PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30206265-4 2018 Targeted inhibition of Wnt/beta-catenin signaling by a small molecule, ICG-001, dose-dependently impeded the proliferation and transforming growth factor-beta1 (TGF-beta1)-mediated fibrogenic actions of LR-MSCs. Indocyanine Green 71-74 transforming growth factor beta 1 Homo sapiens 127-159 30206265-4 2018 Targeted inhibition of Wnt/beta-catenin signaling by a small molecule, ICG-001, dose-dependently impeded the proliferation and transforming growth factor-beta1 (TGF-beta1)-mediated fibrogenic actions of LR-MSCs. Indocyanine Green 71-74 transforming growth factor beta 1 Homo sapiens 161-170 27099262-7 2017 Inhibition of T-cell factor (TCF)/beta-catenin-mediated transcription with ICG-001 or genetic loss of beta-catenin also prevented TGF-beta-induced myofibroblasts formation. Indocyanine Green 75-78 transforming growth factor beta 1 Homo sapiens 130-138 26315281-10 2015 Either co-treatment or therapeutic administration of ICG-001 completely inhibited TGFbeta1-induced EMT. Indocyanine Green 53-56 transforming growth factor beta 1 Homo sapiens 82-90 26315281-11 2015 ICG-001 also reduced the expression of ck-5 and -19 independent of TGFbeta1. Indocyanine Green 0-3 transforming growth factor beta 1 Homo sapiens 67-75 22241478-3 2012 We previously demonstrated that ICG-001, a small molecule specific inhibitor of the beta-catenin/CBP (but not beta-catenin/p300) interaction, ameliorates and reverses pulmonary fibrosis and inhibits TGF-beta1-mediated alpha-smooth muscle actin (alpha-SMA) and collagen induction in AEC. Indocyanine Green 32-35 transforming growth factor beta 1 Homo sapiens 199-208