PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21903582-4	2011	High CO(2) levels led to increased levels of microRNA-183 (miR-183), which in turn decreased expression of IDH2 (isocitrate dehydrogenase 2).	co(2)	5-10	isocitrate dehydrogenase (NADP(+)) 2	Homo sapiens	107-111	
21903582-5	2011	The high CO(2)-induced decrease in cell proliferation was rescued by alpha-ketoglutarate and overexpression of IDH2, whereas proliferation decreased in normocapnic cells transfected with siRNA for IDH2.	co(2)	9-14	isocitrate dehydrogenase (NADP(+)) 2	Homo sapiens	111-115	
21903582-5	2011	The high CO(2)-induced decrease in cell proliferation was rescued by alpha-ketoglutarate and overexpression of IDH2, whereas proliferation decreased in normocapnic cells transfected with siRNA for IDH2.	co(2)	9-14	isocitrate dehydrogenase (NADP(+)) 2	Homo sapiens	197-201	
21903582-7	2011	Accordingly, we provide evidence that high CO(2) induces miR-183, which down-regulates IDH2, thus impairing mitochondrial function and cell proliferation.	co(2)	43-48	isocitrate dehydrogenase (NADP(+)) 2	Homo sapiens	87-91