PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25999974-3 2015 Among the known effectors of ABA signaling, the ABI1 (abscisic acid-insensitive 1) protein phosphatase, which belongs to group A of the type 2C protein phosphatases, is recognized as a key component of the pathway. Abscisic Acid 29-32 Protein phosphatase 2C family protein Arabidopsis thaliana 48-52 25999974-3 2015 Among the known effectors of ABA signaling, the ABI1 (abscisic acid-insensitive 1) protein phosphatase, which belongs to group A of the type 2C protein phosphatases, is recognized as a key component of the pathway. Abscisic Acid 29-32 Protein phosphatase 2C family protein Arabidopsis thaliana 54-81 25999974-5 2015 This mini-review discusses recent progress in understanding the role of ABI1 in ABA signaling, with particular emphasis on recent data that link ABI1 to protein degradation via the UPS. Abscisic Acid 80-83 Protein phosphatase 2C family protein Arabidopsis thaliana 72-76 24561249-6 2014 The transcription of a number of ABA signaling components, including ABI1, ERA1, ABI3, and ABF3, was up-regulated in AtWNK9 transgenic plants and down-regulated in the wnk9 mutant in response to ABA. Abscisic Acid 33-36 Protein phosphatase 2C family protein Arabidopsis thaliana 69-73 25266633-8 2014 However, the Arabidopsis clade-A PROTEIN PHOSPHATASE2C mutant abscisic acid-insensitive1 (abi1-1) does not close the stomata when epidermal strips were treated with H2S, suggesting that H2S required a functional ABI1. Abscisic Acid 62-75 Protein phosphatase 2C family protein Arabidopsis thaliana 90-94 25266633-8 2014 However, the Arabidopsis clade-A PROTEIN PHOSPHATASE2C mutant abscisic acid-insensitive1 (abi1-1) does not close the stomata when epidermal strips were treated with H2S, suggesting that H2S required a functional ABI1. Abscisic Acid 62-75 Protein phosphatase 2C family protein Arabidopsis thaliana 212-216 24828206-6 2014 Competitive GST pull-down assay and analysis of phosphatase activity demonstrated that AtMYB44 and ABI1 competed for binding to RCAR1/PYL9 and thereby reduced the inhibitory effect of RCAR1/PYL9 on ABI1 phosphatase activity in the presence of ABA in vitro. Abscisic Acid 243-246 Protein phosphatase 2C family protein Arabidopsis thaliana 99-103 24828206-6 2014 Competitive GST pull-down assay and analysis of phosphatase activity demonstrated that AtMYB44 and ABI1 competed for binding to RCAR1/PYL9 and thereby reduced the inhibitory effect of RCAR1/PYL9 on ABI1 phosphatase activity in the presence of ABA in vitro. Abscisic Acid 243-246 Protein phosphatase 2C family protein Arabidopsis thaliana 198-202 24492258-5 2014 Interestingly, an ABA-insensitive mutant, abi1-1, did not show ABA inhibition of hypocotyl elongation or ABA-induced dephosphorylation of H(+)-ATPase. Abscisic Acid 18-21 Protein phosphatase 2C family protein Arabidopsis thaliana 42-48 24492258-6 2014 This indicates that ABI1, which is an early ABA signaling component through the ABA receptor PYR/PYL/RCARs (pyrabactin resistance/pyrabactin resistance 1-like/regulatory component of ABA receptor), is involved in these responses. Abscisic Acid 44-47 Protein phosphatase 2C family protein Arabidopsis thaliana 20-24 25795738-4 2015 The CNI2 gene encodes ABI1, a phosphatase type 2C protein, which negatively regulates abscisic acid (ABA) signal transduction. Abscisic Acid 86-99 Protein phosphatase 2C family protein Arabidopsis thaliana 22-26 25795738-4 2015 The CNI2 gene encodes ABI1, a phosphatase type 2C protein, which negatively regulates abscisic acid (ABA) signal transduction. Abscisic Acid 101-104 Protein phosphatase 2C family protein Arabidopsis thaliana 22-26 25795738-7 2015 Accordingly, the ABA-insensitive mutant abi1-1, which could not bind to the ABA-ABA receptor complex, was not insensitive and restored normal sensitivity to high C/low N stress. Abscisic Acid 17-20 Protein phosphatase 2C family protein Arabidopsis thaliana 40-46 25795738-10 2015 Taken together, these results suggest direct cross-talk between C/N and non-canonical ABA signalling pathways, regulated by ABI1, in plants. Abscisic Acid 86-89 Protein phosphatase 2C family protein Arabidopsis thaliana 124-128 26786013-5 2015 ABI1 functions as a negative regulator of abscisic acid (ABA) signal transduction. Abscisic Acid 42-55 Protein phosphatase 2C family protein Arabidopsis thaliana 0-4 26786013-5 2015 ABI1 functions as a negative regulator of abscisic acid (ABA) signal transduction. Abscisic Acid 57-60 Protein phosphatase 2C family protein Arabidopsis thaliana 0-4 25038254-2 2014 Of all Arabidopsis thaliana PP2Cs, members of PP2C subfamily A, including ABI1, have been shown to be key negative regulators of abscisic acid (ABA) signalling pathways, which regulate plant growth and development as well as tolerance to adverse environmental conditions. Abscisic Acid 129-142 Protein phosphatase 2C family protein Arabidopsis thaliana 74-78 25038254-2 2014 Of all Arabidopsis thaliana PP2Cs, members of PP2C subfamily A, including ABI1, have been shown to be key negative regulators of abscisic acid (ABA) signalling pathways, which regulate plant growth and development as well as tolerance to adverse environmental conditions. Abscisic Acid 144-147 Protein phosphatase 2C family protein Arabidopsis thaliana 74-78 25038254-9 2014 Furthermore, while overexpression of ABI1 in plants induced an ABA-insensitive phenotype, Arabidopsis plants overexpressing AtPP2CF1 (AtPP2CF1oe) were weakly hypersensitive to ABA during seed germination and drought stress. Abscisic Acid 63-66 Protein phosphatase 2C family protein Arabidopsis thaliana 37-41 24812105-10 2014 Whereas introduction of the abi1-1, abi3-1, or abi4-103 mutation could completely eliminate the ABA hypersensitivity of cer9, introduction of abi5 resulted only in partial suppression. Abscisic Acid 96-99 Protein phosphatase 2C family protein Arabidopsis thaliana 28-34 24637173-3 2014 Here, we show that the Arabidopsis thaliana protein phosphatase type 2C, ABI1, a negative regulator of abscisic acid signaling, is involved in the regulation of ethylene biosynthesis under oxidative stress conditions. Abscisic Acid 103-116 Protein phosphatase 2C family protein Arabidopsis thaliana 73-77 24637173-9 2014 The ABI1 contribution to stress phenotype underpins its role in the interplay between the abscisic acid (ABA) and ethylene signaling pathways. Abscisic Acid 90-103 Protein phosphatase 2C family protein Arabidopsis thaliana 4-8 24637173-9 2014 The ABI1 contribution to stress phenotype underpins its role in the interplay between the abscisic acid (ABA) and ethylene signaling pathways. Abscisic Acid 105-108 Protein phosphatase 2C family protein Arabidopsis thaliana 4-8 24561249-6 2014 The transcription of a number of ABA signaling components, including ABI1, ERA1, ABI3, and ABF3, was up-regulated in AtWNK9 transgenic plants and down-regulated in the wnk9 mutant in response to ABA. Abscisic Acid 195-198 Protein phosphatase 2C family protein Arabidopsis thaliana 69-73 23934343-11 2013 We also show that GmPYL1 interacts with AtABI1 in an ABA-dependent manner in plant cells. Abscisic Acid 53-56 Protein phosphatase 2C family protein Arabidopsis thaliana 40-46 24081610-8 2013 Moreover, early ABA-responsive genes, ABI1, ABI5, NCED3, SNF4 and AREB2, were rapidly induced in AtHSP17.8-overexpressing transgenic Arabidopsis and lettuce. Abscisic Acid 16-19 Protein phosphatase 2C family protein Arabidopsis thaliana 38-42 23934343-12 2013 Three GmPYLs differentially inhibit AtABI1 and GmPP2C1 in an ABA-dependent or -enhanced manner in vitro. Abscisic Acid 61-64 Protein phosphatase 2C family protein Arabidopsis thaliana 36-42 23630285-5 2013 Among those, we detected the central ABA signaling phosphatase ABI1 (abscisic-acid insensitive 1) and the calcium-dependent protein kinase 21 (CPK21). Abscisic Acid 37-40 Protein phosphatase 2C family protein Arabidopsis thaliana 63-67 24383079-7 2013 The ABA-related genes ABA1, ABA2 ABI1 and ABI5 were all up-regulated in the TaWRKY79 transgenic plants, suggesting that the transcription factor operates in an ABA-dependent pathway. Abscisic Acid 4-7 Protein phosphatase 2C family protein Arabidopsis thaliana 33-37 24383079-7 2013 The ABA-related genes ABA1, ABA2 ABI1 and ABI5 were all up-regulated in the TaWRKY79 transgenic plants, suggesting that the transcription factor operates in an ABA-dependent pathway. Abscisic Acid 22-25 Protein phosphatase 2C family protein Arabidopsis thaliana 33-37 23658427-8 2013 CIPK26 was found to interact with the ABA signalling components ABI1, ABI2, and ABI5. Abscisic Acid 38-41 Protein phosphatase 2C family protein Arabidopsis thaliana 64-68 23660402-3 2013 Following NaCl treatment, the expressions of ABI1, ABI2 and AtPP2CA, which encode type 2C serine/threonine protein phosphatases (PP2Cs) that act as negative regulators in abscisic acid (ABA) signaling, were suppressed in AtMYB20-OX but induced in AtMYB20-SRDX. Abscisic Acid 171-184 Protein phosphatase 2C family protein Arabidopsis thaliana 45-49 23660402-3 2013 Following NaCl treatment, the expressions of ABI1, ABI2 and AtPP2CA, which encode type 2C serine/threonine protein phosphatases (PP2Cs) that act as negative regulators in abscisic acid (ABA) signaling, were suppressed in AtMYB20-OX but induced in AtMYB20-SRDX. Abscisic Acid 186-189 Protein phosphatase 2C family protein Arabidopsis thaliana 45-49 23630285-5 2013 Among those, we detected the central ABA signaling phosphatase ABI1 (abscisic-acid insensitive 1) and the calcium-dependent protein kinase 21 (CPK21). Abscisic Acid 37-40 Protein phosphatase 2C family protein Arabidopsis thaliana 69-96 23630285-11 2013 Interestingly, the ABA-induced SLAH3/CPK21 interaction was modulated by ABI1 and the ABA receptor RCAR1/PYL9 [regulatory components of ABA receptor 1/PYR1 (pyrabactin resistance 1)-like protein 9]. Abscisic Acid 19-22 Protein phosphatase 2C family protein Arabidopsis thaliana 72-76 23630285-12 2013 We therefore propose that ABA signaling via inhibition of ABI1 modulates the apparent association of a signaling and transport complex within membrane domains that is necessary for phosphorylation and activation of the S-type anion channel SLAH3 by CPK21. Abscisic Acid 26-29 Protein phosphatase 2C family protein Arabidopsis thaliana 58-62 23606412-6 2013 Moreover, microarray and qRT-PCR assays showed that GsWRKY20 mediated ABA signalling by promoting the expression of negative regulators of ABA signalling, such as AtWRKY40, ABI1, and ABI2, while repressing the expression of the positive regulators of ABA, for example ABI5, ABI4, and ABF4. Abscisic Acid 70-73 Protein phosphatase 2C family protein Arabidopsis thaliana 173-177 23606412-6 2013 Moreover, microarray and qRT-PCR assays showed that GsWRKY20 mediated ABA signalling by promoting the expression of negative regulators of ABA signalling, such as AtWRKY40, ABI1, and ABI2, while repressing the expression of the positive regulators of ABA, for example ABI5, ABI4, and ABF4. Abscisic Acid 139-142 Protein phosphatase 2C family protein Arabidopsis thaliana 173-177 23606412-6 2013 Moreover, microarray and qRT-PCR assays showed that GsWRKY20 mediated ABA signalling by promoting the expression of negative regulators of ABA signalling, such as AtWRKY40, ABI1, and ABI2, while repressing the expression of the positive regulators of ABA, for example ABI5, ABI4, and ABF4. Abscisic Acid 139-142 Protein phosphatase 2C family protein Arabidopsis thaliana 173-177 23483290-9 2013 Moreover, the transcript levels of ABA biosynthesis (ABA1, ABA2), ABA signaling (ABI1, ABI2) and stress-responsive genes, including RD29A and CBF3, were generally higher in GmNFYA3 plants than in wild-type controls under normal conditions. Abscisic Acid 53-56 Protein phosphatase 2C family protein Arabidopsis thaliana 81-85 23483290-9 2013 Moreover, the transcript levels of ABA biosynthesis (ABA1, ABA2), ABA signaling (ABI1, ABI2) and stress-responsive genes, including RD29A and CBF3, were generally higher in GmNFYA3 plants than in wild-type controls under normal conditions. Abscisic Acid 35-38 Protein phosphatase 2C family protein Arabidopsis thaliana 81-85 23404898-7 2013 Taken together, the data provide new evidence for an important role for ABA in regulating strawberry fruit ripening in the processes of which the type 2C protein phosphatase ABI1 serves as a negative regulator. Abscisic Acid 72-75 Protein phosphatase 2C family protein Arabidopsis thaliana 174-178 22661072-10 2012 ABA inhibits seed germination and seedling growth and phenotype analysis showed that the integration of abi1-1 mutation into the RAP2.6L overexpression lines reduces ABA sensitivity. Abscisic Acid 0-3 Protein phosphatase 2C family protein Arabidopsis thaliana 104-110 23437216-4 2013 ABA can enhance the interaction between AaPYL9 and AtABI1 while AaPYL9-89 Pro Ser and AaPYL9-116 His Ala point mutations abolishes the interaction. Abscisic Acid 0-3 Protein phosphatase 2C family protein Arabidopsis thaliana 51-57 22661072-10 2012 ABA inhibits seed germination and seedling growth and phenotype analysis showed that the integration of abi1-1 mutation into the RAP2.6L overexpression lines reduces ABA sensitivity. Abscisic Acid 166-169 Protein phosphatase 2C family protein Arabidopsis thaliana 104-110 22661072-11 2012 These suggest that RAP2.6L overexpression delays waterlogging induced premature senescence and might function through ABI1-mediated ABA signaling pathway. Abscisic Acid 132-135 Protein phosphatase 2C family protein Arabidopsis thaliana 118-122 22251383-0 2012 ROP11 GTPase negatively regulates ABA signaling by protecting ABI1 phosphatase activity from inhibition by the ABA receptor RCAR1/PYL9 in Arabidopsis. Abscisic Acid 34-37 Protein phosphatase 2C family protein Arabidopsis thaliana 62-66 22730405-7 2012 Our study identifies a critical component in ABA and H2O2 signaling that is involved in stomatal movement and resolves a long-standing mystery about the differential functions of ABI1 and ABI2 in this process. Abscisic Acid 45-48 Protein phosphatase 2C family protein Arabidopsis thaliana 179-183 22251383-8 2012 Finally, we provided biochemical evidence that CA-ROP11 protects ABI1 phosphatase activity from inhibition by RCAR1/PYL9 and thus negatively regulates ABA signaling in plant cells. Abscisic Acid 151-154 Protein phosphatase 2C family protein Arabidopsis thaliana 65-69 21853252-8 2012 Analyses of the abscisic acid mutants, aba1-1 and abi1-1, indicate that carnitine and proline may act through a modulation of the ABA pathway. Abscisic Acid 130-133 Protein phosphatase 2C family protein Arabidopsis thaliana 50-56 22090030-0 2012 Molecular mechanism for inhibition of a critical component in the Arabidopsis thaliana abscisic acid signal transduction pathways, SnRK2.6, by protein phosphatase ABI1. Abscisic Acid 87-100 Protein phosphatase 2C family protein Arabidopsis thaliana 163-167 21885535-1 2011 It is known that the clade A protein phosphatase 2Cs (PP2Cs), including ABI1 and ABI2 and other PP2C members, are key players that function directly downstream of the PYR/PYL/RCAR abscisic acid (ABA) receptors. Abscisic Acid 180-193 Protein phosphatase 2C family protein Arabidopsis thaliana 72-76 21885535-1 2011 It is known that the clade A protein phosphatase 2Cs (PP2Cs), including ABI1 and ABI2 and other PP2C members, are key players that function directly downstream of the PYR/PYL/RCAR abscisic acid (ABA) receptors. Abscisic Acid 195-198 Protein phosphatase 2C family protein Arabidopsis thaliana 72-76 21556325-4 2011 Genetic analysis demonstrated that CPR5 gene may be located downstream of the ABI1 in the ABA signaling pathway. Abscisic Acid 90-93 Protein phosphatase 2C family protein Arabidopsis thaliana 78-82 21821598-7 2011 In this study, transcriptome analysis reveals that the M6PR transgene activated the downstream abscisic acid (ABA) pathway by up-regulation of ABA receptor genes (PYL4, PYL5, and PYL6) and down-regulation of protein phosphatase 2C genes (ABI1 and ABI2). Abscisic Acid 95-108 Protein phosphatase 2C family protein Arabidopsis thaliana 238-242 21821598-7 2011 In this study, transcriptome analysis reveals that the M6PR transgene activated the downstream abscisic acid (ABA) pathway by up-regulation of ABA receptor genes (PYL4, PYL5, and PYL6) and down-regulation of protein phosphatase 2C genes (ABI1 and ABI2). Abscisic Acid 110-113 Protein phosphatase 2C family protein Arabidopsis thaliana 238-242 21525137-8 2011 Expression levels of abscisic acid-related genes ABI1, ABI2, RAB18, PP2CA, and SOT12 were substantially reduced in salt-treated npc4 plants. Abscisic Acid 21-34 Protein phosphatase 2C family protein Arabidopsis thaliana 49-53 21371039-0 2011 cGMP-dependent ABA-induced stomatal closure in the ABA-insensitive Arabidopsis mutant abi1-1. Abscisic Acid 15-18 Protein phosphatase 2C family protein Arabidopsis thaliana 86-92 21371039-0 2011 cGMP-dependent ABA-induced stomatal closure in the ABA-insensitive Arabidopsis mutant abi1-1. Abscisic Acid 51-54 Protein phosphatase 2C family protein Arabidopsis thaliana 86-92 21371039-3 2011 We have examined the signalling events during cGMP-dependent ABA-induced stomatal closure in wild-type Arabidopsis plants and plants of the ABA-insensitive Arabidopsis mutant abi1-1. Abscisic Acid 61-64 Protein phosphatase 2C family protein Arabidopsis thaliana 175-181 20490504-6 2010 Further analysis indicated that transgenic plants showed increased transcription of the stress-related genes, RD29A, RD29B, RAB18 and RD22, and the ABA-related genes, ABI1 and NCED3 under dehydration conditions. Abscisic Acid 148-151 Protein phosphatase 2C family protein Arabidopsis thaliana 167-171 20488890-9 2010 In addition, the response of ABA-inducible genes such as ABI1, ABI2, RD29A, and Erd10 was reduced in the mutant plants. Abscisic Acid 29-32 Protein phosphatase 2C family protein Arabidopsis thaliana 57-61 19705149-0 2009 Gene expression profiling of ozone-treated Arabidopsis abi1td insertional mutant: protein phosphatase 2C ABI1 modulates biosynthesis ratio of ABA and ethylene. Abscisic Acid 142-145 Protein phosphatase 2C family protein Arabidopsis thaliana 55-59 19769575-7 2010 RCAR3 was identified in a screen for interactors of the PP2Cs ABI1 and ABI2, which are key regulators of ABA responses. Abscisic Acid 105-108 Protein phosphatase 2C family protein Arabidopsis thaliana 62-66 19769575-10 2010 In addition, regulation of the protein phosphatase activity by RCAR1 and RCAR3 was more sensitive to ABA for ABI1 than for ABI2. Abscisic Acid 101-104 Protein phosphatase 2C family protein Arabidopsis thaliana 109-113 19837818-0 2009 Expression of the Arabidopsis mutant ABI1 gene alters abscisic acid sensitivity, stomatal development, and growth morphology in gray poplars. Abscisic Acid 54-67 Protein phosphatase 2C family protein Arabidopsis thaliana 37-41 19837818-3 2009 development were examined by ectopic expression of the Arabidopsis (Arabidopsis thaliana) mutant abi1 (for abscisic acid insensitive1) gene. Abscisic Acid 107-120 Protein phosphatase 2C family protein Arabidopsis thaliana 97-101 19837818-4 2009 The expression resulted in an ABA-insensitive phenotype revealed by a strong tendency of abi1 poplars to wilt, impaired responsiveness of their stomata to ABA, and an ABA-resistant bud outgrowth. Abscisic Acid 30-33 Protein phosphatase 2C family protein Arabidopsis thaliana 89-93 19855047-6 2009 Furthermore, HAB1 and the related PP2Cs ABI1 and ABI2 interact with OST1 in vivo, and mutations in the corresponding genes strongly affect OST1 activation by ABA. Abscisic Acid 158-161 Protein phosphatase 2C family protein Arabidopsis thaliana 40-44 19874541-2 2010 The group-A PP2Cs, of which ABI1 is the prototypical member, are protein phosphatases that play critical roles as negative regulators very early in ABA signal transduction. Abscisic Acid 148-151 Protein phosphatase 2C family protein Arabidopsis thaliana 28-32 19874541-7 2010 Interestingly, the most robust in planta ABI1-interacting proteins in all LC-MS/MS experiments were nine of the 14 PYR/PYL/RCAR proteins, which were recently reported as ABA-binding signal transduction proteins, providing evidence for in vivo PYR/PYL/RCAR interactions with ABI1 in Arabidopsis. Abscisic Acid 170-173 Protein phosphatase 2C family protein Arabidopsis thaliana 41-45 19874541-7 2010 Interestingly, the most robust in planta ABI1-interacting proteins in all LC-MS/MS experiments were nine of the 14 PYR/PYL/RCAR proteins, which were recently reported as ABA-binding signal transduction proteins, providing evidence for in vivo PYR/PYL/RCAR interactions with ABI1 in Arabidopsis. Abscisic Acid 170-173 Protein phosphatase 2C family protein Arabidopsis thaliana 274-278 19874541-8 2010 ABI1-PYR1 interaction was stimulated within 5 min of ABA treatment in Arabidopsis. Abscisic Acid 53-56 Protein phosphatase 2C family protein Arabidopsis thaliana 0-4 19874541-11 2010 These findings demonstrate that ABI1 can interact with several PYR/PYL/RCAR family members in Arabidopsis, that PYR1-ABI1 interaction is rapidly stimulated by ABA in Arabidopsis and indicate new SnRK2 kinase-PYR/PYL/RCAR interactions in an emerging model for PYR/PYL/RCAR-mediated ABA signalling. Abscisic Acid 159-162 Protein phosphatase 2C family protein Arabidopsis thaliana 32-36 19874541-11 2010 These findings demonstrate that ABI1 can interact with several PYR/PYL/RCAR family members in Arabidopsis, that PYR1-ABI1 interaction is rapidly stimulated by ABA in Arabidopsis and indicate new SnRK2 kinase-PYR/PYL/RCAR interactions in an emerging model for PYR/PYL/RCAR-mediated ABA signalling. Abscisic Acid 159-162 Protein phosphatase 2C family protein Arabidopsis thaliana 117-121 19874541-11 2010 These findings demonstrate that ABI1 can interact with several PYR/PYL/RCAR family members in Arabidopsis, that PYR1-ABI1 interaction is rapidly stimulated by ABA in Arabidopsis and indicate new SnRK2 kinase-PYR/PYL/RCAR interactions in an emerging model for PYR/PYL/RCAR-mediated ABA signalling. Abscisic Acid 281-284 Protein phosphatase 2C family protein Arabidopsis thaliana 32-36 19874541-11 2010 These findings demonstrate that ABI1 can interact with several PYR/PYL/RCAR family members in Arabidopsis, that PYR1-ABI1 interaction is rapidly stimulated by ABA in Arabidopsis and indicate new SnRK2 kinase-PYR/PYL/RCAR interactions in an emerging model for PYR/PYL/RCAR-mediated ABA signalling. Abscisic Acid 281-284 Protein phosphatase 2C family protein Arabidopsis thaliana 117-121 19837818-10 2009 In shoots, we observed an interaction of ABA with ethylene: abi1 poplars exhibited elevated ethylene production, and the ethylene perception inhibitor Ag(+) antagonized the enhanced shoot growth. Abscisic Acid 41-44 Protein phosphatase 2C family protein Arabidopsis thaliana 60-64 19624469-8 2009 PYL5 and other members of its protein family inhibited HAB1, ABI1 and ABI2 phosphatase activity in an ABA-dependent manner. Abscisic Acid 102-105 Protein phosphatase 2C family protein Arabidopsis thaliana 61-65 19705149-5 2009 Comparisons with available transcriptome data sets revealed the extent of ABI1 involvement in both ABA-dependent and ABA-independent gene expression. Abscisic Acid 99-102 Protein phosphatase 2C family protein Arabidopsis thaliana 74-78 19705149-5 2009 Comparisons with available transcriptome data sets revealed the extent of ABI1 involvement in both ABA-dependent and ABA-independent gene expression. Abscisic Acid 117-120 Protein phosphatase 2C family protein Arabidopsis thaliana 74-78 19705149-6 2009 Furthermore, in O(3) stress the ABA hypersensitivity of abi1td resulted in a significant reduction of the ABA level, ethylene (ET) over-production and O(3) tolerance. Abscisic Acid 32-35 Protein