PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28855513-4 2017 In this biosensor, two inactive luciferase fragments are sandwiched by Raf-1, whose conformation changes upon GTP-Ras binding. Radium 114-117 Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens 71-76 10205168-5 1999 Raf-1 that cannot interact with Ras-GTP is not phosphorylated, showing that phosphorylation is Ras dependent, presumably occurring at the plasma membrane. Radium 32-35 Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens 0-5 21862573-0 2011 Activation kinetics of RAF protein in the ternary complex of RAF, RAS-GTP, and kinase on the plasma membrane of living cells: single-molecule imaging analysis. Radium 66-69 Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens 23-26 25663768-10 2015 In addition, pre-miR-21-LV or siRASA1 (down-regulation of RASA1) cells showed higher cell proliferation, reduced apoptosis, increased expression of RAS-GTP, p-AKT, Raf-1, KRAS, and p-ERK1/2, and higher invasion and tumor formation ability, compared with control, anti-miR-21-LV or pcDNA3.1-RASA1 (up-regulation of RASA1) cells (P < 0.05). Radium 32-35 Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens 164-169 17064357-9 2006 Based on these findings, we speculate that Raf-1 is activated to effectively mediate Ras-dependent signals in Alzheimer"s disease. Radium 85-88 Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens 43-48 15711535-0 2005 Ras binding opens c-Raf to expose the docking site for mitogen-activated protein kinase kinase. Radium 0-3 Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens 18-23