PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25288725-2	2014	The family of CBL-interacting protein kinases (CIPK) and their interacting activators, the calcium sensors calcineurin B-like (CBLs), work together to decode calcium signals elicited by stress situations.	Chlorambucil	127-131	Cbl proto-oncogene	Homo sapiens	14-17	
32262232-0	2015	Coumarin-benzothiazole-chlorambucil (Cou-Benz-Cbl) conjugate: an ESIPT based pH sensitive photoresponsive drug delivery system.	Chlorambucil	23-35	Cbl proto-oncogene	Homo sapiens	46-49	
32262232-1	2015	We have developed an ESIPT based drug delivery system (DDS), Cou-Benz-Cbl conjugate, by incorporating a benzothiazole group at the 8th position of the 7-hydroxy-coumarin moiety for pH sensitive fluorescence properties and photocontrolled release of the anticancer drug chlorambucil.	Chlorambucil	269-281	Cbl proto-oncogene	Homo sapiens	70-73	
32262232-5	2015	Photolysis of the Cou-Benz-Cbl conjugate using UV light of wavelength >=365 nm resulted in the efficient release of the anticancer drug chlorambucil.	Chlorambucil	136-148	Cbl proto-oncogene	Homo sapiens	27-30	
32262232-7	2015	Further, an MTT assay showed that the Cou-Benz-Cbl conjugate has a good biocompatibility and low cytotoxicity towards the MDA-MB-231 cell line, whereas upon exposure to UV light, the Cou-Benz-Cbl conjugate exhibited enhanced cytotoxicity compared to the free drug due to the effective release of the anticancer drug chlorambucil inside the cancer cell.	Chlorambucil	316-328	Cbl proto-oncogene	Homo sapiens	47-50	
32262232-7	2015	Further, an MTT assay showed that the Cou-Benz-Cbl conjugate has a good biocompatibility and low cytotoxicity towards the MDA-MB-231 cell line, whereas upon exposure to UV light, the Cou-Benz-Cbl conjugate exhibited enhanced cytotoxicity compared to the free drug due to the effective release of the anticancer drug chlorambucil inside the cancer cell.	Chlorambucil	316-328	Cbl proto-oncogene	Homo sapiens	192-195	
25994134-2	2015	Formyl-Cbl, acetyl-Cbl, and propionyl-Cbl were decomposed by a NH2OH treatment, forming formo-, aceto-, and propionohydroxamic acids, respectively, which offers a proof for the presence of "activated" acyl groups and for their structures of Co-acyl-Cbls.	Chlorambucil	248-253	Cbl proto-oncogene	Homo sapiens	7-10	
25994134-2	2015	Formyl-Cbl, acetyl-Cbl, and propionyl-Cbl were decomposed by a NH2OH treatment, forming formo-, aceto-, and propionohydroxamic acids, respectively, which offers a proof for the presence of "activated" acyl groups and for their structures of Co-acyl-Cbls.	Chlorambucil	248-253	Cbl proto-oncogene	Homo sapiens	19-22	
25994134-2	2015	Formyl-Cbl, acetyl-Cbl, and propionyl-Cbl were decomposed by a NH2OH treatment, forming formo-, aceto-, and propionohydroxamic acids, respectively, which offers a proof for the presence of "activated" acyl groups and for their structures of Co-acyl-Cbls.	Chlorambucil	248-253	Cbl proto-oncogene	Homo sapiens	19-22	
32720950-1	2020	We report a two-photon responsive drug delivery system (DDS), namely, p-hydroxyphenacyl-naphthalene-chlorambucil (pHP-Naph-Cbl), having a two-photon absorption (TPA) cross-section of >=20 GM in the phototherapeutic window (700 nm).	Chlorambucil	100-112	Cbl proto-oncogene	Homo sapiens	123-126	
31120930-5	2019	Phosphorylation of the Cbl protein by by Src resulted in increased E3 activity compared to unphosphorylated cbl or Cbl containing a phosphomimetic Y371E mutation.	Chlorambucil	108-111	Cbl proto-oncogene	Homo sapiens	23-26	
23548104-1	2013	A new polyfluorene derivative containing pendent alkylating chlorambucil (PFP-Cbl) was synthesized and characterized.	Chlorambucil	60-72	Cbl proto-oncogene	Homo sapiens	78-81