phosphatase 2C family protein Arabidopsis thaliana 56-60 19705149-6 2009 Furthermore, in O(3) stress the ABA hypersensitivity of abi1td resulted in a significant reduction of the ABA level, ethylene (ET) over-production and O(3) tolerance. Abscisic Acid 106-109 Protein phosphatase 2C family protein Arabidopsis thaliana 56-60 19705149-8 2009 We provide a model explaining how ABI1 can regulate both ABA and ET biosynthesis. Abscisic Acid 57-60 Protein phosphatase 2C family protein Arabidopsis thaliana 34-38 19705149-9 2009 Altogether, our findings indicate that ABI1 plays the role of a general signal transducer linking ABA and ET biosynthesis as well as signalling pathways to O(3) stress tolerance. Abscisic Acid 98-101 Protein phosphatase 2C family protein Arabidopsis thaliana 39-43 19705149-0 2009 Gene expression profiling of ozone-treated Arabidopsis abi1td insertional mutant: protein phosphatase 2C ABI1 modulates biosynthesis ratio of ABA and ethylene. Abscisic Acid 142-145 Protein phosphatase 2C family protein Arabidopsis thaliana 105-109 19705149-2 2009 To identify the stress-related signalling pathways and possible cross-talk controlled by an ABA-negative regulator, the protein phosphatase 2C abscisic acid insensitive1 (ABI1), we performed a genome-wide transcription profiling of O(3)-treated wild-type and ABI1 knockout (abi1td) plants. Abscisic Acid 92-95 Protein phosphatase 2C family protein Arabidopsis thaliana 171-175 19705149-2 2009 To identify the stress-related signalling pathways and possible cross-talk controlled by an ABA-negative regulator, the protein phosphatase 2C abscisic acid insensitive1 (ABI1), we performed a genome-wide transcription profiling of O(3)-treated wild-type and ABI1 knockout (abi1td) plants. Abscisic Acid 143-156 Protein phosphatase 2C family protein Arabidopsis thaliana 171-175 19266168-0 2009 Functional analyses of the ABI1-related protein phosphatase type 2C reveal evolutionarily conserved regulation of abscisic acid signaling between Arabidopsis and the moss Physcomitrella patens. Abscisic Acid 114-127 Protein phosphatase 2C family protein Arabidopsis thaliana 27-31 19847119-3 2009 We have shown that the basal land plant Physcomitrella patens and the model plant Arabidopsis thaliana share a conserved abscisic acid (ABA) signaling pathway mediated through ABI1-related type 2C protein phosphatases (PP2Cs). Abscisic Acid 121-134 Protein phosphatase 2C family protein Arabidopsis thaliana 176-180 19847119-3 2009 We have shown that the basal land plant Physcomitrella patens and the model plant Arabidopsis thaliana share a conserved abscisic acid (ABA) signaling pathway mediated through ABI1-related type 2C protein phosphatases (PP2Cs). Abscisic Acid 136-139 Protein phosphatase 2C family protein Arabidopsis thaliana 176-180 19847119-4 2009 Ectopic expression of Arabidopsis abi1-1, a dominant allele of ABI1 that functions as a negative regulator of ABA signaling, or targeted disruption of Physcomitrella ABI1-related gene (PpABI1A) resulted in altered ABA sensitivity and abiotic stress tolerance of Physcomitrella, as demonstrated by osmostress and freezing stress. Abscisic Acid 214-217 Protein phosphatase 2C family protein Arabidopsis thaliana 34-38 19847119-4 2009 Ectopic expression of Arabidopsis abi1-1, a dominant allele of ABI1 that functions as a negative regulator of ABA signaling, or targeted disruption of Physcomitrella ABI1-related gene (PpABI1A) resulted in altered ABA sensitivity and abiotic stress tolerance of Physcomitrella, as demonstrated by osmostress and freezing stress. Abscisic Acid 214-217 Protein phosphatase 2C family protein Arabidopsis thaliana 166-170 19309463-8 2009 We show that application of ABA to Arabidopsis is sufficient to trigger leaf senescence, and that this response is abolished in the ABA-insensitive mutants abi1-1 and abi2-1, but enhanced in the ABA-hypersensitive mutant era1-3. Abscisic Acid 28-31 Protein phosphatase 2C family protein Arabidopsis thaliana 156-162 19309463-8 2009 We show that application of ABA to Arabidopsis is sufficient to trigger leaf senescence, and that this response is abolished in the ABA-insensitive mutants abi1-1 and abi2-1, but enhanced in the ABA-hypersensitive mutant era1-3. Abscisic Acid 132-135 Protein phosphatase 2C family protein Arabidopsis thaliana 156-162 19309463-8 2009 We show that application of ABA to Arabidopsis is sufficient to trigger leaf senescence, and that this response is abolished in the ABA-insensitive mutants abi1-1 and abi2-1, but enhanced in the ABA-hypersensitive mutant era1-3. Abscisic Acid 132-135 Protein phosphatase 2C family protein Arabidopsis thaliana 156-162 19266168-2 2009 Ectopic expression of Arabidopsis (Arabidopsis thaliana) abi1-1, a dominant mutant allele of ABI1 encoding a PP2C involved in the negative regulation of ABA signaling, caused ABA insensitivity of P. patens both in gene expression of late embryogenesis abundant (LEA) genes and in ABA-induced protonemal growth inhibition. Abscisic Acid 153-156 Protein phosphatase 2C family protein Arabidopsis thaliana 57-61 19266168-2 2009 Ectopic expression of Arabidopsis (Arabidopsis thaliana) abi1-1, a dominant mutant allele of ABI1 encoding a PP2C involved in the negative regulation of ABA signaling, caused ABA insensitivity of P. patens both in gene expression of late embryogenesis abundant (LEA) genes and in ABA-induced protonemal growth inhibition. Abscisic Acid 153-156 Protein phosphatase 2C family protein Arabidopsis thaliana 93-97 19266168-2 2009 Ectopic expression of Arabidopsis (Arabidopsis thaliana) abi1-1, a dominant mutant allele of ABI1 encoding a PP2C involved in the negative regulation of ABA signaling, caused ABA insensitivity of P. patens both in gene expression of late embryogenesis abundant (LEA) genes and in ABA-induced protonemal growth inhibition. Abscisic Acid 175-178 Protein phosphatase 2C family protein Arabidopsis thaliana 57-61 19266168-2 2009 Ectopic expression of Arabidopsis (Arabidopsis thaliana) abi1-1, a dominant mutant allele of ABI1 encoding a PP2C involved in the negative regulation of ABA signaling, caused ABA insensitivity of P. patens both in gene expression of late embryogenesis abundant (LEA) genes and in ABA-induced protonemal growth inhibition. Abscisic Acid 175-178 Protein phosphatase 2C family protein Arabidopsis thaliana 57-61 19266168-3 2009 The transgenic abi1-1 plants showed decreased ABA-induced freezing tolerance, and decreased tolerance to osmotic stress. Abscisic Acid 46-49 Protein phosphatase 2C family protein Arabidopsis thaliana 15-19 19407143-2 2009 Key players in ABA signal transduction include the type 2C protein phosphatases (PP2Cs) ABI1 and ABI2, which act by negatively regulating ABA responses. Abscisic Acid 15-18 Protein phosphatase 2C family protein Arabidopsis thaliana 88-92 19407143-2 2009 Key players in ABA signal transduction include the type 2C protein phosphatases (PP2Cs) ABI1 and ABI2, which act by negatively regulating ABA responses. Abscisic Acid 138-141 Protein phosphatase 2C family protein Arabidopsis thaliana 88-92 19407143-5 2009 RCAR1 was shown to bind ABA, to mediate ABA-dependent inactivation of ABI1 or ABI2 in vitro, and to antagonize PP2C action in planta. Abscisic Acid 40-43 Protein phosphatase 2C family protein Arabidopsis thaliana 70-74 19407143-6 2009 Other RCARs also mediated ABA-dependent regulation of ABI1 and ABI2, consistent with a combinatorial assembly of receptor complexes. Abscisic Acid 26-29 Protein phosphatase 2C family protein Arabidopsis thaliana 54-58 18047473-8 2008 BABA-enhanced thermotolerance was partially compromised in the ABA-insensitive mutant, abi1-1, but was augmented in abi2-1. Abscisic Acid 1-4 Protein phosphatase 2C family protein Arabidopsis thaliana 87-93 18835996-8 2008 Double-mutant analyses of dor with ABA-insensitive mutant abi1-1 showed that abi1-1 is epistatic to dor, but no apparent change of phospholipase Dalpha1 was detected between the wild type and dor. Abscisic Acid 35-38 Protein phosphatase 2C family protein Arabidopsis thaliana 77-83 18047473-11 2008 Unexpectedly, abi1-1 and abi2-1 root growth was inhibited more strongly by combined ABA and BABA treatments than by BABA alone. Abscisic Acid 84-87 Protein phosphatase 2C family protein Arabidopsis thaliana 14-20 17158582-4 2007 Mutations in ABI1 or ABI3 induced a strong ethylene-regulated hyponastic growth in the less responsive accession Ler, while the response was abolished in the ABA-hypersensitive era1 in Col-0. Abscisic Acid 158-161 Protein phosphatase 2C family protein Arabidopsis thaliana 13-17 17304219-5 2007 Strongly induced were NCED3, encoding a key enzyme of ABA biosynthesis, and the abscisic acid insensitive 1 (ABI1) clade of genes encoding protein phosphatases type 2C (PP2Cs) involved in the regulation of ABA signalling. Abscisic Acid 80-93 Protein phosphatase 2C family protein Arabidopsis thaliana 109-113 17304219-5 2007 Strongly induced were NCED3, encoding a key enzyme of ABA biosynthesis, and the abscisic acid insensitive 1 (ABI1) clade of genes encoding protein phosphatases type 2C (PP2Cs) involved in the regulation of ABA signalling. Abscisic Acid 206-209 Protein phosphatase 2C family protein Arabidopsis thaliana 109-113 16798945-0 2006 Enhancement of abscisic acid sensitivity and reduction of water consumption in Arabidopsis by combined inactivation of the protein phosphatases type 2C ABI1 and HAB1. Abscisic Acid 15-28 Protein phosphatase 2C family protein Arabidopsis thaliana 152-156 16798945-3 2006 In this work we have generated ABA-hypersensitive drought-avoidant mutants by simultaneous inactivation of two negative regulators of ABA signaling, i.e. the protein phosphatases type 2C (PP2Cs) ABA-INSENSITIVE1 (ABI1) and HYPERSENSITIVE TO ABA1 (HAB1). Abscisic Acid 31-34 Protein phosphatase 2C family protein Arabidopsis thaliana 195-211 16798945-3 2006 In this work we have generated ABA-hypersensitive drought-avoidant mutants by simultaneous inactivation of two negative regulators of ABA signaling, i.e. the protein phosphatases type 2C (PP2Cs) ABA-INSENSITIVE1 (ABI1) and HYPERSENSITIVE TO ABA1 (HAB1). Abscisic Acid 31-34 Protein phosphatase 2C family protein Arabidopsis thaliana 213-217 16798945-3 2006 In this work we have generated ABA-hypersensitive drought-avoidant mutants by simultaneous inactivation of two negative regulators of ABA signaling, i.e. the protein phosphatases type 2C (PP2Cs) ABA-INSENSITIVE1 (ABI1) and HYPERSENSITIVE TO ABA1 (HAB1). Abscisic Acid 134-137 Protein phosphatase 2C family protein Arabidopsis thaliana 195-211 16798945-3 2006 In this work we have generated ABA-hypersensitive drought-avoidant mutants by simultaneous inactivation of two negative regulators of ABA signaling, i.e. the protein phosphatases type 2C (PP2Cs) ABA-INSENSITIVE1 (ABI1) and HYPERSENSITIVE TO ABA1 (HAB1). Abscisic Acid 134-137 Protein phosphatase 2C family protein Arabidopsis thaliana 213-217 16798945-6 2006 In contrast, generation of double hab1-1 abi1-2 and hab1-1 abi1-3 mutants strongly increased plant responsiveness to ABA. Abscisic Acid 117-120 Protein phosphatase 2C family protein Arabidopsis thaliana 41-45 16798945-6 2006 In contrast, generation of double hab1-1 abi1-2 and hab1-1 abi1-3 mutants strongly increased plant responsiveness to ABA. Abscisic Acid 117-120 Protein phosphatase 2C family protein Arabidopsis thaliana 59-63 16798945-7 2006 Thus, both hab1-1 abi1-2 and hab1-1 abi1-3 were particularly sensitive to ABA-mediated inhibition of seed germination. Abscisic Acid 74-77 Protein phosphatase 2C family protein Arabidopsis thaliana 18-22 16798945-7 2006 Thus, both hab1-1 abi1-2 and hab1-1 abi1-3 were particularly sensitive to ABA-mediated inhibition of seed germination. Abscisic Acid 74-77 Protein phosphatase 2C family protein Arabidopsis thaliana 36-40 16798945-10 2006 Taken together, these results reveal cooperative