PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17981260-0 2008 Relationship of vitamin D with calbindin D9k and D28k expression in ameloblasts. Vitamin D 16-25 S100 calcium binding protein G Rattus norvegicus 31-44 17981260-1 2008 OBJECTIVE: Calbindin D9k (CB9k) and D28k (CB28k) are intracellular soluble calcium-binding proteins, whose expressions are considered to be regulated by vitamin D. Vitamin D 153-162 S100 calcium binding protein G Rattus norvegicus 11-24 9587402-2 1998 The calbindins are a family of vitamin D-dependent calcium-binding proteins found in the intestine (calbindin D-9k) and kidney (calbindin D-28k) and are thought to play a role in calcium transport and homeostasis. Vitamin D 31-40 S100 calcium binding protein G Rattus norvegicus 100-114 12032488-8 2002 Vitamin D compounds are believed to increase calcium absorption by inducing a calcium channel (epithelial calcium transporter or calcium transporter-1 [CaT1]) on the luminal membrane, a calcium-binding protein (Calbindin D9k) in the cytosol, and a calcium pump (plasma membrane calcium adenosine triphosphatase-1 [PMCA1]) on the basolateral membrane. Vitamin D 0-9 S100 calcium binding protein G Rattus norvegicus 211-224 10875229-0 2000 Transgenic analysis of the response of the rat calbindin-D 9k gene to vitamin D. Vitamin D 70-79 S100 calcium binding protein G Rattus norvegicus 47-61 7700214-7 1994 Vitamin D treatment raised the levels of calbindin-D9k in the normomagnesemic group (p < 0.01), but not significantly in the low Mg group. Vitamin D 0-9 S100 calcium binding protein G Rattus norvegicus 41-54 7602380-2 1995 Previous studies have shown that in enterocytes this Ca(2+)-pumping ATPase could be stimulated by vitamin D-dependent Ca(2+)-binding protein, calbindin-D9k, in ethylene glycol-bis(beta-aminoethyl ether)-N,N,N",N"-tetraacetic acid (EGTA)-free solutions. Vitamin D 98-107 S100 calcium binding protein G Rattus norvegicus 142-155 7651755-1 1995 The aim of this study was to investigate whether 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), the active metabolite of vitamin D, regulates the expression of rat placental calbindin-D9K mRNA. Vitamin D 63-72 S100 calcium binding protein G Rattus norvegicus 167-180 1466160-4 1992 The concentrations of two vitamin D-dependent calcium-binding proteins were also decreased: a low duodenal calbindin-D 9K concentration corresponding to the low intestinal active calcium absorption and a low serum osteocalcin concentration, corresponding to a low bone formation and highly correlated with serum IGF-I concentration. Vitamin D 26-35 S100 calcium binding protein G Rattus norvegicus 107-121 1312945-1 1992 Purified porcine erythrocyte membrane Ca(2+)-ATPase and 3":5"-cyclic nucleotide phosphodiesterase were stimulated in a dose-dependent, saturable manner with the vitamin D-dependent calcium binding protein from rat kidney, calbindin-D28k (CaBP-D28k). Vitamin D 161-170 S100 calcium binding protein G Rattus norvegicus 238-242 8396012-13 1993 Furthermore, comparison of the transient elevation of calcium absorption by OCT with its more prolonged effects on PTH and calbindin D9k indicates that each action of vitamin D compounds has a distinct biological half-life. Vitamin D 167-176 S100 calcium binding protein G Rattus norvegicus 123-136 1628219-1 1992 The localization of the vitamin D-dependent calcium-binding protein, calbindin D-28k (CaBP), was studied immunocytochemically in rat striated muscle. Vitamin D 24-33 S100 calcium binding protein G Rattus norvegicus 86-90 2305880-2 1990 Vitamin D metabolites, serum calcium and phosphorus levels, and the developmental appearance of vitamin D-dependent intestinal calcium binding protein (calbindin-D9k) was studied in normal and mutant rats of tl stock from 7 to 35 days of age. Vitamin D 96-105 S100 calcium binding protein G Rattus norvegicus 152-165 1777592-1 1991 There is strong evidence that vitamin D-dependent Ca(2+)-binding proteins, i.e., calbindin-D9k and calbindin-D28k, facilitate