PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10895987-0	2000	Inhibitory effects of silibinin on cytochrome P-450 enzymes in human liver microsomes.	Silybin	22-31	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	35-51	
10895987-1	2000	Silibinin, the main constituent of silymarin, a flavonoid drug from silybum marianum used in liver disease, was tested for inhibition of human cytochrome P-450 enzymes.	Silybin	0-9	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	143-159	
2155989-4	1990	These results suggest that the dose-dependent dual effect of silibinin on corticosteroid secretion may be attributed to corresponding changes in the activities of cytochrome P-450 enzymes, and that stimulation of ACTH-induced corticosteroidogenesis by silibinin is presumably due to the antioxidant property of the drug.	Silybin	61-70	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	163-179