negative regulation of ABA signaling by ABI1 and HAB1 and suggest that fine tuning of ABA signaling can be attained through combined action of PP2Cs. Abscisic Acid 72-75 Protein phosphatase 2C family protein Arabidopsis thaliana 89-93 16798945-10 2006 Taken together, these results reveal cooperative negative regulation of ABA signaling by ABI1 and HAB1 and suggest that fine tuning of ABA signaling can be attained through combined action of PP2Cs. Abscisic Acid 135-138 Protein phosphatase 2C family protein Arabidopsis thaliana 89-93 16365038-0 2006 The regulatory domain of SRK2E/OST1/SnRK2.6 interacts with ABI1 and integrates abscisic acid (ABA) and osmotic stress signals controlling stomatal closure in Arabidopsis. Abscisic Acid 79-92 Protein phosphatase 2C family protein Arabidopsis thaliana 59-63 17080964-4 2006 The repression of 14-3-3 gene expression by GABA is dependent on functional ethylene and ABA signalling pathways, because the response is lost in the etr1-1, abi1-1 and abi2-1 mutants. Abscisic Acid 45-48 Protein phosphatase 2C family protein Arabidopsis thaliana 150-164 16571665-4 2006 ABA induces fibrillin accumulation, and the ABA response regulators ABI1 and ABI2 regulate fibrillin expression. Abscisic Acid 44-47 Protein phosphatase 2C family protein Arabidopsis thaliana 68-72 16571665-5 2006 The abundance of fibrillin transcripts was specifically reduced in the ABA-insensitive abi1 mutant but not in the abi2 mutant. Abscisic Acid 71-74 Protein phosphatase 2C family protein Arabidopsis thaliana 87-91 16571665-9 2006 Thus, ABI1 and ABI2 seem to control fibrillin expression that is involved in mediating ABA-induced photoprotection. Abscisic Acid 87-90 Protein phosphatase 2C family protein Arabidopsis thaliana 6-10 16614222-4 2006 PLDalpha1-produced phosphatidic acid (PA) binds to the ABI1 PP2C to signal ABA-promoted stomatal closure, whereas PLDalpha1 and PA interact with the Galpha subunit of heterotrimeric G protein to mediate ABA inhibition of stomatal opening. Abscisic Acid 75-78 Protein phosphatase 2C family protein Arabidopsis thaliana 55-59 16365038-0 2006 The regulatory domain of SRK2E/OST1/SnRK2.6 interacts with ABI1 and integrates abscisic acid (ABA) and osmotic stress signals controlling stomatal closure in Arabidopsis. Abscisic Acid 94-97 Protein phosphatase 2C family protein Arabidopsis thaliana 59-63 16365038-1 2006 ABI1 and ABI2 encode PP2C-type protein phosphatases and are thought to negatively regulate many aspects of abscisic acid (ABA) signaling, including stomatal closure in Arabidopsis. Abscisic Acid 107-120 Protein phosphatase 2C family protein Arabidopsis thaliana 0-4 16365038-1 2006 ABI1 and ABI2 encode PP2C-type protein phosphatases and are thought to negatively regulate many aspects of abscisic acid (ABA) signaling, including stomatal closure in Arabidopsis. Abscisic Acid 122-125 Protein phosphatase 2C family protein Arabidopsis thaliana 0-4 16365038-5 2006 In the present study, we demonstrated that the abi1-1 mutation, but not the abi2-1 mutation, strongly inhibited ABA-dependent SRK2E/OST1 activation. Abscisic Acid 112-115 Protein phosphatase 2C family protein Arabidopsis thaliana 47-51 16339784-8 2006 Of the other abi mutants, only abi1 had reduced Pro accumulation in response to low water potential and ABA application. Abscisic Acid 104-107 Protein phosphatase 2C family protein Arabidopsis thaliana 31-35 16339784-9 2006 It was also observed that abi1-1 and abi2-1 had increased ABA accumulation. Abscisic Acid 58-61 Protein phosphatase 2C family protein Arabidopsis thaliana 26-32 15197253-2 2004 In this article, we show that PLD alpha 1 and its product, phosphatidic acid (PA), regulate a PP2C, ABI1, which is a negative regulator of ABA responses in Arabidopsis. Abscisic Acid 139-142 Protein phosphatase 2C family protein Arabidopsis thaliana 100-104 15923322-6 2005 Abscisic acid (ABA) signaling mutants (abi1 and abi2) and the UV-sensitive mutant, uvh6, showed the strongest defects in acquired thermotolerance of root growth and seedling survival. Abscisic Acid 0-13 Protein phosphatase 2C family protein Arabidopsis thaliana 39-43 15923322-6 2005 Abscisic acid (ABA) signaling mutants (abi1 and abi2) and the UV-sensitive mutant, uvh6, showed the strongest defects in acquired thermotolerance of root growth and seedling survival. Abscisic Acid 15-18 Protein phosphatase 2C family protein Arabidopsis thaliana 39-43 15197253-9 2004 The lack of ABA-induced production of PA in PLD alpha 1-null cells results in a decrease in the association of ABI1 with the plasma membrane in response to ABA. Abscisic Acid 12-15 Protein phosphatase 2C family protein Arabidopsis thaliana 111-115 15197253-9 2004 The lack of ABA-induced production of PA in PLD alpha 1-null cells results in a decrease in the association of ABI1 with the plasma membrane in response to ABA. Abscisic Acid 156-159 Protein phosphatase 2C family protein Arabidopsis thaliana 111-115 15197253-10 2004 These results indicate that PA produced by PLD alpha 1 inhibits the function of the negative regulator ABI1, thus promoting ABA signaling. Abscisic Acid 124-127 Protein phosphatase 2C family protein Arabidopsis thaliana 103-107 12857845-7 2003 ABA induction of ABI1 and ABI2, negative regulators of ABA signaling, was strongly inhibited by VP1, revealing a second pathway of feed-forward regulation. Abscisic Acid 0-3 Protein phosphatase 2C family protein Arabidopsis thaliana 17-21 15086800-2 2004 Here, we show that the activity of the enzyme responsible for cADPR synthesis, ADP-ribosyl (ADPR) cyclase, is rapidly induced by ABA in both wild-type (WT) and abi1-1 mutant Arabidopsis plants in the absence of protein synthesis. Abscisic Acid 129-132 Protein phosphatase 2C family protein Arabidopsis thaliana 160-166 14576281-5 2003 The stimulation of LKR/SDH protein expression by ABA is regulated by a signal transduction cascade that contains the ABI1-1 and ABI2-1 protein phosphatases. Abscisic Acid 49-52 Protein phosphatase 2C family protein Arabidopsis thaliana 117-123 12857845-7 2003 ABA induction of ABI1 and ABI2, negative regulators of ABA signaling, was strongly inhibited by VP1, revealing a second pathway of feed-forward regulation. Abscisic Acid 55-58 Protein phosphatase 2C family protein Arabidopsis thaliana 17-21 12857845-8 2003 These results indicate that VP1 strongly modifies ABA signaling through feed-forward regulation of ABI1/ABI5-related genes. Abscisic Acid 50-53 Protein phosphatase 2C family protein Arabidopsis thaliana 99-103 12713537-0 2003 The abi1-1 mutation blocks ABA signaling downstream of cADPR action. Abscisic Acid 27-30 Protein phosphatase 2C family protein Arabidopsis thaliana 4-10 12713537-1 2003 Arabidopsis thaliana abscisic acid insensitive 1-1 (abi1-1) is a dominant mutant that is insensitive to the inhibition of germination and growth by the plant hormone, abscisic acid (ABA). Abscisic Acid 21-34 Protein phosphatase 2C family protein Arabidopsis thaliana 52-56 12713537-1 2003 Arabidopsis thaliana abscisic acid insensitive 1-1 (abi1-1) is a dominant mutant that is insensitive to the inhibition of germination and growth by the plant hormone, abscisic acid (ABA). Abscisic Acid 167-180 Protein phosphatase 2C family protein Arabidopsis thaliana 52-56 12713537-1 2003 Arabidopsis thaliana abscisic acid insensitive 1-1 (abi1-1) is a dominant mutant that is insensitive to the inhibition of germination and growth by the plant hormone, abscisic acid (ABA). Abscisic Acid 182-185 Protein phosphatase 2C family protein Arabidopsis thaliana 52-56 12713537-3 2003 However, the site of action of the abi1-1/ABI1 in the ABA signal transduction pathway has not yet been determined. Abscisic Acid 54-57 Protein phosphatase 2C family protein Arabidopsis thaliana 35-41 12713537-3 2003 However, the site of action of the abi1-1/ABI1 in the ABA signal transduction pathway has not yet been determined. Abscisic Acid 54-57 Protein phosphatase 2C family protein Arabidopsis thaliana 42-46 12713537-4 2003 Using single cell assays, we showed that microinjecting mutant abi1-1 protein inhibited the activation of RD29A-GUS and KIN2-GUS in response to ABA, cyclic ADP-ribose (cADPR), and Ca2+. Abscisic Acid 144-147 Protein phosphatase 2C family protein Arabidopsis thaliana 63-69 12713537-7 2003 Moreover, transgenic plants overexpressing abi1-1 were blocked in the induction of ABA-responsive genes; however, overexpression of ABI1 did not affect gene expression. Abscisic Acid 83-86 Protein phosphatase 2C family protein Arabidopsis thaliana 43-49 12713537-8 2003 Taken together, our results demonstrate that abi1-1 is likely to be a dominant negative mutation and ABI1 likely acts downstream of cADPR in the ABA-signaling pathway. Abscisic Acid 145-148 Protein phosphatase 2C family protein Arabidopsis thaliana 101-105 12662310-3 2003 Based on germination in the presence of exogenous ABA, the ABI1 and ABI2 phosphatases act at or upstream of the ERA1 farnesyl transferase and the ABI3 and ABI5 transcription factors act at or downstream of ERA1. Abscisic Acid 50-53 Protein phosphatase 2C family protein Arabidopsis thaliana 59-63 12609042-5 2003 Exposure of ABA-insensitive mutants (abi1-1, abi2-1) to excess light resulted in reduced levels of APX2 expression and confirmed a role for ABA in the signalling pathway. Abscisic Acid 12-15 Protein phosphatase 2C family protein Arabidopsis thaliana 37-43 12609042-5 2003 Exposure of ABA-insensitive mutants (abi1-1, abi2-1) to excess light resulted in reduced levels of APX2 expression and confirmed a role for ABA in the signalling pathway. Abscisic Acid 140-143 Protein phosphatase 2C family protein Arabidopsis thaliana 37-43 12369629-10 2002 These results suggest that salt stress up-regulates AtNHX1 expression transcriptionally and the up-regulation is partially dependent on ABA biosynthesis and ABA signaling through ABI1. Abscisic Acid 157-160 Protein phosphatase 2C family protein Arabidopsis thaliana 179-183 12432076-0 2002 Genome-wide gene expression profiling in Arabidopsis thaliana reveals new targets of abscisic acid and largely impaired gene regulation in the abi1-1 mutant. Abscisic Acid 85-98 Protein phosphatase 2C family protein Arabidopsis thaliana 143-149 12432076-3 2002 To study genome-wide ABA-responsive gene expression we applied massively parallel signature sequencing (MPSS) to samples from Arabidopsis thaliana wildtype (WT) and abi1-1 mutant seedlings. Abscisic Acid 21-24 Protein phosphatase 2C family protein Arabidopsis thaliana 165-171 12432076-7 2002 In the ABA-insensitive mutant abi1-1, ABA regulation of about 84.5% and 6.9% of the identified genes was impaired or strongly diminished, respectively; however, 8.6% of the genes remained appropriately regulated. Abscisic Acid 7-10 Protein phosphatase 2C family protein Arabidopsis thaliana 30-36 12432076-7 2002 In the ABA-insensitive mutant abi1-1, ABA regulation of about 84.5% and 6.9% of the identified genes was impaired or strongly diminished, respectively; however, 8.6% of the genes remained appropriately regulated. Abscisic Acid 38-41 Protein phosphatase 2C family protein Arabidopsis thaliana 30-36 12432076-10 2002 Regulation of the majority of the genes by ABA was impaired in the ABA-insensitive mutant abi1-1. Abscisic Acid 43-46 Protein phosphatase 2C family protein Arabidopsis thaliana 90-96 12432076-10 2002 Regulation of the majority of the genes by ABA was impaired in the ABA-insensitive mutant abi1-1. Abscisic Acid 67-70 Protein phosphatase 2C family protein Arabidopsis thaliana 90-96 12432076-11 2002 However, a subset of genes continued to be appropriately regulated by ABA, which suggests the presence of at least two ABA signaling pathways, only one of which is blocked in abi1-1. Abscisic Acid 70-73 Protein phosphatase 2C family protein Arabidopsis thaliana 175-181 12432076-11 2002 However, a subset of genes continued to be appropriately