diffusion of Ca2+ through the cytosolic compartment of renal and intestinal cells, which transport Ca2+ transcellularly. Vitamin D 30-39 S100 calcium binding protein G Rattus norvegicus 81-94 2035635-4 1991 Lung, bladder, and especially prostate demonstrated 45Ca2+ bands comigrating with the intestinal vitamin D-related CaBP (CaBP-D9K; mol mass = 10.9 +/- 0.5 kDa). Vitamin D 97-106 S100 calcium binding protein G Rattus norvegicus 115-119 2035635-4 1991 Lung, bladder, and especially prostate demonstrated 45Ca2+ bands comigrating with the intestinal vitamin D-related CaBP (CaBP-D9K; mol mass = 10.9 +/- 0.5 kDa). Vitamin D 97-106 S100 calcium binding protein G Rattus norvegicus 121-129 2035635-9 1991 Immunoblot analysis of the 9-kDa CaBP in lung further confirmed its vitamin D independence. Vitamin D 68-77 S100 calcium binding protein G Rattus norvegicus 33-37 2035638-0 1991 Intestinal vitamin D-dependent calbindin-D9k and alkaline phosphatase in spontaneously hypertensive rats. Vitamin D 11-20 S100 calcium binding protein G Rattus norvegicus 31-44 1869447-1 1991 This electron microscope study describes the subcellular occurrence and distribution of immunoreactive calbindin-D9K in the trabecular metaphyseal and compact cortical bone of normal rats, rachitic vitamin-D-deficient rats, and rachitic rats given 1,25-(OH)2D3. Vitamin D 198-207 S100 calcium binding protein G Rattus norvegicus 103-116 2618862-0 1989 Structure of the rat vitamin D-induced calbindin-D9K gene and evolution of the EF-hand calcium-binding protein family. Vitamin D 21-30 S100 calcium binding protein G Rattus norvegicus 39-52 2471520-0 1989 Methylation of the vitamin D-dependent CaBP gene (calbindin 9 Kd) does not mediate tissue or vitamin D regulation. Vitamin D 19-28 S100 calcium binding protein G Rattus norvegicus 39-43 2551904-5 1989 Vitamin D-deficient rats responded to dexamethasone treatment (100 micrograms/100 g of body weight/day for 4 days) with a 2.5-fold increase in intestinal VDR mRNA which was accompanied by a 4-fold decrease in intestinal calbindin-D9k mRNA. Vitamin D 0-9 S100 calcium binding protein G Rattus norvegicus 220-233 2544409-3 1989 The present studies were undertaken to investigate the ability of EGF to accelerate the postnatal induction of the vitamin D-dependent intestinal calcium-binding protein, calbindin-D9k. Vitamin D 115-124 S100 calcium binding protein G Rattus norvegicus 171-184 2445747-1 1987 Regulation of the expression of vitamin D-dependent calcium-binding protein (Mr 9000 CaBP) gene by 1,25-dihydroxycholecalciferol (1,25-(OH)2D3) was studied in the rat duodenum. Vitamin D 32-41 S100 calcium binding protein G Rattus norvegicus 85-89 2511166-6 1989 Calbindin-D9K immunoreactivity was low or absent from the cytoplasm of osteocytes in trabecular bone from severely vitamin D-deficient rats and restored in vitamin D-deficient rats given a single dose of 1,25(OH)2-VitD3. Vitamin D 115-124 S100 calcium binding protein G Rattus norvegicus 0-13 2511166-6 1989 Calbindin-D9K immunoreactivity was low or absent from the cytoplasm of osteocytes in trabecular bone from severely vitamin D-deficient rats and restored in vitamin D-deficient rats given a single dose of 1,25(OH)2-VitD3. Vitamin D 156-165 S100 calcium binding protein G Rattus norvegicus 0-13 2511166-7 1989 Thus, the synthesis of immunoreactive calbindin-D9K by osteoblasts and osteocytes in trabecular bone is vitamin D-dependent. Vitamin D 104-113 S100 calcium binding protein G Rattus norvegicus 38-51 2445747-3 1987 A single 1,25-(OH)2D3 injection (650 pmol/100 g of body weight) induced a 2-fold increase in Mr 9000 CaBP gene transcription within 15 min in the duodenum of vitamin D-deficient rats. Vitamin D 158-167 S100 calcium binding protein G Rattus norvegicus 101-105 3885666-18 1985 The synthesis of D-CaBP is dependent upon vitamin D. Vitamin D 42-51 S100 calcium binding protein G Rattus norvegicus 19-23 3829120-1 1987 The molecular cloning of a cDNA fragment synthesised from rat duodenal