PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27081671-8 2016 Overexpression of StAR in mouse RAW 264.7 macrophages increased the effects of both all-trans retinoic acid (atRA) and 9-cis RA on cholesterol efflux, suggesting StAR enhances the efficacy of retinoic acid receptor (RAR) and/or retinoid X receptor (RXR) ligands. Radium 32-34 retinoic acid receptor, alpha Mus musculus 192-214 27081671-8 2016 Overexpression of StAR in mouse RAW 264.7 macrophages increased the effects of both all-trans retinoic acid (atRA) and 9-cis RA on cholesterol efflux, suggesting StAR enhances the efficacy of retinoic acid receptor (RAR) and/or retinoid X receptor (RXR) ligands. Radium 32-34 retinoic acid receptor, alpha Mus musculus 216-219 12223961-1 2002 The active metabolite of vitamin A (retinoic acid, RA) acts through the nuclear receptors RARalpha, beta and gamma and RXRalpha, beta and gamma. Radium 51-53 retinoic acid receptor, alpha Mus musculus 90-98 25897113-6 2015 Our data offer an unprecedentedly detailed view on the action of RA in triggering pluripotent cell differentiation and demonstrate that RAR/RXR action is mediated via two different sets of regulatory regions tightly associated with cell differentiation status. Radium 65-67 retinoic acid receptor, alpha Mus musculus 136-139 23744644-5 2013 RA activity was abrogated by an antagonist of the RAR. Radium 0-2 retinoic acid receptor, alpha Mus musculus 50-53 23744644-8 2013 These results suggest that RA selectively induces IgA isotype switching through RAR and that RA and TGF-beta have important effects on the overall gut IgA antibody response. Radium 27-29 retinoic acid receptor, alpha Mus musculus 80-83 22661711-8 2012 The differential ability of RAR-RXR bound to DR0 compared to DR2, DR5, and DR8 to mediate RA-dependent transcriptional activation indicates that half-site spacing allosterically regulates RAR function. Radium 28-30 retinoic acid receptor, alpha Mus musculus 188-191 17613434-4 2007 In RA-treated PML/RARA-transformed cells, the absence of RXR binding results in monocytic, rather than granulocytic, differentiation. Radium 3-5 retinoic acid receptor, alpha Mus musculus 18-22 19381305-6 2009 As reviewed here, the generation of such germline mutations, combined with pharmacological approaches to block the RA signalling pathway, has provided genetic evidence that RAR/RXR heterodimers are indeed the functional units transducing the RA signal during prenatal development. Radium 115-117 retinoic acid receptor, alpha Mus musculus 173-176 10397747-6 1999 Pharmacological doses of RA induced differentiation and inhibited proliferation of cells transformed with either of the APL fusion genes, including PLZF-RARalpha, whereas physiological retinoic acid concentrations were sufficient to reverse the phenotype of cells transformed with wild-type RARalpha. Radium 25-27 retinoic acid receptor, alpha Mus musculus 153-161 10397747-6 1999 Pharmacological doses of RA induced differentiation and inhibited proliferation of cells transformed with either of the APL fusion genes, including PLZF-RARalpha, whereas physiological retinoic acid concentrations were sufficient to reverse the phenotype of cells transformed with wild-type RARalpha. Radium 25-27 retinoic acid receptor, alpha Mus musculus 291-299 10393558-6 1999 The IR0-containing reporter was induced by RA in COS-1 cells in the presence of exogenously provided RARalpha and RXRbeta. Radium 43-45 retinoic acid receptor, alpha Mus musculus 101-109 7615548-8 1995 Accordingly, we also find that 9-cis RA, which activates both RAR and RXR, is a more potent inducer of the RAR beta gene than RA, which only activates RAR. Radium 37-39 retinoic acid receptor, alpha Mus musculus 62-65 7615548-8 1995 Accordingly, we also find that 9-cis RA, which activates both RAR and RXR, is a more potent inducer of the RAR beta gene than RA, which only activates RAR. Radium 37-39 retinoic acid receptor, alpha Mus musculus 107-110 33902658-9 2021 Our results suggest that the inhibition of RARalphaS77 phosphorylation by either expressing RARalphaS77A or inhibiting RARalpha"s phosphokinase CDK7, can bypass RA stimuli to transactivate tumor-suppressive miR-3074-5p and reduce oncogenic DHRS3, thus overcoming the RA-resistance of TNBC. Radium 92-94 retinoic acid receptor, alpha Mus musculus 43-51 8832901-4 1995 However, in these cells Oct-4 promoter repression can be rescued in a RA-dependent manner by cotransfection of RAR alpha 2 or RAR beta 2 but not RARr gamma 1, matching previously reported transactivation properties of these receptor types. Radium 70-72 retinoic acid receptor, alpha Mus musculus 111-114 8832901-4 1995 However, in these cells Oct-4 promoter repression can be rescued in a RA-dependent manner by cotransfection of RAR alpha 2 or RAR beta 2 but not RARr gamma 1, matching previously reported transactivation properties of these receptor types. Radium 70-72 retinoic acid receptor, alpha Mus musculus 126-129