PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33997996-5	2021	In addition, low dose of EGCG also regulated autophagy pathway associated protein (LC3B II and Beclin) expression and this autophagy pathway was blocked by PI3K/AKT inhibitor; moreover, knockdown of ATG5 reversed EGCG-induced apoptosis in 5,637 cells, indicating that EGCG might inhibit the bladder cancer through autophagy pathway.	epigallocatechin gallate	25-29	autophagy related 5	Homo sapiens	199-203	
33997996-5	2021	In addition, low dose of EGCG also regulated autophagy pathway associated protein (LC3B II and Beclin) expression and this autophagy pathway was blocked by PI3K/AKT inhibitor; moreover, knockdown of ATG5 reversed EGCG-induced apoptosis in 5,637 cells, indicating that EGCG might inhibit the bladder cancer through autophagy pathway.	epigallocatechin gallate	213-217	autophagy related 5	Homo sapiens	199-203	
33997996-5	2021	In addition, low dose of EGCG also regulated autophagy pathway associated protein (LC3B II and Beclin) expression and this autophagy pathway was blocked by PI3K/AKT inhibitor; moreover, knockdown of ATG5 reversed EGCG-induced apoptosis in 5,637 cells, indicating that EGCG might inhibit the bladder cancer through autophagy pathway.	epigallocatechin gallate	213-217	autophagy related 5	Homo sapiens	199-203	
33603339-7	2021	Moreover, qRT-PCRrevealed that genes associated with cell apoptosis (caspase-3, 8, 9, Fas) and autophagy (Atg 5, Atg 7, Atg 12) were up-regulated after EGCG treatment.	epigallocatechin gallate	152-156	autophagy related 5	Homo sapiens	106-111	
32309347-10	2020	After exposed to H2O2, EGCG upregulated the levels of Atg5, Atg7, LC3 II/I, and the Atg5-Atg12 complex in HUVECs, while downregulated apoptosis-related protein.	epigallocatechin gallate	23-27	autophagy related 5	Homo sapiens	54-58	
32309347-10	2020	After exposed to H2O2, EGCG upregulated the levels of Atg5, Atg7, LC3 II/I, and the Atg5-Atg12 complex in HUVECs, while downregulated apoptosis-related protein.	epigallocatechin gallate	23-27	autophagy related 5	Homo sapiens	84-88	
30452052-7	2018	In addition, the normal autophagic flux induced by EGCG at both the initiation and formation stages regulated Atg5 and Beclin-1 after SAH for the timely elimination of damaged mitochondria.	epigallocatechin gallate	51-55	autophagy related 5	Homo sapiens	110-114	
27200496-6	2017	EGCG markedly increased the protein levels of Bax, cleaved caspase-9, cleaved caspase-3, Atg5, Atg7, Atg12, Beclin-1, and LC3B-II, as well as significantly decreased the expression of Bcl-2, phosphorylated AKT (Ser473) and phosphorylation of STAT3 on Tyr705 by western blotting in CAR cells.	epigallocatechin gallate	0-4	autophagy related 5	Homo sapiens	89-93	
26742518-6	2017	Subsequently, EGCG can restore the disrupted autophagy flux after SAH both at the initiation and formation stages by regulating Atg5, LC3B, and Becn-1 (Beclin-1) mRNA expressions.	epigallocatechin gallate	14-18	autophagy related 5	Homo sapiens	128-132