mRNA coding for cholecalcin (calbindin), a 9000 Mr vitamin D-induced calcium-binding protein (CaBP), has been previously described. Vitamin D 122-131 S100 calcium binding protein G Rattus norvegicus 87-98 3550213-1 1987 The kidney distribution of 28 kDa vitamin D-induced calcium binding protein (CaBP) was studied in 15 fetuses (11 to 33 weeks old), six children and adults (12 days to 32 years old) by immunocytochemistry using a specific antibody to rat renal 28 kDa CaBP. Vitamin D 34-43 S100 calcium binding protein G Rattus norvegicus 250-254 3780535-1 1986 The in vivo stimulation of vitamin D-dependent calcium-binding protein (9 K CaBP) synthesis by 1,25-dihydroxycholecalciferol [1,25(OH)2D3] in the rat duodenum has been analyzed using a specific [32P]complementary DNA probe for rat 9 K CaBP and inhibitors of RNA transcription (actinomycin D, alpha-amanitin) or protein synthesis (cycloheximide). Vitamin D 27-36 S100 calcium binding protein G Rattus norvegicus 76-80 3780535-1 1986 The in vivo stimulation of vitamin D-dependent calcium-binding protein (9 K CaBP) synthesis by 1,25-dihydroxycholecalciferol [1,25(OH)2D3] in the rat duodenum has been analyzed using a specific [32P]complementary DNA probe for rat 9 K CaBP and inhibitors of RNA transcription (actinomycin D, alpha-amanitin) or protein synthesis (cycloheximide). Vitamin D 27-36 S100 calcium binding protein G Rattus norvegicus 235-239 3779381-1 1986 Rat brain vitamin D-dependent calcium-binding protein (D-CaBP) was assessed for vitamin D dependency, calcium binding and ultrastructural localization within neurons. Vitamin D 10-19 S100 calcium binding protein G Rattus norvegicus 57-61 3091093-1 1986 Cholecalciferol (calcitriol) the active hormonal form of vitamin D induces the synthesis of at least two intracellular calcium-binding proteins (Ka = 10(6) M-1), the cholecalcins (CaBP) in mammals. Vitamin D 57-66 S100 calcium binding protein G Rattus norvegicus 180-184 3459646-1 1986 The vitamin D-dependent calcium-binding protein (CaBP), cholecalcin or calbindin, is one of the best documented molecular expressions of 1,25-dihydroxyvitamin D, the hormonal metabolite of vitamin D. Vitamin D 4-13 S100 calcium binding protein G Rattus norvegicus 56-67 4027624-2 1985 This is the same protein as the vitamin D-dependent kidney CaBP, but its Purkinje cell level is apparently vitamin D independent. Vitamin D 32-41 S100 calcium binding protein G Rattus norvegicus 59-63 2862038-8 1985 The rapid production of fully functional cholecalcin mRNA, which was detectable as early as 1 h after a single dose of calcitriol to vitamin-D-deficient rats, provides convincing evidence that calcitriol increases 9-kDa cholecalcin production by increasing cholecalcin gene expression at the transcriptional level. Vitamin D 133-142 S100 calcium binding protein G Rattus norvegicus 41-52 3476614-10 1987 In developing rat molars, the time-course of appearance of CaBP, a protein dependent for its synthesis on the vitamin D endocrine system in other organ systems, suggests a potential direct role of this hormonal system in enamel mineralization. Vitamin D 110-119 S100 calcium binding protein G Rattus norvegicus 59-63 3688432-1 1987 A sensitive dot immunobinding assay has been developed for the quantitative determination of vitamin D-dependent calcium-binding protein (calbindin-D28k; CaBP) in rat and human kidney and brain. Vitamin D 93-102 S100 calcium binding protein G Rattus norvegicus 154-158 2943279-1 1986 The vitamin D-dependent, calcium-binding protein from rat kidney, calbindin D28k (renal CaBP) specifically stimulates Ca,Mg-ATPase activity of human erythrocyte plasma membranes in a dose-dependent, calcium-sensitive manner. Vitamin D 4-13 S100 calcium binding protein G Rattus norvegicus 88-92 3753716-0 1986 In situ detection of vitamin D-induced calcium-binding protein (9-kDa CaBP) messenger RNA in rat duodenum. Vitamin D 21-30 S100 calcium binding protein G Rattus norvegicus 64-74 3753716-1 1986 We have previously described