PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28963904-5 2017 The synthetic xanthone 11 showed the best inhibitory effect on AChE and a molecular modeling study revealed that 11 targeted both the catalytic active site (CAS) and the peripheral anionic site (PAS) of AChE. cas 157-160 acetylcholinesterase (Cartwright blood group) Homo sapiens 63-67 29775949-8 2018 The Lineweaver-Burk plot and docking study showed that compound 5 h targeted both the catalytic active site (CAS) and the peripheral anionic site (PAS) of AChE. cas 109-112 acetylcholinesterase (Cartwright blood group) Homo sapiens 155-159 28963904-5 2017 The synthetic xanthone 11 showed the best inhibitory effect on AChE and a molecular modeling study revealed that 11 targeted both the catalytic active site (CAS) and the peripheral anionic site (PAS) of AChE. cas 157-160 acetylcholinesterase (Cartwright blood group) Homo sapiens 203-207 27392529-3 2016 AChE molecular modeling studies of these hybrids indicated that tacrine moiety interacts in the bottom of the gorge with the catalytic active site (CAS) while tianeptine binds to peripheral anionic site (PAS). cas 148-151 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-4 27214510-5 2016 Based on the docking study of AChE, the prototype compound 4o was laid across the active site and occupied both peripheral anionic site (PAS) and catalytic anionic site (CAS). cas 170-173 acetylcholinesterase (Cartwright blood group) Homo sapiens 30-34 27766908-6 2017 Molecular docking studies of the most active compound 7 in AChE showed that this compound can interact with both the catalytic active site (CAS) and the peripheral anionic site (PAS) of AChE. cas 140-143 acetylcholinesterase (Cartwright blood group) Homo sapiens 59-63 28646405-6 2017 Such orientation of K203 experiences favorable interaction with the surrounding residues of catalytic anionic site (CAS) and peripheral anionic site (PAS) of tabun-inhibited AChE. cas 116-119 acetylcholinesterase (Cartwright blood group) Homo sapiens 174-178 21211982-3 2011 A Lineweaver-Burk plot and molecular modeling study showed that these hybrids targeted both the catalytic active site (CAS) and the peripheral anionic site (PAS) of AChE. cas 119-122 acetylcholinesterase (Cartwright blood group) Homo sapiens 165-169 24475704-3 2013 A Lineweaver-Burk plot and molecular modeling study showed that these derivatives targeted both the catalytic active site (CAS) and the peripheral anionic site (PAS) of AChE. cas 123-126 acetylcholinesterase (Cartwright blood group) Homo sapiens 169-173