PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3039857-2 1987 The analogue inhibited PTH-stimulated urinary excretion of phosphate and adenosine 3",5"-cyclic monophosphate in vitamin D-deficient thyroparathyroidectomized rats in a dose-dependent manner. Vitamin D 113-122 parathyroid hormone Rattus norvegicus 23-26 3771798-0 1986 Regulation by vitamin D metabolites of parathyroid hormone gene transcription in vivo in the rat. Vitamin D 14-23 parathyroid hormone Rattus norvegicus 39-58 3509783-2 1986 This study was undertaken to assess the possible direct, acute effects of vitamin D metabolites on PTH secretion in vitro. Vitamin D 74-83 parathyroid hormone Rattus norvegicus 99-102 3509783-9 1986 Parathyroid glands from -D rats incubated with 0.75 mM Ca secreted more PTH than glands of similar weight from rats given 25 micrograms vitamin D3 3 days earlier, suggesting that vitamin D or a metabolite of vitamin D may modulate the sensitivity of the parathyroid gland to medium Ca. Vitamin D 179-188 parathyroid hormone Rattus norvegicus 72-75 6689357-1 1983 The effect of graded nephron mass reduction by partial nephrectomy and the influence of parathyroid hormone and dietary phosphorus (P) on the production of 1,25-dihydroxy-vitamin D [1,25(OH)2D] were studied in vitamin D deficient rats. Vitamin D 171-180 parathyroid hormone Rattus norvegicus 88-107 3486118-7 1986 In vitamin D-sufficient animals, parathyroidectomy led to a 50% reduction in BMAR, which could be restored by treatment with PTH alone but not with 24,25-(OH)2D3. Vitamin D 3-12 parathyroid hormone Rattus norvegicus 125-128 3004922-1 1986 The in vivo effect of PTH on renal 24-hydroxylase activity of 25-hydroxyvitamin D3 (25OHD3) was examined in vitamin D-deficient thyroparathyroidectomized rats by a recently developed sensitive in vitro assay of 25OHD3-hydroxylases using rat kidney homogenates and by an in vivo assay measuring the accumulation of tritiated metabolites in plasma 5 h after injection of 25OH[3H]D3. Vitamin D 72-81 parathyroid hormone Rattus norvegicus 22-25 3840736-6 1985 Calcium infusions into hypocalcemic, vitamin D-deficient rats caused a fall in serum bioactive PTH concentrations to a mean of 13% of control values within 10 min. Vitamin D 37-46 parathyroid hormone Rattus norvegicus 95-98 6088011-1 1984 Studies presented here were designed to investigate further the basis for an impaired cAMP response to parathyroid hormone (PTH) in osteoblastlike calvarial bone cells isolated from vitamin D-deficient rat pups. Vitamin D 182-191 parathyroid hormone Rattus norvegicus 103-122 6688870-1 1983 To further characterize the mechanisms by which 25(OH) vitamin D3 (25(OH)D3) and 1.25(OH)2 vitamin D3 (1,25(OH)2D3) suppress the phosphaturic action of parathyroid hormone (PTH) we have studied the effects of cycloheximide (cyclohex), a protein synthesis inhibitor, on the interaction between PTH and vitamin D metabolites in parathyroidectomized (PTX) rats, both in vivo and in vitro experiments. Vitamin D 55-64 parathyroid hormone Rattus norvegicus 152-171 3508722-0 1986 Circulating parathyroid hormone concentrations in normal and vitamin D-deprived rat pups determined with an N-terminal-specific radioimmunoassay. Vitamin D 61-70 parathyroid hormone Rattus norvegicus 12-31 6435838-1 1984 The effect of vitamin D metabolites on parathyroid hormone secretion was studied using rat parathyroid gland cultured in basal medium Eagle containing 5% serum obtained from thyroparathyroidectomized rat, 1 mM magnesium, and calcium concentration varying from 0.75-2.25 mM, and radioimmunoassay for rat parathyroid hormone (rPTH). Vitamin D 14-23 parathyroid hormone Rattus norvegicus 39-58 6435838-3 1984 Comparison of dose-responses for inhibitory activity of some vitamin D metabolites on rPTH secretion showed: 1,25(OH)2D3 = 1,24,25(OH)3D3 greater than 1 alpha OHD3 greater than 25 OHD3. Vitamin D 61-70 parathyroid hormone Rattus norvegicus 86-90 6435838-5 1984 Analysis of structural activity relation of vitamin D metabolites studied