (cutoff) of 25-hydroxyvitamin D from where the PTH begins to rise in Indian postmenopausal women. 25-hydroxyvitamin D 149-168 parathyroid hormone Homo sapiens 184-187 29806069-18 2018 CONCLUSIONS: Majority of postmenopausal women of India had 25-hydroxyvitamin D deficiency with raised PTH levels. 25-hydroxyvitamin D 59-78 parathyroid hormone Homo sapiens 102-105 29806069-19 2018 The cutoff point of 25-hydroxyvitamin D at which PTH began to rise was found at 25 ng/ml which seems similar to that of the Caucasians. 25-hydroxyvitamin D 20-39 parathyroid hormone Homo sapiens 49-52 28222407-6 2016 The association between PTH status and BMD persisted after adjustment for age, body mass index, phosphate, albumin-adjusted total calcium, 25-hydroxyvitamin D, estimated glomerular filtration rate, and magnesium (P=0.01). 25-hydroxyvitamin D 139-158 parathyroid hormone Homo sapiens 24-27 27339172-3 2016 INTRODUCTION: We aim to examine the prevalence of vitamin D deficiency, characterize the temporal relationship between 25-hydroxyvitamin D levels (25(OH)D) and intact PTH (iPTH) according to seasons, and investigate potential associations between 25(OH)D levels and extra-skeletal outcomes in a Brazilian population. 25-hydroxyvitamin D 119-138 parathyroid hormone Homo sapiens 167-170 27116295-8 2016 RESULTS: We found a negative correlation between bioavailable 25-hydroxyvitamin D and PTH (r = -0.373, P = 0.018), but not with BMD at lumbar spine (r = -0.065, P = 0.682) or hip (r = -0.029, P = 0.857). 25-hydroxyvitamin D 62-81 parathyroid hormone Homo sapiens 86-89 28289433-0 2017 The serum level of 25-hydroxyvitamin D for maximal suppression of parathyroid hormone in children: the relationship between 25-hydroxyvitamin D and parathyroid hormone. 25-hydroxyvitamin D 19-38 parathyroid hormone Homo sapiens 66-85 28289433-0 2017 The serum level of 25-hydroxyvitamin D for maximal suppression of parathyroid hormone in children: the relationship between 25-hydroxyvitamin D and parathyroid hormone. 25-hydroxyvitamin D 19-38 parathyroid hormone Homo sapiens 148-167 27018622-5 2016 A PTH nomogram was applied to calculate the maximum expected PTH for existing levels of 25-hydroxyvitamin D. 25-hydroxyvitamin D 88-107 parathyroid hormone Homo sapiens 2-5 28164599-11 2016 Moreover, the 25-hydroxyvitamin D concentrations were negatively correlated to PTH proving the plausibility of the results. 25-hydroxyvitamin D 14-33 parathyroid hormone Homo sapiens 79-82 27018622-5 2016 A PTH nomogram was applied to calculate the maximum expected PTH for existing levels of 25-hydroxyvitamin D. 25-hydroxyvitamin D 88-107 parathyroid hormone Homo sapiens 61-64 26865585-8 2016 Weaker tumor PTH mRNA level was significantly associated with higher concentration of circulating 25-hydroxyvitamin D (P = 0.005). 25-hydroxyvitamin D 98-117 parathyroid hormone Homo sapiens 13-16 26865585-12 2016 Circulating 25-hydroxyvitamin D levels may influence tumor PTH expression in vivo. 25-hydroxyvitamin D 12-31 parathyroid hormone Homo sapiens 59-62 26843386-0 2016 Serum concentrations of 25-hydroxyvitamin D and its association with bone mineral density and serum parathyroid hormone levels during winter in urban males from Guiyang, Southwest China. 25-hydroxyvitamin D 24-43 parathyroid hormone Homo sapiens 100-119 26895390-2 2016 However, it is unclear whether the 25-hydroxyvitamin D (25-OH-D) concentration required for suppression of PTH (ie, suggesting vitamin D sufficiency) differs between pregnancy and the nongravid state. 25-hydroxyvitamin D 35-54 parathyroid hormone Homo sapiens 107-110 26824485-0 2016 Uric Acid-Induced Inflammation Is Mediated by the Parathyroid Hormone:25-Hydroxyvitamin D Ratio in Obese Adolescents. 