PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8518741-4 1993 The induction process is concomitant with that of cytochrome P-450-IVA1 and cytosolic epoxide hydrolase, which, like bilirubin UGT, are mainly involved in the metabolism of endogenous substrates. Bilirubin 117-126 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 50-71 15382119-2 2004 At the hepatic level, the orphan nuclear constitutive androstane receptor (CAR) (NR1I3) controls phase I (cytochrome P450 [CYP] 2B and CYP3A), phase II (UGT1A1), and transporter (SLC21A6, MRP2) genes involved in drug metabolism and bilirubin clearance in response to xenobiotics such as phenobarbital or endobiotics such as bilirubin. Bilirubin 232-241 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 106-130 16541400-0 2006 Bilirubin degradation by uncoupled cytochrome P450. Bilirubin 0-9 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 35-50 16541400-3 2006 Degradation of bilirubin takes place (a) on interaction with oxidative free radicals and (b) when cytochrome P450 (CYP) enzymes are uncoupled by polyhalogenated substrate analogues. Bilirubin 15-24 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 98-113 16541400-3 2006 Degradation of bilirubin takes place (a) on interaction with oxidative free radicals and (b) when cytochrome P450 (CYP) enzymes are uncoupled by polyhalogenated substrate analogues. Bilirubin 15-24 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 115-118 15382119-2 2004 At the hepatic level, the orphan nuclear constitutive androstane receptor (CAR) (NR1I3) controls phase I (cytochrome P450 [CYP] 2B and CYP3A), phase II (UGT1A1), and transporter (SLC21A6, MRP2) genes involved in drug metabolism and bilirubin clearance in response to xenobiotics such as phenobarbital or endobiotics such as bilirubin. Bilirubin 324-333 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 106-130