the molecular cloning of a cDNA fragment synthesized from rat duodenal mRNA coding for a 9000-dalton vitamin D-induced calcium-binding protein (9-kDa CaBP) (3). Vitamin D 130-139 S100 calcium binding protein G Rattus norvegicus 148-184 6196546-1 1983 To extend our previous observations on the regulation of CaBP biosynthesis by 1,25-dihydroxyvitamin D3, we have studied the specific mRNA encoding this protein in vitamin D-deficient and in vitamin D-repleted rats as well as the rate of its induction after a single injection of 1,25(OH)2D3 to vitamin D-deficient animals. Vitamin D 92-101 S100 calcium binding protein G Rattus norvegicus 57-61 6196546-3 1983 CaBP-mRNA activity and cytoplasmic CaBP (measured by radioimmunoassay), dramatically decreased in rats previously fed a vitamin D-free diet for 5 weeks but neither parameter was zero. Vitamin D 120-129 S100 calcium binding protein G Rattus norvegicus 0-4 6196546-3 1983 CaBP-mRNA activity and cytoplasmic CaBP (measured by radioimmunoassay), dramatically decreased in rats previously fed a vitamin D-free diet for 5 weeks but neither parameter was zero. Vitamin D 120-129 S100 calcium binding protein G Rattus norvegicus 35-39 6196546-4 1983 In vitamin D-deficient rats, a single injection of 1,25(OH)2D3 led to an increase in CaBP-mRNA activity within 2 h. This CaBP-mRNA activity peaked at about 4-6 h and thereafter declined to low value by 48 h, and the changes in mRNA activity always preceded the changes in cytosolic CaBP concentration. Vitamin D 3-12 S100 calcium binding protein G Rattus norvegicus 85-89 6196546-4 1983 In vitamin D-deficient rats, a single injection of 1,25(OH)2D3 led to an increase in CaBP-mRNA activity within 2 h. This CaBP-mRNA activity peaked at about 4-6 h and thereafter declined to low value by 48 h, and the changes in mRNA activity always preceded the changes in cytosolic CaBP concentration. Vitamin D 3-12 S100 calcium binding protein G Rattus norvegicus 121-125 6196546-4 1983 In vitamin D-deficient rats, a single injection of 1,25(OH)2D3 led to an increase in CaBP-mRNA activity within 2 h. This CaBP-mRNA activity peaked at about 4-6 h and thereafter declined to low value by 48 h, and the changes in mRNA activity always preceded the changes in cytosolic CaBP concentration. Vitamin D 3-12 S100 calcium binding protein G Rattus norvegicus 121-125 443430-7 1979 The observed changes in calcium active transport with age and diet may be explained by the parallel changes in the vitamin D-dependent CaBP content of the intestine. Vitamin D 115-124 S100 calcium binding protein G Rattus norvegicus 135-139 734693-1 1978 Since intestinal calcium-binding protein (CaBP) can be regarded as an expression of the hormone-like action of 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3) on the duodenal enterocyte we have investigated the potential biological activity of 25R and 25S,26-(OH)2D3 (two recently synthesized epimers of vitamin D3 metabolite) to promote intestinal CaBP production as compared to bone calcium mobilization in vitamin D and calcium-deficient rats. Vitamin D 125-134 S100 calcium binding protein G Rattus norvegicus 42-46 828536-2 1976 Vitamin D-dependent CaBP isolated from Rat renal cortex (rCaBP) was measured in phosphorus-depleted (OP) and control (C) Rats, either vitamin D-deficient (OD) or vitamin D-supplemented (1 or 10 i. Vitamin D 0-9 S100 calcium binding protein G Rattus norvegicus 20-24 828536-2 1976 Vitamin D-dependent CaBP isolated from Rat renal cortex (rCaBP) was measured in phosphorus-depleted (OP) and control (C) Rats, either vitamin D-deficient (OD) or vitamin D-supplemented (1 or 10 i. Vitamin D 0-9 S100 calcium binding protein G Rattus norvegicus 57-62 828536-5 1976 The results indicated that phosphorus deprivation resulted in the increase in the vitamin D-dependent rCaBP as well as in the intestinal CaBP. Vitamin D 82-91 S100 calcium binding protein G Rattus norvegicus 102-107 828536-5 1976 The results indicated that phosphorus deprivation resulted in