25-hydroxyvitamin D 70-89 parathyroid hormone Homo sapiens 50-69 26843386-1 2016 Serum vitamin D (25-hydroxyvitamin D (25OHD)) may influence serum parathyroid hormone (PTH) levels and bone mineral density (BMD). 25-hydroxyvitamin D 17-36 parathyroid hormone Homo sapiens 66-85 26843386-1 2016 Serum vitamin D (25-hydroxyvitamin D (25OHD)) may influence serum parathyroid hormone (PTH) levels and bone mineral density (BMD). 25-hydroxyvitamin D 17-36 parathyroid hormone Homo sapiens 87-90 26168767-3 2015 PURPOSE: The purpose of the present study was to estimate the status of 25-hydroxyvitamin D (25(OH)D) and its correlation with parathyroid hormone in healthy Mexicans. 25-hydroxyvitamin D 72-91 parathyroid hormone Homo sapiens 127-146 26745256-1 2016 CONTEXT: Patients with 25-hydroxyvitamin D deficiency (25OHD <20 ng/ml) and primary hyperparathyroidism (PHPT) have more severe disease reflected by higher serum PTH levels compared to those with vitamin D levels in the insufficient (20-29 ng/ml) or replete range (>= 30 ng/ml). 25-hydroxyvitamin D 23-42 parathyroid hormone Homo sapiens 165-168 26640388-5 2015 In the univariate analysis, 25-hydroxyvitamin D was negatively related to age, parathyroid hormone (PTH), proteinuria, and Charlson index, while a positive relationship has emerged with hemoglobin level. 25-hydroxyvitamin D 28-47 parathyroid hormone Homo sapiens 79-98 26640388-5 2015 In the univariate analysis, 25-hydroxyvitamin D was negatively related to age, parathyroid hormone (PTH), proteinuria, and Charlson index, while a positive relationship has emerged with hemoglobin level. 25-hydroxyvitamin D 28-47 parathyroid hormone Homo sapiens 100-103 26640388-6 2015 On multiple regression analysis, only age and PTH levels were independently associated with 25-hydroxyvitamin D levels. 25-hydroxyvitamin D 92-111 parathyroid hormone Homo sapiens 46-49 26359185-0 2016 Association of 25-hydroxyvitamin D with areal and volumetric measures of bone mineral density and parathyroid hormone: impact of vitamin D-binding protein and its assays. 25-hydroxyvitamin D 15-34 parathyroid hormone Homo sapiens 98-117 26339419-3 2015 In this study, we analyzed association between promoter region sequence variants of PTH gene and circulating 25-hydroxy-vitamin D (25(OH)D) level. 25-hydroxyvitamin D 109-129 parathyroid hormone Homo sapiens 84-87 25751107-3 2015 OBJECTIVE: The purpose of this article was to analyze the relationship between PTH and age, controlling for 25-hydroxyvitamin D, phosphate, renal function, and ionized calcium. 25-hydroxyvitamin D 108-127 parathyroid hormone Homo sapiens 79-82 25135619-1 2015 BACKGROUND: To examine the relationship of serum 25-hydroxyvitamin D (25OHD) concentrations with serum parathyroid hormone (PTH) levels, body mass index (BMI), and environmental factors in a population of Caucasian children living at latitude 43 N. METHODS: Cross-sectional study on 288 children aged 1 month to 13 years who presented to a pediatric emergency unit during a 21-month period. 25-hydroxyvitamin D 49-68 parathyroid hormone Homo sapiens 103-122 24699783-8 2014 Parathyroid hormone, a potentially modifiable biological factor downstream from 25-hydroxyvitamin D, was responsible for the majority of this attenuation. 25-hydroxyvitamin D 80-99 parathyroid hormone Homo sapiens 0-19 24840809-9 2014 Further adjustment for PTH and 25-hydroxyvitamin D levels revealed that PTH but not 25-hydroxyvitamin D was an independent determinant of all BP parameters. 25-hydroxyvitamin D 31-50 parathyroid hormone Homo sapiens 72-75 24572984-0 2014 Circulating intact parathyroid hormone is suppressed at 25-hydroxyvitamin D concentrations >25 nmol/L in children. 