indicated that 1 alpha or pseudo-1 alpha hydroxylated metabolites or analogs were active in inhibiting rPTH secretion, while, non-1 alpha hydroxylated metabolites were without or were weakly inhibitory only at very high concentrations. Vitamin D 44-53 parathyroid hormone Rattus norvegicus 177-181 6290192-2 1982 In vitamin D-fed rats, iv PTH as a bolus (10 USP units) elicited a phosphaturic response and an increase in urinary cAMP, whether or not the rats were thyroparathyroidectomized. Vitamin D 3-12 parathyroid hormone Rattus norvegicus 26-29 6290192-8 1982 (Bu)2cAMP infusion reproduced the paradoxical effect in vitamin D-fed, thyroparathyroidectomized rats receiving continuous infusion of PTH. Vitamin D 56-65 parathyroid hormone Rattus norvegicus 135-138 6254964-0 1980 Renal parathyroid hormone-dependent adenylate cyclase in vitamin D-deficient rats. Vitamin D 57-66 parathyroid hormone Rattus norvegicus 6-25 6687660-0 1983 Responsiveness of vitamin D-deficient fetal rat limb bones to parathyroid hormone in culture. Vitamin D 18-27 parathyroid hormone Rattus norvegicus 62-81 6687660-4 1983 The results suggest that the impaired calcemic response to parathyroid hormone seen in vitamin D-deficient animals in vivo is not the result of a specific unresponsiveness of vitamin D-deficient bone to parathyroid hormone. Vitamin D 87-96 parathyroid hormone Rattus norvegicus 59-78 7463073-1 1981 Rats fed diets deficient in calcium or vitamin D for 4 weeks displayed hypocalcemia, as indicated by a 50% reduction in serum calcium and a sevenfold elevation of serum parathyroid hormone. Vitamin D 39-48 parathyroid hormone Rattus norvegicus 169-188 6271531-1 1981 The regulatory role of vitamin D in bone formation and its interaction with parathyroid hormone (PTH) were analyzed in rats in vivo. Vitamin D 23-32 parathyroid hormone Rattus norvegicus 76-95 6255802-1 1980 This study reports the effects of the removal of endogenous PTH by thyroparathyroidectomy (TPTX) on the recovery of the reduced renal cAMP response to parathyroid hormone (PTH) in rats with chronically elevated PTH secondary to diets deficient in either vitamin D or calcium. Vitamin D 254-263 parathyroid hormone Rattus norvegicus 151-170 196836-1 1977 Teh stimulatory effect of parathyroid hormone (PTH) on renal 1alpha-hydroxylation of 25-hydroxyvitamin D3 (25-OH-D3) was studied in thyro-parathyroidectomized (TPTX), vitamin D-deficient rats into which bovine PTH, theophylline, cAMP or dibutyryl cAMP (dbcAMP) was constantly infused. Vitamin D 95-104 parathyroid hormone Rattus norvegicus 26-45 6253269-0 1980 Effects in vivo of vitamin D metabolites and 17 beta-estradiol on parathyroid hormone-dependent formation of adenosine 3",5"-monophosphate in rat bone. Vitamin D 19-28 parathyroid hormone Rattus norvegicus 66-85 6253269-1 1980 We used an in vivo infusion technique to assess the hypothesis that vitamin D metabolites and estrogens modulate tissue responsiveness to parathyroid hormone via effects on the adenylate cyclase-cAMP system. Vitamin D 68-77 parathyroid hormone Rattus norvegicus 138-157 6251904-0 1980 Renal parathyroid hormone-dependent adenylate cyclase activity after repletion of vitamin D-deficient rats with vitamin D-2. Vitamin D 82-91 parathyroid hormone Rattus norvegicus 6-25 6251904-1 1980 Rats fed a diet deficient in both vitamin D and Ca2+ exhibited a greater depression of the renal parathyroid hormone (PTH)-dependent adenylate cyclase than was observed in rats fed diets deficient in either vitamin D or calcium. Vitamin D 34-43 parathyroid hormone Rattus norvegicus 97-116 6252763-0 1980 Renal receptors for parathyroid hormone in normal, parathyroidectomized and vitamin D-deficient rats. Vitamin D 76-85 parathyroid hormone Rattus norvegicus 20-39 6249541-4 1980 These vitamin D derivatives also increased the PTH-degrading activity of kidney tissue when they were added in vitro. Vitamin D 6-15 parathyroid hormone Rattus norvegicus 47-50 6251904-1 1980 Rats fed a diet deficient in both vitamin D and Ca2+ exhibited a greater