the increase in the vitamin D-dependent rCaBP as well as in the intestinal CaBP. Vitamin D 82-91 S100 calcium binding protein G Rattus norvegicus 103-107 828536-6 1976 As a marked hypercalciuria was noted in all OP Rats and as the rCaBP activity was high in vitamin D-supplemented Rats and hardly detectable in vitamin D-deficient Rats, the implication of the rCaBP in the large hypercalciuria can be definitely ruled out. Vitamin D 90-99 S100 calcium binding protein G Rattus norvegicus 63-68 828536-6 1976 As a marked hypercalciuria was noted in all OP Rats and as the rCaBP activity was high in vitamin D-supplemented Rats and hardly detectable in vitamin D-deficient Rats, the implication of the rCaBP in the large hypercalciuria can be definitely ruled out. Vitamin D 90-99 S100 calcium binding protein G Rattus norvegicus 192-197 828536-10 1976 The high CaBP activity probably resulting from the renal synthesis of 1,25-dihydroxycholecalciferol stimulated by phosphorus-deprivation could represent the molecular basis of the calcium tubular reabsorption increased by vitamin D. Vitamin D 222-231 S100 calcium binding protein G Rattus norvegicus 9-13 32604067-9 2020 Additionally, the upregulation of VDR, calbindin-D28k, and calbindin-D9k suggested that the vitamin D signaling system was amplified by vitamin D and 17beta-estradiol. Vitamin D 92-101 S100 calcium binding protein G Rattus norvegicus 59-72 32604067-9 2020 Additionally, the upregulation of VDR, calbindin-D28k, and calbindin-D9k suggested that the vitamin D signaling system was amplified by vitamin D and 17beta-estradiol. Vitamin D 136-145 S100 calcium binding protein G Rattus norvegicus 59-72 6430904-2 1984 A vitamin D-dependent Mr = 28,000 calcium-binding protein (CaBP) has been isolated from rat kidney. Vitamin D 2-11 S100 calcium binding protein G Rattus norvegicus 59-63 6204907-1 1984 A calcium binding protein (CaBP) with an apparent relative molecular weight of 28,000 was localized in the kidney of Anolis carolinensis with antisera directed against vitamin D-dependent CaBP from either rat kidney (RRCaBP) or chick intestine (CICaBP). Vitamin D 168-177 S100 calcium binding protein G Rattus norvegicus 27-31 6204907-1 1984 A calcium binding protein (CaBP) with an apparent relative molecular weight of 28,000 was localized in the kidney of Anolis carolinensis with antisera directed against vitamin D-dependent CaBP from either rat kidney (RRCaBP) or chick intestine (CICaBP). Vitamin D 168-177 S100 calcium binding protein G Rattus norvegicus 188-192 6602556-4 1983 The level of CaBP, the vitamin D-dependent cytosolic calcium-binding protein (Mr, approximately or equal to 9,000), corresponded to the magnitude of the saturable component. Vitamin D 23-32 S100 calcium binding protein G Rattus norvegicus 13-17 6163782-3 1981 The mouse protein had a molecular weight of approximately 10,000, exhibited cation-binding properties, and demonstrated immunologic identity with vitamin D-dependent rat CaBP. Vitamin D 146-155 S100 calcium binding protein G Rattus norvegicus 170-174 24077-6 1978 Although more lead bound to the higher molecular weight fraction and more calcium bound to the lower molecular weight vitamin D-induced CaBP, substantial amounts of lead and calcium were found in both fractions. Vitamin D 118-127 S100 calcium binding protein G Rattus norvegicus 136-140 1198113-1 1975 Treatment of duodenal tissue from rats deficient in vitamin D with 1,25-dihydroxy-vitamin D3 [1,25-(OH)2-D3] led to more than a doubling of calcium uptake by the isolated cells and the appearacne in those cells of previously undetectable calcium-binding protein (CaBP). Vitamin D 52-61 S100 calcium binding protein G Rattus norvegicus 263-267 1167739-1 1975 Analytical gel electrophoresis of the vitamin D-dependent intestinal calcium-binding protein (CaBP) has demonstrated two protein bands (1 and 2) of similar molecular weight and similar specific binding activity. Vitamin D 38-47 S100 calcium binding protein G Rattus norvegicus 94-98