regulated by ABA, which suggests the presence of at least two ABA signaling pathways, only one of which is blocked in abi1-1. Abscisic Acid 119-122 Protein phosphatase 2C family protein Arabidopsis thaliana 175-181 12369629-9 2002 ABA-induced AtNHX1 expression was also decreased in abi1-1 but not in abi2-1. Abscisic Acid 0-3 Protein phosphatase 2C family protein Arabidopsis thaliana 52-56 11842171-7 2002 In addition, the ethylene-insensitive mutant etr-1, the ABA-insensitive mutant abi-1, and a transgenic line expressing nahG (consequently inhibited in SA production) showed increased susceptibility to heat. Abscisic Acid 56-59 Protein phosphatase 2C family protein Arabidopsis thaliana 79-84 12065416-3 2002 By analysing proteins capable of interacting with ABI1, we have identified the homeodomain protein ATHB6 as a regulator of the ABA signal pathway. Abscisic Acid 127-130 Protein phosphatase 2C family protein Arabidopsis thaliana 50-54 12065416-6 2002 In addition, transgenic plants containing a luciferase gene controlled by the ATHB6 promoter documented a strong ABA-inducible expression of the reporter which was abrogated in the ABA-insensitive abi1 mutant. Abscisic Acid 113-116 Protein phosphatase 2C family protein Arabidopsis thaliana 197-201 12065416-6 2002 In addition, transgenic plants containing a luciferase gene controlled by the ATHB6 promoter documented a strong ABA-inducible expression of the reporter which was abrogated in the ABA-insensitive abi1 mutant. Abscisic Acid 181-184 Protein phosphatase 2C family protein Arabidopsis thaliana 197-201 11779861-10 2002 This feedback regulation by ABA is impaired in the ABA-insensitive mutant abi1 but not in abi2. Abscisic Acid 28-31 Protein phosphatase 2C family protein Arabidopsis thaliana 74-78 11779861-10 2002 This feedback regulation by ABA is impaired in the ABA-insensitive mutant abi1 but not in abi2. Abscisic Acid 51-54 Protein phosphatase 2C family protein Arabidopsis thaliana 74-78 9448270-2 1998 Here, I present mutational analysis of two Arabidopsis thaliana PP2Cs, encoded by ABI1 and AtPP2C, involved in the plant stress hormone abscisic acid (ABA) signaling in maize mesophyll protoplasts. Abscisic Acid 136-149 Protein phosphatase 2C family protein Arabidopsis thaliana 82-86 11587514-5 2001 The ABA induction of embryogenesis genes is highly inhibited in the presence of a mutated protein phosphatase 2C, encoded by the abi1-1 dominant mutant gene that is known to block ABA responses in Arabidopsis. Abscisic Acid 4-7 Protein phosphatase 2C family protein Arabidopsis thaliana 129-133 11587514-5 2001 The ABA induction of embryogenesis genes is highly inhibited in the presence of a mutated protein phosphatase 2C, encoded by the abi1-1 dominant mutant gene that is known to block ABA responses in Arabidopsis. Abscisic Acid 180-183 Protein phosphatase 2C family protein Arabidopsis thaliana 129-133 11587514-8 2001 Therefore, it appears that ABA induction and suppression follow two separate signal transduction pathways with the former inhibited by ABI1 and the latter modulated by PKABA1. Abscisic Acid 27-30 Protein phosphatase 2C family protein Arabidopsis thaliana 135-139 11208021-0 2001 The ABI1 and ABI2 protein phosphatases 2C act in a negative feedback regulatory loop of the abscisic acid signalling pathway. Abscisic Acid 92-105 Protein phosphatase 2C family protein Arabidopsis thaliana 4-8 11208021-2 2001 These genes have been originally identified by the dominant mutations abi1--1 and abi2--1, which reduce the plant"s responsiveness to the hormone abscisic acid (ABA). Abscisic Acid 146-159 Protein phosphatase 2C family protein Arabidopsis thaliana 70-77 11208021-2 2001 These genes have been originally identified by the dominant mutations abi1--1 and abi2--1, which reduce the plant"s responsiveness to the hormone abscisic acid (ABA). Abscisic Acid 161-164 Protein phosphatase 2C family protein Arabidopsis thaliana 70-77 11208021-3 2001 However, recessive mutants of ABI1 were recently shown to be supersensitive to ABA, which demonstrated that the ABI1 phosphatase is a negative regulator of ABA signalling. Abscisic Acid 79-82 Protein phosphatase 2C family protein Arabidopsis thaliana 30-34 11208021-3 2001 However, recessive mutants of ABI1 were recently shown to be supersensitive to ABA, which demonstrated that the ABI1 phosphatase is a negative regulator of ABA signalling. Abscisic Acid 79-82 Protein phosphatase 2C family protein Arabidopsis thaliana 112-116 11208021-3 2001 However, recessive mutants of ABI1 were recently shown to be supersensitive to ABA, which demonstrated that the ABI1 phosphatase is a negative regulator of ABA signalling. Abscisic Acid 156-159 Protein phosphatase 2C family protein Arabidopsis thaliana 30-34 11208021-3 2001 However, recessive mutants of ABI1 were recently shown to be supersensitive to ABA, which demonstrated that the ABI1 phosphatase is a negative regulator of ABA signalling. Abscisic Acid 156-159 Protein phosphatase 2C family protein Arabidopsis thaliana 112-116 11208021-7 2001 However, doubly mutant plants combining the abi2--1R1 allele and a loss-of-function allele at the ABI1 locus were more responsive to ABA than each of the parental single mutants. Abscisic Acid 133-136 Protein phosphatase 2C family protein Arabidopsis thaliana 98-102 11208021-8 2001 These data indicate that the wild-type ABI2 phosphatase is a negative regulator of ABA signalling, and that the ABI1 and ABI2 phosphatases have overlapping roles in controlling ABA action. Abscisic Acid 177-180 Protein phosphatase 2C family protein Arabidopsis thaliana 112-116 11208021-9 2001 Measurements of PP2C activity in plant extracts showed that the phosphatase activity of ABI1 and ABI2 increases in response to ABA. Abscisic Acid 127-130 Protein phosphatase 2C family protein Arabidopsis thaliana 88-92 11208021-10 2001 These results suggest that ABI1 and ABI2 act in a negative feedback regulatory loop of the ABA signalling pathway. Abscisic Acid 91-94 Protein phosphatase 2C family protein Arabidopsis thaliana 27-31 11005831-6 2000 AREB1 and AREB2 required ABA for their activation, because their transactivation activities were repressed in aba2 and abi1 mutants and enhanced in an era1 mutant. Abscisic Acid 25-28 Protein phosphatase 2C family protein Arabidopsis thaliana 119-123 10938371-0 2000 Trivalent ions activate abscisic acid-inducible promoters through an ABI1-dependent pathway in rice protoplasts. Abscisic Acid 24-37 Protein phosphatase 2C family protein Arabidopsis thaliana 69-73 10938371-5 2000 We show in two complementary transient ABA-inducible gene expression assays (beta-glucuronidase and luciferase enzymatic activities and quantitative flow cytometry of green fluorescent protein) that trivalent ions specifically interact with an ABI1-dependent ABA-signaling pathway leading to gene expression. Abscisic Acid 39-42 Protein phosphatase 2C family protein Arabidopsis thaliana 244-248 10938371-5 2000 We show in two complementary transient ABA-inducible gene expression assays (beta-glucuronidase and luciferase enzymatic activities and quantitative flow cytometry of green fluorescent protein) that trivalent ions specifically interact with an ABI1-dependent ABA-signaling pathway leading to gene expression. Abscisic Acid 259-262 Protein phosphatase 2C family protein Arabidopsis thaliana 244-248 10872217-0 2000 The genes ABI1 and ABI2 are involved in abscisic acid- and drought-inducible expression of the Daucus carota L. Dc3 promoter in guard cells of transgenic Arabidopsis thaliana (L.) Heynh. Abscisic Acid 40-53 Protein phosphatase 2C family protein Arabidopsis thaliana 10-14 10872217-1 2000 The ABA INSENSITIVE1 (ABI1) and ABI2 genes encode homologous type-2C protein phosphatases with redundant yet distinct functions in abscisic acid (ABA) responses. Abscisic Acid 4-7 Protein phosphatase 2C family protein Arabidopsis thaliana 22-26 10872217-1 2000 The ABA INSENSITIVE1 (ABI1) and ABI2 genes encode homologous type-2C protein phosphatases with redundant yet distinct functions in abscisic acid (ABA) responses. Abscisic Acid 131-144 Protein phosphatase 2C family protein Arabidopsis thaliana 22-26 10872217-1 2000 The ABA INSENSITIVE1 (ABI1) and ABI2 genes encode homologous type-2C protein phosphatases with redundant yet distinct functions in abscisic acid (ABA) responses. Abscisic Acid 146-149 Protein phosphatase 2C family protein Arabidopsis thaliana 22-26 10872217-2 2000 Results from Northern blot analysis showed that ABA- and mannitol-inducible expression of the COR47 and COR78/LTI78/RD29A (COR78) genes was more impaired in the abi2 mutant of Arabidopsis thaliana (L.) Heynh than in the abi1 mutant. Abscisic Acid 48-51 Protein phosphatase 2C family protein Arabidopsis thaliana 220-224 10521520-0 1999 ABI1 protein phosphatase 2C is a negative regulator of abscisic acid signaling. Abscisic Acid 55-68 Protein phosphatase 2C family protein Arabidopsis thaliana 0-4 10521520-2 1999 In Arabidopsis, the ABI1 gene encodes a member of the 2C class of protein serine/threonine phosphatases (PP2C), and the abi1-1 mutation markedly reduces ABA responsiveness in both seeds and vegetative tissues. Abscisic Acid 153-156 Protein phosphatase 2C family protein Arabidopsis thaliana 20-24 10521520-2 1999 In Arabidopsis, the ABI1 gene encodes a member of the 2C class of protein serine/threonine phosphatases (PP2C), and the abi1-1 mutation markedly reduces ABA responsiveness in both seeds and vegetative tissues. Abscisic Acid 153-156 Protein phosphatase 2C family protein Arabidopsis thaliana 120-126 10521520-4 1999 Hence, it remained unclear whether ABI1 contributes to ABA signaling, and in case ABI1 does regulate ABA responsiveness, whether it is a positive or negative regulator of ABA action. Abscisic Acid 101-104 Protein phosphatase 2C family protein Arabidopsis thaliana 82-86 10521520-4 1999 Hence, it remained unclear whether ABI1 contributes to ABA signaling, and in case ABI1 does regulate ABA responsiveness, whether it is a positive or negative regulator of ABA action. Abscisic Acid 101-104 Protein phosphatase 2C family protein Arabidopsis thaliana 82-86 10521520-6 1999 In contrast to the ABA-resistant abi1-1 mutant, these revertants were more sensitive than the wild type to the inhibition of seed germination and seedling root growth by applied ABA. Abscisic Acid 19-22 Protein phosphatase 2C family protein Arabidopsis thaliana 33-37 10521520-6 1999 In contrast to the ABA-resistant abi1-1 mutant, these revertants were more sensitive than the wild type to the inhibition of seed germination and seedling root growth by applied ABA. Abscisic Acid 178-181 Protein phosphatase 2C family protein Arabidopsis thaliana 33-37 9869399-5 1998 For instance, the ABI1/ABI2 PP2Cs are central components in abscisic acid (ABA) signal transduction. Abscisic Acid 60-73 Protein phosphatase 2C family protein Arabidopsis thaliana 18-22 9869399-5 1998 For instance, the ABI1/ABI2 PP2Cs are central components in abscisic acid (ABA) signal transduction. Abscisic Acid 75-78 Protein phosphatase 2C family protein Arabidopsis thaliana 18-22 9869399-6 1998 Arabidopsis mutants containing a single amino acid exchange in ABI1 or ABI2 show a reduced response to ABA. Abscisic Acid 103-106 Protein phosphatase 2C family protein Arabidopsis thaliana 63-67 9807815-6 1998 Expression of the abi1-1 dominant mutation blocked accumulation of the drought-induced TAS14 and LE25 mRNAs in response to ABA, as well as ABA- and wound-induced expression of the defense-associated pin2 and LAP transcripts. Abscisic Acid 123-126 Protein phosphatase 2C family protein Arabidopsis thaliana 18-24 9807815-6 1998 Expression of the abi1-1 dominant mutation blocked accumulation of the drought-induced TAS14 and LE25 mRNAs in response to ABA, as well as ABA- and wound-induced expression of the defense-associated pin2 and LAP transcripts. Abscisic