PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8911995-1 1996 The polygenic predisposition to RA is conferred particularly by disease susceptibility sequences in the HVR3 of HLA DRB1 present in those subtypes of DR4 and DR1 that are associated with RA. Radium 32-34 major histocompatibility complex, class II, DR beta 4 Homo sapiens 150-153 11396094-2 2001 Analysis of the structural interactions between DR4 susceptibility molecules and T cells specific for the peptide-MHC complex suggests a mechanism for directed T-cell selection and amplification in which RA-associated genetic polymorphisms bias intermolecular recognition. Radium 204-206 major histocompatibility complex, class II, DR beta 4 Homo sapiens 48-51 8911995-1 1996 The polygenic predisposition to RA is conferred particularly by disease susceptibility sequences in the HVR3 of HLA DRB1 present in those subtypes of DR4 and DR1 that are associated with RA. Radium 187-189 major histocompatibility complex, class II, DR beta 4 Homo sapiens 150-153 7987717-2 1994 The results showed that the DR4 was significantly associated with RA(RR = 3.1, chi 2 = 13.8, P < 0.005). Radium 66-68 major histocompatibility complex, class II, DR beta 4 Homo sapiens 28-31 8835242-6 1995 In DR4+ RA patients, we observed a higher PRL peak at 60 min. Radium 8-10 major histocompatibility complex, class II, DR beta 4 Homo sapiens 3-6 8835242-10 1995 In DR4+ RA patients, the overall prolactin secretion reflected by the AUC is increased compared to DR4- patients. Radium 8-10 major histocompatibility complex, class II, DR beta 4 Homo sapiens 99-102 9157087-11 1996 A heterogenous association of DQB1 alleles with DR4 subtypes, influencing susceptibility to RA, suggests the DQB locus is not primarily associated with RA and susceptibility lies in the sequence 67-74 of the DRB1 loci. Radium 92-94 major histocompatibility complex, class II, DR beta 4 Homo sapiens 48-51 7987717-10 1994 The different DR4 subtype structures and frequencies may account for the different associations of DR4 with RA in various ethnic groups. Radium 108-110 major histocompatibility complex, class II, DR beta 4 Homo sapiens 14-17 7987717-10 1994 The different DR4 subtype structures and frequencies may account for the different associations of DR4 with RA in various ethnic groups. Radium 108-110 major histocompatibility complex, class II, DR beta 4 Homo sapiens 99-102 7519185-7 1994 Comparison of reaction patterns with amino acid sequences suggest that the antibodies against subtypes of DR4 are specific primarily for a region containing sequences postulated to determine susceptibility to RA. Radium 209-211 major histocompatibility complex, class II, DR beta 4 Homo sapiens 106-109 3067866-7 1988 Genes on chromosome 14 may also influence susceptibility to RA, probably by interaction with MHC genes and there are different Gm associations for DR4-positive and collagen-antibody-positive rheumatoid subgroups. Radium 60-62 major histocompatibility complex, class II, DR beta 4 Homo sapiens 147-150