PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1822394-11 1991 It appears that the efficacy of all-trans RA is the resultant of multiple parameters (RA concentration, ratio of PML/RAR alpha transcripts to normal RAR alpha, CRABP) which need to be defined to efficiently monitor all-trans RA therapy in APL. Radium 42-44 cellular retinoic acid binding protein 1 Homo sapiens 160-165 8207983-9 1994 This induced ATRA hypercatabolytic state should be monitored during consolidation therapy and at relapse by evaluating CRABP and RA metabolite levels, in order to detect ATRA resistance in patients with AML3. Radium 15-17 cellular retinoic acid binding protein 1 Homo sapiens 119-124 1316927-5 1992 FPLC analysis also demonstrated a 15-kDa peak of specific RA binding activity, consistent with the presence of cellular retinoic acid binding protein (CRABP). Radium 58-60 cellular retinoic acid binding protein 1 Homo sapiens 111-149 1316927-5 1992 FPLC analysis also demonstrated a 15-kDa peak of specific RA binding activity, consistent with the presence of cellular retinoic acid binding protein (CRABP). Radium 58-60 cellular retinoic acid binding protein 1 Homo sapiens 151-156 11266607-2 2001 This report describes a novel photoaffinity-based binding assay involving competition between potential ligands of CRABP and [(3)H]atRA or [(3)H]-9-cis-RA for binding to the atRA-binding sites of CRABP I and II. Radium 116-118 cellular retinoic acid binding protein 1 Homo sapiens 196-210 7815831-9 1994 This induced ATRA hypercatabolytic state should be monitored during consolidation therapy and at relapse by evaluating CRABP and RA metabolite levels, in order to detect ATRA resistance in patients with AML3. Radium 15-17 cellular retinoic acid binding protein 1 Homo sapiens 119-124 1328234-5 1992 Moreover, the level of CRABP-I determines the rate of RA metabolism to 4-oxo-RA such that the higher the CRABP-I level, the faster the metabolism of [3H]retinoic acid. Radium 24-26 cellular retinoic acid binding protein 1 Homo sapiens 105-112 2190176-4 1990 In the development of the limb bud, RA has been proposed as a morphogen controlling development via a concentration gradient established by a mechanism thought to involve specific nuclear receptors and a cytosolic binding protein (CRABP). Radium 36-38 cellular retinoic acid binding protein 1 Homo sapiens 231-236 6299278-1 1982 Cellular retinoic acid-binding protein (CRABP) was detected in the nuclear fraction of N-methyl-N-nitrosourea-induced mammary cancers after the incubation of cytosol containing [3H]retinoic acid (RA)-bound CRABP with isolated nuclei. Radium 41-43 cellular retinoic acid binding protein 1 Homo sapiens 0-38 6299278-1 1982 Cellular retinoic acid-binding protein (CRABP) was detected in the nuclear fraction of N-methyl-N-nitrosourea-induced mammary cancers after the incubation of cytosol containing [3H]retinoic acid (RA)-bound CRABP with isolated nuclei. Radium 41-43 cellular retinoic acid binding protein 1 Homo sapiens 206-211 6299278-3 1982 [3H]RA-CRABP was found to be a prerequisite for the detection of nuclear binding, since the incubation of isolated nuclei or 0.4 M-KCl extract of the nuclei with [3H]RA did not result in any significant binding. Radium 4-6 cellular retinoic acid binding protein 1 Homo sapiens 7-12