PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20833643-3 2010 ACPA-positive RA was found to be associated with the HLA-DR shared epitope (SE), but ACPA negative was not. Radium 14-16 proteinase 3 Homo sapiens 0-4 23287363-12 2013 CONCLUSION: Alcohol intake is inversely associated with ACPA-positive RA, suggesting a protective effect. Radium 70-72 proteinase 3 Homo sapiens 56-60 20833643-8 2010 RESULTS: ACPA-negative RA with apparent bone erosion was not associated with SE, supporting the idea that ACPA-negative RA is genetically distinct from ACPA-positive RA. Radium 23-25 proteinase 3 Homo sapiens 9-13 20833643-10 2010 In accordance with the ACPA-negative RA subset, the RF-negative RA subset showed a clearly distinct pattern of association with SE from the RF-positive RA. Radium 37-39 proteinase 3 Homo sapiens 23-27 20833643-12 2010 CONCLUSIONS: ACPA-negative erosive RA is genetically distinct from ACPA-positive RA. Radium 35-37 proteinase 3 Homo sapiens 13-17 20833643-4 2010 However, the suspicion remained that this result was caused by the ACPA-negative RA subset containing patients with non-RA diseases. Radium 81-83 proteinase 3 Homo sapiens 67-71 20833643-4 2010 However, the suspicion remained that this result was caused by the ACPA-negative RA subset containing patients with non-RA diseases. Radium 120-122 proteinase 3 Homo sapiens 67-71 31160794-0 2019 ACPA-negative RA divided into clinical subsets. Radium 14-16 proteinase 3 Homo sapiens 0-4 31464042-5 2020 RESULTS: Pre-RA autoantibody levels were elevated in cases vs. controls as follows: ACPA-IgG 17.9 years, RF-IgA 14.2 years, RF-IgM 7.2 years, ACPA-IgA 6.2 years and ACPA-IgM and RF-IgA both at 5.0 years (p<0.01, all comparisons). Radium 13-15 proteinase 3 Homo sapiens 84-88 31081041-10 2019 CONCLUSION: The results of the epigenetic qPCR assay showed that low levels of Th17 cells were predictive of developing RA, particularly in the ACPA-negative patients. Radium 120-122 proteinase 3 Homo sapiens 144-148 24831057-3 2014 This process in the gums appears to be independent of smoking, the main environmental risk factor for ACPA-positive RA. Radium 116-118 proteinase 3 Homo sapiens 102-106 28660910-0 2017 Rheumatoid arthritis: ACPA status influences RA development. Radium 45-47 proteinase 3 Homo sapiens 22-26 26983453-8 2016 When combining the discovery and validation cohorts, an intronic SNP in the Solute Carrier family 8 gene (SLC8A3) was found to be associated with ACPA-positive RA at a genome-wide level of significance RA [odds ratio (95% CI): 1.42 (1.25, 1.6), Pcombined = 3.19x10(-8)]. Radium 160-162 proteinase 3 Homo sapiens 146-150