PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9361377-10 1997 It is well known that argatroban inhibits not only thrombin cleavage of fibrinogen with a Ki of 19 nM, but also thrombin-mediated platelet activation with a Ki of 40 nM [4]. argatroban 22-32 fibrinogen beta chain Homo sapiens 72-82 30695464-6 2016 Based on spiking experiments with another DTI, argatroban, we previously demon- strated that the discrepancy in resulting quantification of fibrinogen concentrations between two different thrombin concentrations used in the Clauss assay may enable monitoring of DTIs. argatroban 47-57 fibrinogen beta chain Homo sapiens 140-150 22425273-8 2012 However, increased plasma fibrinogen levels caused underestimation of argatroban levels using the indirect activity-based assay, whereas the UPLC-MS/MS method was unaffected. argatroban 70-80 fibrinogen beta chain Homo sapiens 26-36 7933735-5 1994 Fibrinogen was also preserved to some extent by argatroban treatment without evidence of systemic embolization. argatroban 48-58 fibrinogen beta chain Homo sapiens 0-10 28766891-0 2017 Influences of argatroban on five fibrinogen assays. argatroban 14-24 fibrinogen beta chain Homo sapiens 33-43 32391222-5 2020 The patient was transitioned to argatroban and developed an acute drop in the fibrinogen level. argatroban 32-42 fibrinogen beta chain Homo sapiens 78-88 32391222-6 2020 With concern for possible DIC, argatroban was held with a repeat panel six hours later revealing a significantly improved fibrinogen level. argatroban 31-41 fibrinogen beta chain Homo sapiens 122-132 32391222-8 2020 Argatroban may falsely reduce measured fibrinogen levels in vitro, caused by this method. argatroban 0-10 fibrinogen beta chain Homo sapiens 39-49 28766891-9 2017 CONCLUSION: The influences of argatroban on fibrinogen assays differ greatly, clinicians should be aware of the influences of argatroban on the fibrinogen assays used on site to avoid misdiagnoses. argatroban 126-136 fibrinogen beta chain Homo sapiens 144-154