PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9361377-10	1997	It is well known that argatroban inhibits not only thrombin cleavage of fibrinogen with a Ki of 19 nM, but also thrombin-mediated platelet activation with a Ki of 40 nM [4].	argatroban	22-32	fibrinogen beta chain	Homo sapiens	72-82	
30695464-6	2016	Based on spiking experiments with another DTI, argatroban, we previously demon- strated that the discrepancy in resulting quantification of fibrinogen concentrations between two different thrombin concentrations used in the Clauss assay may enable monitoring of DTIs.	argatroban	47-57	fibrinogen beta chain	Homo sapiens	140-150	
22425273-8	2012	However, increased plasma fibrinogen levels caused underestimation of argatroban levels using the indirect activity-based assay, whereas the UPLC-MS/MS method was unaffected.	argatroban	70-80	fibrinogen beta chain	Homo sapiens	26-36	
7933735-5	1994	Fibrinogen was also preserved to some extent by argatroban treatment without evidence of systemic embolization.	argatroban	48-58	fibrinogen beta chain	Homo sapiens	0-10	
28766891-0	2017	Influences of argatroban on five fibrinogen assays.	argatroban	14-24	fibrinogen beta chain	Homo sapiens	33-43	
32391222-5	2020	The patient was transitioned to argatroban and developed an acute drop in the fibrinogen level.	argatroban	32-42	fibrinogen beta chain	Homo sapiens	78-88	
32391222-6	2020	With concern for possible DIC, argatroban was held with a repeat panel six hours later revealing a significantly improved fibrinogen level.	argatroban	31-41	fibrinogen beta chain	Homo sapiens	122-132	
32391222-8	2020	Argatroban may falsely reduce measured fibrinogen levels in vitro, caused by this method.	argatroban	0-10	fibrinogen beta chain	Homo sapiens	39-49	
28766891-9	2017	CONCLUSION: The influences of argatroban on fibrinogen assays differ greatly, clinicians should be aware of the influences of argatroban on the fibrinogen assays used on site to avoid misdiagnoses.	argatroban	126-136	fibrinogen beta chain	Homo sapiens	144-154