PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12679132-7	2003	Argatroban (0.1-0.3 mg/kg/h) significantly accelerated thrombolysis by t-PA in both a dose- and time-dependent fashion.	argatroban	0-10	plasminogen activator, tissue type	Homo sapiens	71-75	
12679132-8	2003	Although argatroban (0.1-0.2 mg/kg/h) did not significantly prolong the aPTT and bleeding time (BT) as compared with control, it significantly accelerated thrombolysis by t-PA at these doses of lower bleeding risk.	argatroban	9-19	plasminogen activator, tissue type	Homo sapiens	171-175	
12679132-9	2003	Argatroban (0.3 mg/kg/h) significantly enhanced thrombolysis by t-PA, while UFH (12.5 anti-XaU/kg/h) attenuated it again, despite equivalent prolongation of the aPTT and BT.	argatroban	0-10	plasminogen activator, tissue type	Homo sapiens	64-68	
12679132-10	2003	We conclude that argatroban seems to be a more efficient and safer anticoagulant than UFH for the prevention of thrombus formation and acceleration of t-PA-induced thrombolysis.	argatroban	17-27	plasminogen activator, tissue type	Homo sapiens	151-155	
28507269-1	2017	BACKGROUND AND PURPOSE: We conducted a randomized exploratory study to assess safety and the probability of a favorable outcome with adjunctive argatroban, a direct thrombin-inhibitor, administered to recombinant tissue-type plasminogen activator (r-tPA)-treated ischemic stroke patients.	argatroban	144-154	plasminogen activator, tissue type	Homo sapiens	213-246	
25610642-6	2014	Argatroban is a direct thrombin inhibitor used as an adjunct to intravenous tPA and showed higher rates of complete recanalisation in the ARTTS study with further studies which are now ongoing.	argatroban	0-10	plasminogen activator, tissue type	Homo sapiens	76-79	
22223235-1	2012	BACKGROUND AND PURPOSE: Argatroban is a direct thrombin inhibitor that safely augments recanalization achieved by tissue-type plasminogen activator (tPA) in animal stroke models.	argatroban	24-34	plasminogen activator, tissue type	Homo sapiens	114-147