25-hydroxyvitamin D 56-75 parathyroid hormone Homo sapiens 19-38 24787093-1 2014 OBJECTIVES: The aim of the study was to assess seasonal prevalence of vitamin D deficiency according to sex and to determine the relations between serum levels of 25-hydroxyvitamin D [25(OH)D] and parathyroid hormone (PTH) and sociodemographic characteristics in otherwise healthy schoolchildren during spring and autumn. 25-hydroxyvitamin D 163-182 parathyroid hormone Homo sapiens 197-216 24608866-2 2014 The association between 25-hydroxyvitamin D and serum calcium, phosphate and parathyroid hormone was studied. 25-hydroxyvitamin D 24-43 parathyroid hormone Homo sapiens 77-96 24423366-1 2014 CONTEXT: Low 25-hydroxyvitamin D levels are common in patients with primary hyperparathyroidism (PHPT) and associated with higher PTH levels and hungry bone syndrome after parathyroidectomy (PTX). 25-hydroxyvitamin D 13-32 parathyroid hormone Homo sapiens 130-133 24194967-3 2013 Our results demonstrate the presence of insufficiency of 25-hydroxyvitamin D (25OH-D) in many patients with various clinical forms, correlated with the expected increase of the values of Parathyroid Hormone (PTH). 25-hydroxyvitamin D 57-76 parathyroid hormone Homo sapiens 187-206 24423329-6 2014 After appropriate adjustment for confounders, 25-hydroxyvitamin D showed a weak inverse association with fasting plasma glucose (FPG; mean difference 1.0% per 1 SD; the ratio of geometric means (RGM) 0.99, 95% confidence interval (CI) 0.98, 1.00), and PTH was weakly associated with FPG (RGM 1.01, 95% CI 1.00, 1.02), but neither was associated with fasting insulin, postchallenge glucose, or GDM. 25-hydroxyvitamin D 46-65 parathyroid hormone Homo sapiens 252-255 24012652-3 2013 The aim of the present study was therefore to calculate assay specific PTH reference levels in EDTA plasma for the Architect (Abbott) in relation to 25-hydroxyvitamin D (25OHD) levels. 25-hydroxyvitamin D 149-168 parathyroid hormone Homo sapiens 71-74 23885046-1 2013 BACKGROUND: Secondary hyperparathyroidism, which is defined by a high concentration of intact parathyroid hormone when circulating 25-hydroxyvitamin D [25(OH)D] is low, is a functional indicator of vitamin D insufficiency and a sign of impaired calcium metabolism. 25-hydroxyvitamin D 131-150 parathyroid hormone Homo sapiens 94-113 24715441-0 2014 Relationship between 25-hydroxyvitamin D concentrations, serum calcium, and parathyroid hormone in apparently healthy Syrian people. 25-hydroxyvitamin D 21-40 parathyroid hormone Homo sapiens 76-95 23036072-5 2013 RESULTS: When examining overall mean circulating levels during clinical follow-up, serum 25-hydroxyvitamin D correlated highly significantly with plasma parathyroid hormone (PTH) (r = -0.23, P = 0.0003) and serum phosphate (r = 0.16, P = 0.0119). 25-hydroxyvitamin D 89-108 parathyroid hormone Homo sapiens 153-172 23509103-0 2013 The effect of obesity on the relationship between serum parathyroid hormone and 25-hydroxyvitamin D in women. 25-hydroxyvitamin D 80-99 parathyroid hormone Homo sapiens 56-75 24194967-3 2013 Our results demonstrate the presence of insufficiency of 25-hydroxyvitamin D (25OH-D) in many patients with various clinical forms, correlated with the expected increase of the values of Parathyroid Hormone (PTH). 25-hydroxyvitamin D 57-76 parathyroid hormone Homo sapiens 208-211 23635517-5 2013 RESULTS: High PTH variability was independently associated with lower 25-hydroxyvitamin D concentration and factors of lipid and glucose metabolism, whereas high FGF23 variability was mainly associated with lower baseline serum phosphorous. 25-hydroxyvitamin D 70-89 parathyroid hormone Homo sapiens 14-17 26236422-1 2013 Currently, there is widespread interest in establishing 25-hydroxy vitamin D (25OHD) level preventing a secondary elevation in parathyroid hormone (PTH). 