PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26748441-4	2016	Here we report high to medium resolution structures of native porcine RNase 4 (PL3), a "substrate-specificity" determining mutant D80A and their respective complexes with deoxyuridine 5"-monophosphate (dUMP) and deoxycytidine 5"-monophosphate (dCMP).	Deoxycytidine Monophosphate	212-242	ribonuclease A family member 4	Homo sapiens	70-77	
26748441-4	2016	Here we report high to medium resolution structures of native porcine RNase 4 (PL3), a "substrate-specificity" determining mutant D80A and their respective complexes with deoxyuridine 5"-monophosphate (dUMP) and deoxycytidine 5"-monophosphate (dCMP).	Deoxycytidine Monophosphate	244-248	ribonuclease A family member 4	Homo sapiens	70-77	
26748441-5	2016	These structures provide insight into the structural basis of the uridine versus cytosine substrate specificity in RNase 4: in the D80A mutant (D80A dCMP), the side chain of Arg101 is positioned further away from the substrate-binding pocket due to the loss of the Asp80 side chain, reducing the repulsion force on the less favoured dCMP from Arg101 and allowing the ligand to occupy the binding pocket.	Deoxycytidine Monophosphate	149-153	ribonuclease A family member 4	Homo sapiens	115-122	
26748441-5	2016	These structures provide insight into the structural basis of the uridine versus cytosine substrate specificity in RNase 4: in the D80A mutant (D80A dCMP), the side chain of Arg101 is positioned further away from the substrate-binding pocket due to the loss of the Asp80 side chain, reducing the repulsion force on the less favoured dCMP from Arg101 and allowing the ligand to occupy the binding pocket.	Deoxycytidine Monophosphate	333-337	ribonuclease A family member 4	Homo sapiens	115-122