depression of the renal parathyroid hormone (PTH)-dependent adenylate cyclase than was observed in rats fed diets deficient in either vitamin D or calcium. Vitamin D 207-216 parathyroid hormone Rattus norvegicus 97-116 14421382-0 1959 [Indispensable role of vitamin D in demonstrating the hypercalcemic action of parathyroid hormone in the normal rat]. Vitamin D 23-32 parathyroid hormone Rattus norvegicus 78-97 4275650-0 1974 Influence of parathyroid hormone on ultrastructural and enzymatic changes induced by vitamin D in bone of thyroparathyroidectomized rats. Vitamin D 85-94 parathyroid hormone Rattus norvegicus 13-32 4340153-4 1972 It appears that the parathyroid hormone serves as a tropin for production of 1,25-dihydroxycholecalciferol, the hormonal form of vitamin D responsible for calcium mobilization from intestinal contents and bone. Vitamin D 129-138 parathyroid hormone Rattus norvegicus 20-39 25294851-8 2015 Importantly, in rat SHPT, the correction of vitamin D deficiency effectively reversed the resistance to paricalcitol induction of C/EBPbeta to suppress ADAM17 expression and PTG enlargement, reducing PTH by 50%. Vitamin D 44-53 parathyroid hormone Rattus norvegicus 200-203 5129305-8 1971 The resorptive response to hypophosphatemia, as previously shown for the resorptive response to excess endogenous parathyroid hormone, was partially inhibited by vitamin D deficiency. Vitamin D 162-171 parathyroid hormone Rattus norvegicus 114-133 27880946-2 2017 DP001 is an oral vitamin D analog that suppresses parathyroid hormone (PTH) in uremic rats, osteopenic women, and hemodialysis patients. Vitamin D 17-26 parathyroid hormone Rattus norvegicus 50-69 16261991-4 2005 Vitamin D supplementation stimulated intestinal calcium absorption with prevention of the abnormal elevation of serum PTH levels and prevented hypocalcemia in rats fed a low calcium diet, and stimulated intestinal calcium absorption in rats fed a normal calcium diet. Vitamin D 0-9 parathyroid hormone Rattus norvegicus 118-121 17720197-1 2007 BACKGROUND: Parathyroid hormone (PTH) replacement has been demonstrated to be superior to conventional treatment with calcium supplementation and vitamin D analogs for the treatment of hypoparathyroidism. Vitamin D 146-155 parathyroid hormone Rattus norvegicus 12-31 18156462-6 2008 RESULTS: Treatment with any of the vitamin D metabolites and 90-ET significantly decreased the serum intact-PTH level, but only the latter significantly decreased the serum Ca level. Vitamin D 35-44 parathyroid hormone Rattus norvegicus 108-111 18156462-9 2008 CONCLUSIONS: DI of vitamin D metabolites may be effective in controlling not only the PTH level, but also PTG hyperplasia, in advanced SHPT by, at least in part, apoptosis-induced cell death. Vitamin D 19-28 parathyroid hormone Rattus norvegicus 86-89 14646396-1 2004 OBJECTIVES: To compare the effects of vitamin D analogs versus calcitriol on serum levels of Ca, P and parathyroid hormone (PTH). Vitamin D 38-47 parathyroid hormone Rattus norvegicus 124-127 11502592-0 2001 Vitamin D reduces renal NaPi-2 in PTH-infused rats: complexity of vitamin D action on renal P(i) handling. Vitamin D 0-9 parathyroid hormone Rattus norvegicus 34-37 12778847-8 2003 The renal and bone PTH-R1 expression is upregulated in vitamin D deficient rats and by endotoxin, interleukin-2, dexamethasone, T3, and TGF beta. Vitamin D 55-64 parathyroid hormone Rattus norvegicus 19-22 12234297-1 2002 BACKGROUND: Calcitriol, 1,25-(OH)(2)D(3) (1,25D), the most active metabolite of vitamin D, has been used in the treatment of secondary hyperparathyroidism (SH) because it controls parathyroid gland growth and suppresses parathyroid hormone (PTH) synthesis and secretion. Vitamin D 80-89 parathyroid hormone Rattus norvegicus 220-239 12234297-1 2002 BACKGROUND: Calcitriol, 1,25-(OH)(2)D(3) (1,25D), the most active metabolite of vitamin D, has been used in the treatment of secondary hyperparathyroidism (SH) because it controls parathyroid gland growth and suppresses parathyroid hormone (PTH) synthesis and secretion. Vitamin D 80-89 parathyroid hormone Rattus norvegicus 241-244 11934649-2 2002 The results of our previous animal studies have suggested that the therapeutic effect of active vitamin D on bone loss after estrogen deficiency can be dissociated at least partly from its effect of enhancing intestinal calcium absorption and suppressing parathyroid hormone (PTH) secretion. Vitamin D 96-105 parathyroid hormone Rattus norvegicus 255-274 11305809-5 2000 RESULTS: The main findings were: amelioration of 1,25(OH)2D3-induced hypercalcemia by 24,25(OH)2D3, and similar suppression of PTH by the two metabolites of vitamin D when administered alone or in combination. Vitamin D 157-166 parathyroid hormone Rattus norvegicus 127-130 11019490-5 2000 The amount of PiT-1 mRNA in the parathyroid is controlled by vitamin D and dietary Pi, which are the most important regulators of PTH secretion. Vitamin D 61-70 parathyroid hormone Rattus norvegicus 130-133 9808142-1 1998 The active metabolite of vitamin D, calcitriol [1,25(OH)2D3] suppresses parathyroid hormone (PTH) gene transcription and PTH secretion. Vitamin D 25-34 parathyroid hormone Rattus norvegicus 72-91 10662728-4 2000 Vitamin D-deficient, thyroparathyrodectomized rats had lower serum and higher urinary calcium concentrations compared with control animals as well as lower serum PTH and calcitonin concentrations. Vitamin D 0-9 parathyroid hormone Rattus norvegicus 162-165 10662728-6 2000 ClC-5 mRNA and protein expression increase near to control levels in vitamin D-deficient, thyroparathyroidectomized rats injected with PTH. Vitamin D 69-78 parathyroid hormone Rattus norvegicus 135-138 10571682-0 1999 Vitamin D receptor interactions with the rat parathyroid hormone gene: synergistic effects between two negative vitamin D response elements. Vitamin D 112-121 parathyroid hormone Rattus norvegicus 45-64 10571682-1 1999 Vitamin D response elements (VDREs) that are required for negative regulation of rat parathyroid hormone (rPTH) gene expression have been characterized. Vitamin D 0-9 parathyroid hormone Rattus norvegicus 85-104 10571682-1 1999 Vitamin D response elements (VDREs) that are required for negative regulation of rat parathyroid hormone (rPTH) gene expression have been characterized. Vitamin D 0-9 parathyroid hormone Rattus norvegicus 106-110 10633456-0 1999 Regulation of the parathyroid hormone gene by vitamin D, calcium and phosphate. Vitamin D 46-55 parathyroid hormone Rattus norvegicus 18-37 9799830-0 1998 Gastric fundectomy in the rat: effects on mineral and bone metabolism, with emphasis on the gastrin-calcitonin-parathyroid hormone-vitamin D axis. Vitamin D 131-140 parathyroid hormone Rattus norvegicus 111-130 9717845-0 1998 Calreticulin inhibits vitamin D"s action on the PTH gene in vitro and may prevent vitamin D"s effect in vivo in hypocalcemic rats. Vitamin D 22-31 parathyroid hormone Rattus norvegicus 48-51 8918622-2 1996 We tested three new vitamin D analogues (CB 1093, EB 1213, GS 1725) in an attempt to identify potentially non hypercalcaemic compounds, capable of decreasing plasma parathyroid hormone (PTH) concentration. Vitamin D 20-29 parathyroid hormone Rattus norvegicus 165-184 9165035-0 1997 Parathyroid hormone increases bone formation and improves mineral balance in vitamin D-deficient female rats. Vitamin D 77-86 parathyroid hormone Rattus norvegicus 0-19 9165035-1 1997 The present study was designed to investigate whether enhanced bone formation due to intermittent PTH administration is dependent on vitamin D metabolites. Vitamin D 133-142 parathyroid hormone Rattus norvegicus 98-101 9165035-14 1997 Furthermore, PTH may have a vitamin D-dependent influence on intestinal magnesium absorption. Vitamin D 28-37 parathyroid hormone Rattus norvegicus 13-16 9165035-15 1997 Finally, short term PTH treatment is anabolic in bone of vitamin D-deficient rats when adequate mineral amounts are provided in the diet. Vitamin D 57-66 parathyroid hormone Rattus norvegicus 20-23 8840303-1 1996 The main factors