PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2894945-1	1988	Competitive inhibition studies using human liver microsomes have shown that quinidine (QD) has an exceptionally high affinity (60 nM) for the genetically variable cytochrome P-450 that catalyzes the formation of 4-hydroxydebrisoquine and dehydrosparteines from debrisoquine and sparteine.	4-hydroxydebrisoquin	212-233	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	163-179	
3741500-2	1986	The metabolism of this drug to its principal metabolite, 4-hydroxydebrisoquine, is catalyzed by a discrete isozyme of cytochrome P-450.	4-hydroxydebrisoquin	57-78	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	118-134