PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17493651-5	2007	These actions of EGCG are mediated via activation of a nPKC, Ras, MEKK1, MEK3, p38delta-ERK1/2 signaling cascade which leads to increased activator protein 1 (AP1) and CAATT enhancer binding protein (C/EBP) transcription factor expression, increased binding of these factors to DNA, and increased gene transcription.	epigallocatechin gallate	17-21	mitogen-activated protein kinase kinase 3	Homo sapiens	73-77	
16404707-5	2006	Mechanistic studies indicate that EGCG alters mitogen-activated protein kinase cascade function to activate involucrin gene transcription via a Ras, MEKK1, MEK3, ERK1/2-p38delta cascade that targets AP1 and CAATT enhancer binding protein transcription factors.	epigallocatechin gallate	34-38	mitogen-activated protein kinase kinase 3	Homo sapiens	156-160	
15044435-3	2004	We have reported previously that (-)-epigallocatechin-3-gallate (EGCG), a green tea polyphenol antioxidant, stimulates expression of the keratinocyte differentiation marker, involucrin (hINV), via a Ras, MEKK1, MEK3, p38delta signaling cascade (Balasubramanian, S., Efimova, T., and Eckert, R. L. (2002) J. Biol.	epigallocatechin gallate	33-63	mitogen-activated protein kinase kinase 3	Homo sapiens	211-215	
15044435-3	2004	We have reported previously that (-)-epigallocatechin-3-gallate (EGCG), a green tea polyphenol antioxidant, stimulates expression of the keratinocyte differentiation marker, involucrin (hINV), via a Ras, MEKK1, MEK3, p38delta signaling cascade (Balasubramanian, S., Efimova, T., and Eckert, R. L. (2002) J. Biol.	epigallocatechin gallate	65-69	mitogen-activated protein kinase kinase 3	Homo sapiens	211-215	
11698415-10	2002	Signal transduction analysis indicates that the EGCG response requires Ras, MEKK1, MEK3, and p38 kinases.	epigallocatechin gallate	48-52	mitogen-activated protein kinase kinase 3	Homo sapiens	83-87