which regulate parathyroid hormone (PTH) production are calcium, phosphate, vitamin D and the sex steroids, estrogens and progestagins. Vitamin D 93-102 parathyroid hormone Rattus norvegicus 32-51 8792407-1 1996 The main factors which regulate parathyroid hormone (PTH) production are calcium, phosphate, vitamin D, and estrogens. Vitamin D 93-102 parathyroid hormone Rattus norvegicus 32-51 8792407-1 1996 The main factors which regulate parathyroid hormone (PTH) production are calcium, phosphate, vitamin D, and estrogens. Vitamin D 93-102 parathyroid hormone Rattus norvegicus 53-56 8840303-1 1996 The main factors which regulate parathyroid hormone (PTH) production are calcium, phosphate, vitamin D and the sex steroids, estrogens and progestagins. Vitamin D 93-102 parathyroid hormone Rattus norvegicus 53-56 7649081-0 1995 Parathyroid hormone (PTH)/PTH-related protein receptor messenger ribonucleic acid expression and PTH response in a rat model of secondary hyperparathyroidism associated with vitamin D deficiency. Vitamin D 174-183 parathyroid hormone Rattus norvegicus 0-19 7485144-1 1995 The active metabolite of vitamin D, calcitriol (1 alpha,25-(OH)2D3), suppresses parathyroid hormone (PTH) gene transcription. Vitamin D 25-34 parathyroid hormone Rattus norvegicus 80-99 7485144-1 1995 The active metabolite of vitamin D, calcitriol (1 alpha,25-(OH)2D3), suppresses parathyroid hormone (PTH) gene transcription. Vitamin D 25-34 parathyroid hormone Rattus norvegicus 101-104 7649081-1 1995 The aim of the present work was to characterize at the molecular level the mechanism of PTH resistance in a rat model of secondary hyperparathyroidism resulting from vitamin D deprivation. Vitamin D 166-175 parathyroid hormone Rattus norvegicus 88-91 7649081-11 1995 Normalization of PTH/PTHrp receptor mRNA expression was observed after vitamin D supplementation (D-D+ rats), but not after correction of the hypocalcemia and secondary hyperparathyroidism by oral lactose and calcium supplementation. Vitamin D 71-80 parathyroid hormone Rattus norvegicus 17-20 7649081-12 1995 In the epi/metaphysis, an approximately 2-fold increase in PTH/PTHrp receptor mRNA was also observed in the D-D- rats compared to the controls; this increase was partially corrected upon normalization of the calcemia and PTH levels with either vitamin D (D-D+ group) or lactose/calcium (D-Ca+ group). Vitamin D 244-253 parathyroid hormone Rattus norvegicus 59-62 2173326-3 1990 PTH suppressed the Ca2+ pump activity in normocalcemic vitamin D-deficient rats. Vitamin D 55-64 parathyroid hormone Rattus norvegicus 0-3 8274878-1 1993 We tested whether the protein kinase C (PKC) modulation of PTH-sensitive adenylate cyclase in ROS 17/2.8 cells is affected by the glucocorticoid dexamethasone and the vitamin D hormone 1,25-dihydroxyvitamin D3 [1,25(OH)2D3]. Vitamin D 167-176 parathyroid hormone Rattus norvegicus 59-62 1597134-1 1992 1,25-Dihydroxyvitamin D3 (1,25D) regulates its own levels in circulation by affecting its rates of synthesis and degradation, 22-Oxacalcitriol (OCT), a vitamin D analog with low calcemic activity, decreases circulating PTH levels, one of the regulators of renal 1 alpha-hydroxylase, and stimulates vitamin D degradation in vitro. Vitamin D 14-23 parathyroid hormone Rattus norvegicus 219-222 1570767-9 1992 Levels in parathyroidectomized (PTX) rats (n = 9) were undetectable, but renal insufficiency and vitamin D deficiency increased PTH to 587.4 +/- 141.3 pg/ml (n = 73) and 1662.0 +/- 137.8 (n = 27), respectively. Vitamin D 97-106 parathyroid hormone Rattus norvegicus 128-131 2067203-7 1991 A synthetic analogue of vitamin D, 22-oxa-1,25(OH)2D3, also suppressed PTH mRNA to normal levels, but without hypercalcemia. Vitamin D 24-33 parathyroid hormone Rattus norvegicus 71-74 8396012-13 1993 Furthermore, comparison of the transient elevation of calcium absorption by OCT with its more prolonged effects on PTH and calbindin D9k indicates that each action of vitamin D compounds has a distinct biological half-life. Vitamin D 167-176 