Acid 139-142 Protein phosphatase 2C family protein Arabidopsis thaliana 18-24 9807815-8 1998 These results indicate that abi1-1 inhibits wound-induced expression of the pin2 and LAP transcripts by blocking ABA-induction of these genes. Abscisic Acid 113-116 Protein phosphatase 2C family protein Arabidopsis thaliana 28-34 9807815-9 1998 This implicates ABI1 in wound-signalling and suggests that a common early ABA signalling pathway may function in the responses to wounding and water stress. Abscisic Acid 74-77 Protein phosphatase 2C family protein Arabidopsis thaliana 16-20 9611170-4 1998 Here, we describe a screen for suppressors of the ABA-insensitive mutant ABI1-1 that enriches for GA auxotrophs and GA-insensitive mutants. Abscisic Acid 50-53 Protein phosphatase 2C family protein Arabidopsis thaliana 73-77 9537523-4 1998 In the ABA-insensitive mutant abi1 of Arabidopsis thaliana a single amino acid exchange in the primary structure results in both a dominant insensitive phenotype and a strongly reduced protein phosphatase activity in vitro by possibly impairing metal ion coordination. Abscisic Acid 7-10 Protein phosphatase 2C family protein Arabidopsis thaliana 30-34 11728469-2 2001 ABI1 is a PP2C of Arabidopsis that exerts negative control on signalling of the phytohormone abscissic acid (ABA). Abscisic Acid 93-107 Protein phosphatase 2C family protein Arabidopsis thaliana 0-4 11728469-2 2001 ABI1 is a PP2C of Arabidopsis that exerts negative control on signalling of the phytohormone abscissic acid (ABA). Abscisic Acid 109-112 Protein phosphatase 2C family protein Arabidopsis thaliana 0-4 11728469-3 2001 Characterisation of the redox sensitivity of ABI1 revealed a strong enzymatic inactivation by hydrogen peroxide (H2O2) which has recently been implicated as a secondary messenger of ABA signalling. Abscisic Acid 182-185 Protein phosphatase 2C family protein Arabidopsis thaliana 45-49 10872217-7 2000 The aba1, abi1, and abi2 mutant genotypes had reduced GUS expression in guard cells of cotyledons in response to mannitol, whereas abi1 and abi2 mutants were reduced in ABA-inducible GUS expression, consistent with overlapping ABA- and drought-response pathways. Abscisic Acid 169-172 Protein phosphatase 2C family protein Arabidopsis thaliana 131-135 10787063-6 2000 The abi1 fca-1 and abi2 fca-1 double mutants flowered earlier than fca-1 implying a role for abscisic acid in floral repression. Abscisic Acid 93-106 Protein phosphatase 2C family protein Arabidopsis thaliana 4-14 10521520-8 1999 The revertant alleles were recessive to the wild-type ABI1 allele in enhancing ABA sensitivity, indicating that this ABA-supersensitive phenotype results from a loss of function in ABI1. Abscisic Acid 79-82 Protein phosphatase 2C family protein Arabidopsis thaliana 54-58 10521520-8 1999 The revertant alleles were recessive to the wild-type ABI1 allele in enhancing ABA sensitivity, indicating that this ABA-supersensitive phenotype results from a loss of function in ABI1. Abscisic Acid 79-82 Protein phosphatase 2C family protein Arabidopsis thaliana 181-185 10521520-8 1999 The revertant alleles were recessive to the wild-type ABI1 allele in enhancing ABA sensitivity, indicating that this ABA-supersensitive phenotype results from a loss of function in ABI1. Abscisic Acid 117-120 Protein phosphatase 2C family protein Arabidopsis thaliana 54-58 10521520-8 1999 The revertant alleles were recessive to the wild-type ABI1 allele in enhancing ABA sensitivity, indicating that this ABA-supersensitive phenotype results from a loss of function in ABI1. Abscisic Acid 117-120 Protein phosphatase 2C family protein Arabidopsis thaliana 181-185 10521520-10 1999 These results indicate that a loss of ABI1 PP2C activity leads to an enhanced responsiveness to ABA. Abscisic Acid 96-99 Protein phosphatase 2C family protein Arabidopsis thaliana 38-42 10521520-11 1999 Thus, the wild-type ABI1 phosphatase is a negative regulator of ABA responses. Abscisic Acid 64-67 Protein phosphatase 2C family protein Arabidopsis thaliana 20-24 9468303-3 1998 The ABI2 protein shows 80% amino acid sequence identity to ABI1, a protein phosphatase 2C (PP2C) involved in ABA signaling. Abscisic Acid 109-112 Protein phosphatase 2C family protein Arabidopsis thaliana 59-63 9448270-2 1998 Here, I present mutational analysis of two Arabidopsis thaliana PP2Cs, encoded by ABI1 and AtPP2C, involved in the plant stress hormone abscisic acid (ABA) signaling in maize mesophyll protoplasts. Abscisic Acid 151-154 Protein phosphatase 2C family protein Arabidopsis thaliana 82-86 9090884-0 1997 Differential abscisic acid regulation of guard cell slow anion channels in Arabidopsis wild-type and abi1 and abi2 mutants. Abscisic Acid 13-26 Protein phosphatase 2C family protein Arabidopsis thaliana 101-105 9276963-1 1997 We show that guard cells from Arabidopsis thaliana plants carrying the abscisic acid-insensitive mutations abi1 and abi2 fail to respond to CO2 and extracellular calcium. Abscisic Acid 71-84 Protein phosphatase 2C family protein Arabidopsis thaliana 107-111 9165752-0 1997 The Arabidopsis ABSCISIC ACID-INSENSITIVE2 (ABI2) and ABI1 genes encode homologous protein phosphatases 2C involved in abscisic acid signal transduction. Abscisic Acid 119-132 Protein phosphatase 2C family protein Arabidopsis thaliana 54-58 9165752-2 1997 In Arabidopsis, the ABA-INSENSITIVE1 (ABI1) protein phosphatase 2C is required for proper ABA responsiveness both in seeds and in vegetative tissues. Abscisic Acid 20-23 Protein phosphatase 2C family protein Arabidopsis thaliana 38-42 9165752-9 1997 Thus, the homologous ABI1 and ABI2 phosphatases appear to assume partially redundant functions in ABA signaling, which may provide a mechanism to maintain informational homeostasis. Abscisic Acid 98-101 Protein phosphatase 2C family protein Arabidopsis thaliana 21-25 9161030-0 1997 Interactions between the ABI1 and the ectopically expressed ABI3 genes in controlling abscisic acid responses in Arabidopsis vegetative tissues. Abscisic Acid 86-99 Protein phosphatase 2C family protein Arabidopsis thaliana 25-29 9161030-1 1997 In Arabidopsis, the abscisic acid (ABA)-Insensitive ABI1 and ABI3 genes have been proposed to act in separate ABA signalling cascades. Abscisic Acid 20-33 Protein phosphatase 2C family protein Arabidopsis thaliana 52-56 9161030-1 1997 In Arabidopsis, the abscisic acid (ABA)-Insensitive ABI1 and ABI3 genes have been proposed to act in separate ABA signalling cascades. Abscisic Acid 35-38 Protein phosphatase 2C family protein Arabidopsis thaliana 52-56 9161030-1 1997 In Arabidopsis, the abscisic acid (ABA)-Insensitive ABI1 and ABI3 genes have been proposed to act in separate ABA signalling cascades. Abscisic Acid 110-113 Protein phosphatase 2C family protein Arabidopsis thaliana 52-56 9161030-2 1997 Recessive mutations in ABI3 alter various physiological processes during seed development, whereas the dominant abi1 mutation inhibits ABA responses largely in vegetative tissues. Abscisic Acid 135-138 Protein phosphatase 2C family protein Arabidopsis thaliana 112-116 9161030-4 1997 Genetic interactions between the ectopically expressed ABI3 and endogenous ABI1 genes were investigated by monitoring diverse ABA responses in vegetative tissues. Abscisic Acid 126-129 Protein phosphatase 2C family protein Arabidopsis thaliana 75-79 9161030-5 1997 Ectopic expression of ABI3 conferred to plantlets the ability to accumulate the seed-specific At2S33 and AtEm1 mRNAs in response to ABA, and the abi1 mutation inhibited this ABI3-dependent induction of AtEm1 by ABA. Abscisic Acid 211-214 Protein phosphatase 2C family protein Arabidopsis thaliana 145-149 9161030-9 1997 The present data demonstrate that ABI1 and ABI3 genetically interact in controlling diverse ABA responses in transgenic vegetative tissues. Abscisic Acid 92-95 Protein phosphatase 2C family protein Arabidopsis thaliana 34-38 9161030-10 1997 The possibility that the endogenous ABI1 and ABI3 genes may similarly act in a common ABA signalling pathway in seed is discussed with previous phenotypic studies of the abi1 and abi3 mutants. Abscisic Acid 86-89 Protein phosphatase 2C family protein Arabidopsis thaliana 36-40 9161030-10 1997 The possibility that the endogenous ABI1 and ABI3 genes may similarly act in a common ABA signalling pathway in seed is discussed with previous phenotypic studies of the abi1 and abi3 mutants. Abscisic Acid 86-89 Protein phosphatase 2C family protein Arabidopsis thaliana 170-174 9108297-5 1997 Thus, ABA-treated abi1-1 mutant plants accumulated less proline than the ABA-treated wild type. Abscisic Acid 6-9 Protein phosphatase 2C family protein Arabidopsis thaliana 18-24 9108297-5 1997 Thus, ABA-treated abi1-1 mutant plants accumulated less proline than the ABA-treated wild type. Abscisic Acid 73-76 Protein phosphatase 2C family protein Arabidopsis thaliana 18-24 9108297-6 1997 Upon salt stress, proline accumulated to a lesser extent in aba1-1 and abi1-1 mutant plants, suggesting an indirect role of ABA on proline accumulation during salt adaptation of the plant. Abscisic Acid 124-127 Protein phosphatase 2C family protein Arabidopsis thaliana 71-77 10645425-1 1998 The semi-dominant abi1-1 mutation of Arabidopsis interferes with multiple aspects of abscisic acid signal transduction resulting in reduced seed dormancy and sensitivity of root growth in ABA. Abscisic Acid 85-98 Protein phosphatase 2C family protein Arabidopsis thaliana 18-22 10645425-1 1998 The semi-dominant abi1-1 mutation of Arabidopsis interferes with multiple aspects of abscisic acid signal transduction resulting in reduced seed dormancy and sensitivity of root growth in ABA. Abscisic Acid 188-191 Protein phosphatase 2C family protein Arabidopsis thaliana 18-22 9090884-8 1997 These data provide cell biological evidence that the abi2 locus disrupts early ABA signaling, that abi1 and abi2 affect ABA signaling at different steps in the cascade, and that protein kinases act as negative regulators of ABA signaling in Arabidopsis. Abscisic Acid 120-123 Protein phosphatase 2C family protein Arabidopsis thaliana 99-103 9090884-8 1997 These data provide cell biological evidence that the abi2 locus disrupts early ABA signaling, that abi1 and abi2 affect ABA signaling at different steps in the cascade, and that protein kinases act as negative regulators of ABA signaling in Arabidopsis. Abscisic Acid 120-123 Protein phosphatase 2C family protein Arabidopsis thaliana 99-103 8898906-1 1996 Mutations at the ABI1 (abscisic acid insensitive 1) locus of the plant Arabidopsis thaliana cause a reduction in sensitivity to the plant hormone abscisic acid. Abscisic Acid 23-36 Protein phosphatase 2C family protein Arabidopsis thaliana 17-21 8197457-2 1994 All three responses are affected in the ABA-insensitive mutant abi1 of Arabidopsis thaliana, suggesting that an early step in the signaling of ABA is controlled by the ABI1 locus. Abscisic Acid 40-43 Protein phosphatase 2C family protein Arabidopsis thaliana 63-67 7910981-0 1994 Arabidopsis ABA response gene ABI1: features of a calcium-modulated protein phosphatase. Abscisic Acid 12-15 Protein phosphatase 2C family protein Arabidopsis thaliana 30-34 7910981-1 1994 The Arabidopsis ABI1 locus is essential for a wide spectrum of abscisic acid (ABA) responses throughout plant development. Abscisic Acid 63-76 Protein phosphatase 2C family protein Arabidopsis thaliana 16-20 7910981-1 1994 The Arabidopsis ABI1 locus is essential for a wide spectrum of abscisic acid (ABA) responses throughout plant development. Abscisic Acid 78-81 Protein phosphatase 2C family protein Arabidopsis thaliana 16-20 7910981-5 1994 These results suggest that the ABI1 protein is a Ca(2+)-modulated phosphatase and functions to integrate ABA and Ca2+ signals with phosphorylation-dependent response pathways. Abscisic Acid 105-108 Protein phosphatase 2C family