25-hydroxyvitamin D 56-76 parathyroid hormone Homo sapiens 127-146 24375245-1 2013 UNLABELLED: The aim of the study was to describe the vitamin D status and its seasonal variations in women living in Riga, Latvia, to examine an association between the concentrations of plasma 25-hydroxyvitamin D [25(OH)D] and parathyroid hormone (PTH), and to determine the threshold for plasma 25(OH)D above which there is no further suppression of PTH. 25-hydroxyvitamin D 194-213 parathyroid hormone Homo sapiens 228-247 22933544-1 2012 CONTEXT: Several studies define optimal serum 25-hydroxyvitamin D (25-OHD) levels based on serum PTH level reaching an asymptote. 25-hydroxyvitamin D 46-65 parathyroid hormone Homo sapiens 97-100 22426307-1 2012 Parathyroid hormone (PTH) increases the conversion of 25-hydroxyvitamin D [25(OH)D] to 1,25 dihydroxyvitamin D [1,25(OH)(2)D]. 25-hydroxyvitamin D 54-73 parathyroid hormone Homo sapiens 0-19 22426307-1 2012 Parathyroid hormone (PTH) increases the conversion of 25-hydroxyvitamin D [25(OH)D] to 1,25 dihydroxyvitamin D [1,25(OH)(2)D]. 25-hydroxyvitamin D 54-73 parathyroid hormone Homo sapiens 21-24 21995281-2 2012 We examined the associations between the levels of 25-hydroxyvitamin D (25-D) and 1,25-dihydroxyvitamin D (1,25-D) and both eGFR and PTH. 25-hydroxyvitamin D 51-70 parathyroid hormone Homo sapiens 133-136 22390397-3 2012 Therefore, in the present study, nine SNPs related to the vitamin D receptor (VDR) gene and serum levels of 25-hydroxyvitamin D (25(OH)D), calcium, phosphate and parathyroid hormone (PTH) were related to height in 9471 subjects. 25-hydroxyvitamin D 108-127 parathyroid hormone Homo sapiens 183-186 22551880-2 2012 Our goal was to ascertain whether 25-hydroxyvitamin D (25(OH)D) status related to PTH levels in this patient cohort. 25-hydroxyvitamin D 34-53 parathyroid hormone Homo sapiens 82-85 22624410-2 2012 The aim of this study was to establish the prevalence of inadequate serum 25-hydroxyvitamin D [25(OH)D] concentrations in postmenopausal Serbian women with seasonal variations of 25(OH)D, in relation to parathyroid hormone (PTH) and bone mineral density (BMD). 25-hydroxyvitamin D 74-93 parathyroid hormone Homo sapiens 203-222 21606669-4 2012 We examined the association between serum 25-hydroxyvitamin D (25OHD) level and serum PTH level in 14,681 participants aged >=6 yr. We also evaluated the 25OHD-PTH association using 2 thresholds of hyperparathyroidism: PTH>=45 pg/ml and >=75 pg/ml. 25-hydroxyvitamin D 42-61 parathyroid hormone Homo sapiens 86-89 23128574-3 2012 SUMMARY: PTH promotes bone resorption, decreases urinary calcium excretion, enhances the conversion of 25-hydroxyvitamin D to 1, 25-dihydroxyvitamin D and increases intestinal calcium absorption and phosphate renal excretion. 25-hydroxyvitamin D 103-122 parathyroid hormone Homo sapiens 9-12 23497722-1 2012 BACKGROUND: Both obesity and type 2 diabetes are associated with hypovitaminosis D. The aims of this study were to investigate the association of serum 25-hydroxy vitamin D (25(OH) D) and parathyroid hormone (PTH) concentration with body mass index (BMI) in type 2 diabetic patients compared to control subjects and their predicting role in obesity. 25-hydroxyvitamin D 152-172 parathyroid hormone Homo sapiens 188-207 23497722-1 2012 BACKGROUND: Both obesity and type 2 diabetes are associated with hypovitaminosis D. The aims of this study were to investigate the association of serum 25-hydroxy vitamin D (25(OH) D) and parathyroid hormone (PTH) concentration with body mass index (BMI) in type 2 diabetic patients compared to control subjects and their predicting role in obesity. 25-hydroxyvitamin D 152-172 parathyroid hormone Homo sapiens 209-212