parathyroid hormone Rattus norvegicus 115-118 1492397-3 1992 Neonates, being born by these females with the nephrectomy, had vitamin D deficiency, which was manifested as a decrease in content of active vitamin D metabolites and minerals as well as an increase in activity of alkaline phosphatase and in the content of parathyroid hormone. Vitamin D 64-73 parathyroid hormone Rattus norvegicus 258-277 3071395-0 1988 Effect of long-term and short-term diabetes on the parathyroid hormone sensitive rat renal adenylate cyclase: correlation with vitamin D metabolism. Vitamin D 127-136 parathyroid hormone Rattus norvegicus 51-70 2212016-0 1990 Regulation of parathyroid hormone gene expression by hypocalcemia, hypercalcemia, and vitamin D in the rat. Vitamin D 86-95 parathyroid hormone Rattus norvegicus 14-33 2212016-2 1990 We now report the effect of 3 and 8 wk of changes in dietary vitamin D and calcium on PTH mRNA levels. Vitamin D 61-70 parathyroid hormone Rattus norvegicus 86-89 2212016-3 1990 PTH mRNA levels were increased by 3 wk of calcium deficiency (five times), a vitamin D-deficient diet (two times), and combined deficiency (10 times), but not changed by high calcium. Vitamin D 77-86 parathyroid hormone Rattus norvegicus 0-3 2212016-4 1990 Vitamin D-deficient-diet rats" PTH mRNA did not decrease after a single large dose of 1,25(OH)2D3, but did decrease partially after repeated daily doses of 1,25(OH)2D3. Vitamin D 0-9 parathyroid hormone Rattus norvegicus 31-34 2212016-8 1990 Moreover, a calcium-deficient, more so than a vitamin D-deficient diet, amplifies the expression of the PTH gene, and vitamin D is necessary for an intact response of PTH mRNA to 1,25(OH)2D3 or calcium. Vitamin D 46-55 parathyroid hormone Rattus norvegicus 104-107 2212016-8 1990 Moreover, a calcium-deficient, more so than a vitamin D-deficient diet, amplifies the expression of the PTH gene, and vitamin D is necessary for an intact response of PTH mRNA to 1,25(OH)2D3 or calcium. Vitamin D 118-127 parathyroid hormone Rattus norvegicus 167-170 2848683-4 1988 Renal membranes of vitamin D-deficient rats with secondary hyperparathyroidism had a reduced PLP-stimulated as well as PTH-stimulated adenylate cyclase response. Vitamin D 19-28 parathyroid hormone Rattus norvegicus 119-122 3213628-6 1988 To assess the effect of oxidation on the ability of PTH to inhibit the production of the 24,25-dihydroxyvitamin D3 (24,25(OH)2D3), the infusion protocol was performed in vitamin D-deficient rats repleted with 1,25(OH)2D3 by injection. Vitamin D 104-113 parathyroid hormone Rattus norvegicus 52-55 2850724-0 1988 Certain vitamin D metabolites potentiate the expression of parathyroid hormone bioactivity. Vitamin D 8-17 parathyroid hormone Rattus norvegicus 59-78 2834176-0 1988 Parathyroid hormone desensitization in renal membranes of vitamin D-deficient rats is associated with a postreceptor defect. Vitamin D 58-67 parathyroid hormone Rattus norvegicus 0-19 2834176-1 1988 We examined the characteristics of PTH resistance in vitamin D-deficient rats employing renal membranes in vitro. Vitamin D 53-62 parathyroid hormone Rattus norvegicus 35-38 2834176-8 1988 The results suggest that a major contribution to PTH resistance in vitamin D-deficient animals is a postreceptor defect at the level of the G proteins and that this defect is manifest only in tissue expressing the PTH receptor. Vitamin D 67-76 parathyroid hormone Rattus norvegicus 49-52 2834176-8 1988 The results suggest that a major contribution to PTH resistance in vitamin D-deficient animals is a postreceptor defect at the level of the G proteins and that this defect is manifest only in tissue expressing the PTH receptor. Vitamin D 67-76 parathyroid hormone Rattus norvegicus 214-217 3348387-3 1988 In the present work, the role of PTH was assessed by studying the influence of 1-hydroxypentane-1,1-bisphosphonate (HPeBP) on vitamin D and Ca metabolism in both intact and thyroparathyroidectomized (TPTX) rats. Vitamin D 126-135 parathyroid hormone Rattus norvegicus 33-36