protein Arabidopsis thaliana 31-35 8771791-7 1996 In the abi1 mutant, however, induction was impaired as 100-fold higher concentrations of ABA were required for a maximum induction as compared with wild-type. Abscisic Acid 89-92 Protein phosphatase 2C family protein Arabidopsis thaliana 7-11 8771791-9 1996 These results indicate that ATHB-7 is transcriptionally regulated in an ABA-dependent manner and may act in a signal transduction pathway which mediates a drought response and also includes ABI1. Abscisic Acid 72-75 Protein phosphatase 2C family protein Arabidopsis thaliana 190-194 7568166-0 1995 Sensitivity to abscisic acid of guard-cell K+ channels is suppressed by abi1-1, a mutant Arabidopsis gene encoding a putative protein phosphatase. Abscisic Acid 15-28 Protein phosphatase 2C family protein Arabidopsis thaliana 72-78 7568166-2 1995 Disruption of ABA sensitivity in wilty abi1-1 mutants of Arabidopsis and evidence that this gene encodes a protein phosphatase suggest that protein (de)-phosphorylation contributes to guard-cell transport control by ABA. Abscisic Acid 14-17 Protein phosphatase 2C family protein Arabidopsis thaliana 39-43 12232276-3 1994 The effects of the abi1 and abi2 mutations on ABA sensitivity of seed germination ranged from recessive to nearly fully dominant, depending on the parental source of the mutant allele. Abscisic Acid 46-49 Protein phosphatase 2C family protein Arabidopsis thaliana 19-23 8197457-2 1994 All three responses are affected in the ABA-insensitive mutant abi1 of Arabidopsis thaliana, suggesting that an early step in the signaling of ABA is controlled by the ABI1 locus. Abscisic Acid 40-43 Protein phosphatase 2C family protein Arabidopsis thaliana 168-172 8197457-2 1994 All three responses are affected in the ABA-insensitive mutant abi1 of Arabidopsis thaliana, suggesting that an early step in the signaling of ABA is controlled by the ABI1 locus. Abscisic Acid 143-146 Protein phosphatase 2C family protein Arabidopsis thaliana 63-67 8197457-2 1994 All three responses are affected in the ABA-insensitive mutant abi1 of Arabidopsis thaliana, suggesting that an early step in the signaling of ABA is controlled by the ABI1 locus. Abscisic Acid 143-146 Protein phosphatase 2C family protein Arabidopsis thaliana 168-172 8018874-7 1994 Wilting and ABA independently induced A1494 expression as evidenced by the effects of ABA and wilting on the ABA-deficient aba-1 and ABA-insensitive abi-1 and abi-3 genotypes. Abscisic Acid 12-15 Protein phosphatase 2C family protein Arabidopsis thaliana 149-154 16668460-3 1991 Similar experiments with mutants that lack seed dormancy due to a reduced sensitivity to abscisic acid (abi) have shown that abi1 and abi3 no longer require GA for germination. Abscisic Acid 89-102 Protein phosphatase 2C family protein Arabidopsis thaliana 125-129 1834244-7 1991 Our data indicate that the ABA-induced expression of three ABA-regulated Arabidopsis cor genes was unaffected in the abi2, abi3, and aba-1 mutants, but was dramatically impaired in the abi1 mutant. Abscisic Acid 27-30 Protein phosphatase 2C family protein Arabidopsis thaliana 185-189 1834244-7 1991 Our data indicate that the ABA-induced expression of three ABA-regulated Arabidopsis cor genes was unaffected in the abi2, abi3, and aba-1 mutants, but was dramatically impaired in the abi1 mutant. Abscisic Acid 59-62 Protein phosphatase 2C family protein Arabidopsis thaliana 185-189 12232124-7 1994 However, this DRI was dramatically reduced in the abscisic acid (ABA)-deficient aba, ABA-insensitive abi1-1, and auxin-resistant axr1-3 mutants. Abscisic Acid 65-68 Protein phosphatase 2C family protein Arabidopsis thaliana 101-105 8492808-3 1993 In contrast, the abi1 and abi2 mutants showed a very slight reduction of ABA inducibility in 8-day-old plants, while the responses of aba and abi3 mutants were comparable to that of wild type. Abscisic Acid 73-76 Protein phosphatase 2C family protein Arabidopsis thaliana 17-21 1463831-4 1992 This stress-related accumulation of the rab18 mRNA is markedly decreased in the ABA-synthesis mutant aba-1, the ABA-response mutant abi-1 or in wild-type plants treated with the carotenoid synthesis inhibitor, fluridone. Abscisic Acid 112-115 Protein phosphatase 2C family protein Arabidopsis thaliana 132-137 16668460-3 1991 Similar experiments with mutants that lack seed dormancy due to a reduced sensitivity to abscisic acid (abi) have shown that abi1 and abi3 no longer require GA for germination. Abscisic Acid 104-107 Protein phosphatase 2C family protein Arabidopsis thaliana 125-129 1688209-10 1991 In order to use the system to isolate genes involved in the signal transduction of abscisic acid, we fine-mapped the mutant loci abi-1 and abi-2, which confer abscisic acid insensitivity, relative to RFLPs and isolated the corresponding YACs. Abscisic Acid 83-96 Protein phosphatase 2C family protein Arabidopsis thaliana 129-134 1830821-6 1991 The induction by ABA is abolished in the ABA-insensitive mutant abi-1 indicating that the abi-1 mutation defines a component in the ABA response pathway. Abscisic Acid 17-20 Protein phosphatase 2C family protein Arabidopsis thaliana 64-69 1830821-6 1991 The induction by ABA is abolished in the ABA-insensitive mutant abi-1 indicating that the abi-1 mutation defines a component in the ABA response pathway. Abscisic Acid 17-20 Protein phosphatase 2C family protein Arabidopsis thaliana 90-95 1830821-6 1991 The induction by ABA is abolished in the ABA-insensitive mutant abi-1 indicating that the abi-1 mutation defines a component in the ABA response pathway. Abscisic Acid 41-44 Protein phosphatase 2C family protein Arabidopsis thaliana 64-69 1830821-6 1991 The induction by ABA is abolished in the ABA-insensitive mutant abi-1 indicating that the abi-1 mutation defines a component in the ABA response pathway. Abscisic Acid 41-44 Protein phosphatase 2C family protein Arabidopsis thaliana 90-95 1830821-6 1991 The induction by ABA is abolished in the ABA-insensitive mutant abi-1 indicating that the abi-1 mutation defines a component in the ABA response pathway. Abscisic Acid 41-44 Protein phosphatase 2C family protein Arabidopsis thaliana 64-69 1830821-6 1991 The induction by ABA is abolished in the ABA-insensitive mutant abi-1 indicating that the abi-1 mutation defines a component in the ABA response pathway. Abscisic Acid 41-44 Protein phosphatase 2C family protein Arabidopsis thaliana 90-95 1688209-10 1991 In order to use the system to isolate genes involved in the signal transduction of abscisic acid, we fine-mapped the mutant loci abi-1 and abi-2, which confer abscisic acid insensitivity, relative to RFLPs and isolated the corresponding YACs. Abscisic Acid 159-172 Protein phosphatase 2C family protein Arabidopsis thaliana 129-134 34932819-8 2022 Our results reveal that ABA signaling regulates actin reorganization to maintain stomatal closure during drought stress and the feedback regulation of PYL1, ABI1 and ABI2 by the CKL2 kinase might fine-tune ABA signaling and affect plant ABA responses. Abscisic Acid 24-27 Protein phosphatase 2C family protein Arabidopsis thaliana 157-161 16667813-1 1990 Wild type and three abscisic acid (ABA)-insensitive mutants of Arabidopsis (ABI1, ABI2, and ABI3) were compared for their ability to respond to ABA for a variety of ABA-inducible responses throughout the life cycle of the plants. Abscisic Acid 144-147 Protein phosphatase 2C family protein Arabidopsis thaliana 76-80 16667813-1 1990 Wild type and three abscisic acid (ABA)-insensitive mutants of Arabidopsis (ABI1, ABI2, and ABI3) were compared for their ability to respond to ABA for a variety of ABA-inducible responses throughout the life cycle of the plants. Abscisic Acid 144-147 Protein phosphatase 2C family protein Arabidopsis thaliana 76-80 16667813-3 1990 The abi1 and abi2 mutants showed reduced sensitivity to ABA for inhibition of seedling growth, induction of proline accumulation, and alterations in protein synthesis patterns during vegetative growth, but had wild type levels of storage reserves. Abscisic Acid 56-59 Protein phosphatase 2C family protein Arabidopsis thaliana 4-8 34932819-8 2022 Our results reveal that ABA signaling regulates actin reorganization to maintain stomatal closure during drought stress and the feedback regulation of PYL1, ABI1 and ABI2 by the CKL2 kinase might fine-tune ABA signaling and affect plant ABA responses. Abscisic Acid 206-209 Protein phosphatase 2C family protein Arabidopsis thaliana 157-161 34932819-8 2022 Our results reveal that ABA signaling regulates actin reorganization to maintain stomatal closure during drought stress and the feedback regulation of PYL1, ABI1 and ABI2 by the CKL2 kinase might fine-tune ABA signaling and affect plant ABA responses. Abscisic Acid 237-240 Protein phosphatase 2C family protein Arabidopsis thaliana 157-161 34386031-7 2021 Furthermore, m6A sequencing showed that ABA signaling genes, including PYR1, PYL7, PYL9, ABI1, and SnRK2.2 are m6A hypermethylated in alkbh10b-1 after ABA treatment. Abscisic Acid 40-43 Protein phosphatase 2C family protein Arabidopsis thaliana 89-93 34386031-7 2021 Furthermore, m6A sequencing showed that ABA signaling genes, including PYR1, PYL7, PYL9, ABI1, and SnRK2.2 are m6A hypermethylated in alkbh10b-1 after ABA treatment. Abscisic Acid 151-154 Protein phosphatase 2C family protein Arabidopsis thaliana 89-93 34281207-2 2021 To understand the role of miRNAs in the response to ABA, ABA-responsive miRNAs were identified by small RNA sequencing in wild-type Arabidopsis, as well as in abi1td, mkkk17, and mkkk18 mutants. Abscisic Acid 52-55 Protein phosphatase 2C family protein Arabidopsis thaliana 159-163 34281207-3 2021 We identified 10 novel miRNAs in WT after ABA treatment, while in abi1td, mkkk17, and mkkk18 mutants, three, seven, and nine known miRNAs, respectively, were differentially expressed after ABA treatment. Abscisic Acid 189-192 Protein phosphatase 2C family protein Arabidopsis thaliana 66-70 16666794-1 1989 In Arabidopsis thaliana, seed development in recombinants of the ABA-deficient aba mutant with the ABA response mutants abi1 or abi3 is compared to wild type and the monogenic parents. Abscisic Acid 99-102 Protein phosphatase 2C family protein Arabidopsis thaliana 120-124 34099554-0 2021 TMK1-based auxin signaling regulates abscisic acid responses via phosphorylating ABI1/2 in Arabidopsis. Abscisic Acid 37-50 Protein phosphatase 2C family protein Arabidopsis thaliana 81-87 34099554-4 2021 We show that high auxin and TMK1 play essential and positive roles in ABA signaling through regulating ABA INSENSITIVE 1 and 2 (ABI1/2), two negative regulators of the ABA pathway. Abscisic Acid 70-73 Protein phosphatase 2C family protein Arabidopsis thaliana 103-126 34099554-4 2021 We show that high auxin and TMK1 play essential and positive roles in ABA signaling through regulating ABA INSENSITIVE 1 and 2 (ABI1/2), two negative regulators of the ABA pathway. Abscisic Acid 70-73 Protein phosphatase 2C family protein Arabidopsis thaliana 128-134 34099554-4 2021 We show that high auxin and TMK1 play essential and positive roles in ABA signaling through regulating ABA INSENSITIVE 1 and 2 (ABI1/2), two negative regulators of the ABA pathway. Abscisic Acid 168-171 Protein phosphatase 2C family protein Arabidopsis thaliana 103-126 34099554-4 2021 We show that high auxin and TMK1 play essential and positive roles in ABA signaling through regulating ABA INSENSITIVE 1 and 2 (ABI1/2), two negative regulators of the ABA pathway. Abscisic Acid 168-171 Protein phosphatase 2C family protein Arabidopsis thaliana 128-134 35134199-4 2022 SKIP binds to the pre-mRNA of ABA signaling related genes, such as PYL7, PYL8, ABI1, HAB1, and ABI5, to regulate their splicing. Abscisic Acid 30-33 Protein phosphatase 2C family protein Arabidopsis thaliana 79-83 35388459-7 2022 The phosphor-mimic RCAR12T105D significantly displayed ABA-induced inhibition of the phosphatase ABI1 (ABA insensitive 1) activity, leading to up-regulation of ABA-responsive genes RD29A and RD29B in cark157:RCAR12T105D transgenic plants, which exhibited ABA hypersensitive phenotype. Abscisic Acid 55-58 Protein phosphatase 2C family protein Arabidopsis thaliana 97-101 35388459-7 2022 The phosphor-mimic RCAR12T105D significantly displayed ABA-induced inhibition of the phosphatase ABI1 (ABA insensitive 1) activity, leading to up-regulation of ABA-responsive genes RD29A and RD29B in cark157:RCAR12T105D transgenic plants, which exhibited ABA hypersensitive phenotype. Abscisic Acid 55-58 Protein phosphatase 2C family protein Arabidopsis thaliana 103-120 35388459-7 2022 The phosphor-mimic RCAR12T105D significantly displayed ABA-induced inhibition of the phosphatase ABI1 (ABA insensitive 1) activity, leading to up-regulation of ABA-responsive genes RD29A and RD29B in cark157:RCAR12T105D transgenic plants, which exhibited ABA hypersensitive phenotype. Abscisic Acid 160-163 Protein phosphatase 2C family protein Arabidopsis thaliana 97-101 35388459-7 2022 The phosphor-mimic RCAR12T105D significantly displayed ABA-induced inhibition of the phosphatase ABI1 (ABA insensitive 1) activity, leading to up-regulation of ABA-responsive genes RD29A and RD29B in cark157:RCAR12T105D transgenic plants, which exhibited ABA hypersensitive phenotype. Abscisic Acid 160-163 Protein phosphatase 2C family protein Arabidopsis thaliana 103-120 35388459-7 2022 The phosphor-mimic RCAR12T105D significantly displayed ABA-induced inhibition of the phosphatase ABI1 (ABA insensitive 1) activity, leading to up-regulation of ABA-responsive genes RD29A and RD29B in cark157:RCAR12T105D transgenic plants, which exhibited ABA hypersensitive phenotype. Abscisic Acid 255-258 Protein phosphatase 2C family protein Arabidopsis thaliana 97-101 35388459-7 2022 The phosphor-mimic RCAR12T105D significantly displayed ABA-induced inhibition of the phosphatase ABI1 (ABA insensitive 1) activity, leading to up-regulation of ABA-responsive genes RD29A and RD29B in cark157:RCAR12T105D transgenic plants, which exhibited ABA hypersensitive phenotype. Abscisic Acid 255-258 Protein phosphatase 2C family protein Arabidopsis thaliana 103-120 35610574-7 2022 Furthermore, the expression levels of stress/ABA-responsive marker genes, including ABI1, ABI2, ABI4, ABI5 and RD29B, in the GsERF1 transgenic lines were affected by AlCl3 treatment, unlike those in the wild type. Abscisic Acid 45-48 Protein phosphatase 2C family protein Arabidopsis thaliana 84-88 35548282-0 2022 Brassinosteroid-Insensitive 1-Associated Receptor Kinase 1 Modulates Abscisic Acid Signaling by Inducing PYR1 Monomerization and Association With ABI1 in Arabidopsis. Abscisic Acid 69-82 Protein phosphatase 2C family protein Arabidopsis thaliana 146-150 32933749-4 2020 qRT-PCR assays indicated that NRT1.2 over-production in 7-days-old seedlings up-regulated the expression of ABA-responsive genes: ABI1, ABI2, ABI3, ABI4, ABI5, RAB18, RD29A, and RD29B and PHOSPHOLIPASE Dalpha1 (PLDalpha1). Abscisic Acid 108-111 Protein phosphatase 2C family protein Arabidopsis thaliana 130-134 33048351-9 2021 Mutations in ABI1 and AHG3 partly rescue the cop1 stomatal phenotype and the phosphorylation level of OST1, a crucial SnRK2-type kinase in ABA signaling. Abscisic Acid 139-142 Protein phosphatase 2C family protein Arabidopsis thaliana 13-17 33487349-6 2021 Glucose treatment of the abscisic acid (ABA)-related mutants indicated that glucose-triggered upregulation of FMOGS-OX2 and FMOGS-OX4 was partially regulated by ABA through the key negative regulators ABI1 and ABI2, and the positive regulator SnRK2, but not via the transcription factor ABI5. Abscisic Acid 25-38 Protein phosphatase 2C family protein Arabidopsis thaliana 201-205 33487349-6 2021 Glucose treatment of the abscisic acid (ABA)-related mutants indicated that glucose-triggered upregulation of FMOGS-OX2 and FMOGS-OX4 was partially regulated by ABA through the key negative regulators ABI1 and ABI2, and the positive regulator SnRK2, but not via the transcription factor ABI5. Abscisic Acid 40-43 Protein phosphatase 2C family protein Arabidopsis thaliana 201-205 33487349-6 2021 Glucose treatment of the abscisic acid (ABA)-related mutants indicated that glucose-triggered upregulation of FMOGS-OX2 and FMOGS-OX4 was partially regulated by ABA through the key negative regulators ABI1 and ABI2, and the positive regulator SnRK2, but not via the transcription factor ABI5. Abscisic Acid 161-164 Protein phosphatase 2C family protein Arabidopsis thaliana 201-205 32293270-8 2020 The results suggest that the ABRE-motif was localized in the IbSUT4 promoter region, and the expression of the ABA signaling pathway genes (i.e., ABF2, ABF4, SnRK2.2, SnRK2.3, and PYL8/RCAR3) were induced, and the expression of ABI1 was inhibited. Abscisic Acid 111-114 Protein phosphatase 2C family protein Arabidopsis thaliana 228-232 33077597-0 2020 The UBC27-AIRP3 ubiquitination complex modulates ABA signaling by promoting the degradation of ABI1 in Arabidopsis. Abscisic Acid 49-52 Protein phosphatase 2C family protein Arabidopsis thaliana 95-99 33077597-2 2020 The clade A protein phosphatase 2Cs (PP2Cs) like ABI1 (ABA-INSENSITIVE 1) work as coreceptors of ABA and regulate multiple ABA responses. Abscisic Acid 55-58 Protein phosphatase 2C family protein Arabidopsis thaliana 49-53 33077597-2 2020 The clade A protein phosphatase 2Cs (PP2Cs) like ABI1 (ABA-INSENSITIVE 1) work as coreceptors of ABA and regulate multiple ABA responses. Abscisic Acid 97-100 Protein phosphatase 2C family protein Arabidopsis thaliana 49-53 33077597-2 2020 The clade A protein phosphatase 2Cs (PP2Cs) like ABI1 (ABA-INSENSITIVE 1) work as coreceptors of ABA and regulate multiple ABA responses. Abscisic Acid 97-100 Protein phosphatase 2C family protein Arabidopsis thaliana 55-72 33077597-3 2020 Ubiquitination of ABI1 has been proven to play important regulatory roles in ABA signaling. Abscisic Acid 77-80 Protein phosphatase 2C family protein Arabidopsis thaliana 18-22 33077597-8 2020 ABA activates the expression of UBC27, inhibits the proteasome degradation of UBC27, and enhances the interaction between UBC27 and ABI1 to increase its activity. Abscisic Acid 0-3 Protein phosphatase 2C family protein Arabidopsis thaliana 132-136 32948668-7 2020 In response to ABA, the phenotypes of pp1r3 topp1 topp4-3 and pp1r3 topp4-1 were consistent with those of pp1r3, while pp1r3 abi1-1 showed an additive effect of the pp1r3 and abi1-1 (mutation in Abscisic Acid Insensitive1, ABI1) single mutant. Abscisic Acid 15-18 Protein phosphatase 2C family protein Arabidopsis thaliana 125-129 32948668-7 2020 In response to ABA, the phenotypes of pp1r3 topp1 topp4-3 and pp1r3 topp4-1 were consistent with those of pp1r3, while pp1r3 abi1-1 showed an additive effect of the pp1r3 and abi1-1 (mutation in Abscisic Acid Insensitive1, ABI1) single mutant. Abscisic Acid 15-18 Protein phosphatase 2C family protein Arabidopsis thaliana 175-179 32948668-7 2020 In response to ABA, the phenotypes of pp1r3 topp1 topp4-3 and pp1r3 topp4-1 were consistent with those of pp1r3, while pp1r3 abi1-1 showed an additive effect of the pp1r3 and abi1-1 (mutation in Abscisic Acid Insensitive1, ABI1) single mutant. Abscisic Acid 15-18 Protein phosphatase 2C family protein Arabidopsis thaliana 223-227 32948668-12 2020 Overall, our results suggest that the PP1R3:TOPP holoenzyme functions in parallel with ABI1 in the nucleus to regulate ABA signaling. Abscisic Acid 119-122 Protein phosphatase 2C family protein Arabidopsis thaliana 87-91 32490347-5 2020 Based on these interaction results, we next revealed the signaling cross talk between jasmonate and abscisic acid by characterizing the JAZ1-PYL4 and JAZ1-ABI1 interactions. Abscisic Acid 100-113 Protein phosphatase 2C family protein Arabidopsis thaliana 155-159 32619606-7 2020 ABT interacts with PYR1/PYL/RCAR and PP2C proteins, and interferes with the interaction between PYR1/PYL4 and ABI1/ABI2 and hampers the inhibition of ABI1/ABI2 by ABA-bound PYR1/PYL4, thereby terminates ABA signaling. Abscisic Acid 163-166 Protein phosphatase 2C family protein Arabidopsis thaliana 110-114 32619606-7 2020 ABT interacts with PYR1/PYL/RCAR and PP2C proteins, and interferes with the interaction between PYR1/PYL4 and ABI1/ABI2 and hampers the inhibition of ABI1/ABI2 by ABA-bound PYR1/PYL4, thereby terminates ABA signaling. Abscisic Acid 163-166 Protein phosphatase 2C family protein Arabidopsis thaliana 150-154 32619606-7 2020 ABT interacts with PYR1/PYL/RCAR and PP2C proteins, and interferes with the interaction between PYR1/PYL4 and ABI1/ABI2 and hampers the inhibition of ABI1/ABI2 by ABA-bound PYR1/PYL4, thereby terminates ABA signaling. Abscisic Acid 203-206 Protein phosphatase 2C family protein Arabidopsis thaliana 110-114 32619606-7 2020 ABT interacts with PYR1/PYL/RCAR and PP2C proteins, and interferes with the interaction between PYR1/PYL4 and ABI1/ABI2 and hampers the inhibition of ABI1/ABI2 by ABA-bound PYR1/PYL4, thereby terminates ABA signaling. Abscisic Acid 203-206 Protein phosphatase 2C family protein Arabidopsis thaliana 150-154 32625229-7 2020 Interestingly, ABA inhibited the interaction of SCD2/RRP1 with ABI1, but did not affect the interaction of SCD2/RRP1 with PYR1. Abscisic Acid 15-18 Protein phosphatase 2C family protein Arabidopsis thaliana 63-67 32326656-4 2020 We showed previously that ABI1, a group A protein phosphatase type 2C (PP2C) and a key negative regulator of abscisic acid signaling regulates type I ACS stability. Abscisic Acid 109-122 Protein phosphatase 2C family protein Arabidopsis thaliana 26-30 31708935-6 2019 Bimolecular fluorescence complementation assays showed that AtPR5K2 physically interacted with the type 2C protein phosphatases ABA-insensitive 1 (ABI1) and ABI2 and the SNF1-related protein kinase 2 (SnRK2.6) proteins, all of which are involved in the initiation of abscisic acid (ABA) signaling; however, these interactions were inhibited by treatments of exogenous ABA. Abscisic Acid 267-280 Protein phosphatase 2C family protein Arabidopsis thaliana 128-145 31357236-5 2019 We show that ABI1, a negative regulator in abscisic acid (ABA) signaling, dephosphorylates and destabilizes BIN2 to inhibit BIN2 kinase activity. Abscisic Acid 43-56 Protein phosphatase 2C family protein Arabidopsis thaliana 13-17 31357236-5 2019 We show that ABI1, a negative regulator in abscisic acid (ABA) signaling, dephosphorylates and destabilizes BIN2 to inhibit BIN2 kinase activity. Abscisic Acid 58-61 Protein phosphatase 2C family protein Arabidopsis thaliana 13-17 31708935-6 2019 Bimolecular fluorescence complementation assays showed that AtPR5K2 physically interacted with the type 2C protein phosphatases ABA-insensitive 1 (ABI1) and ABI2 and the SNF1-related protein kinase 2 (SnRK2.6) proteins, all of which are involved in the initiation of abscisic acid (ABA) signaling; however, these interactions were inhibited by treatments of exogenous ABA. Abscisic Acid 267-280 Protein phosphatase 2C family protein Arabidopsis thaliana 147-151 31708935-6 2019 Bimolecular fluorescence complementation assays showed that AtPR5K2 physically interacted with the type 2C protein phosphatases ABA-insensitive 1 (ABI1) and ABI2 and the SNF1-related protein kinase 2 (SnRK2.6) proteins, all of which are involved in the initiation of abscisic acid (ABA) signaling; however, these interactions were inhibited by treatments of exogenous ABA. Abscisic Acid 128-131 Protein phosphatase 2C family protein Arabidopsis thaliana 147-151 31708935-6 2019 Bimolecular fluorescence complementation assays showed that AtPR5K2 physically interacted with the type 2C protein phosphatases ABA-insensitive 1 (ABI1) and ABI2 and the SNF1-related protein kinase 2 (SnRK2.6) proteins, all of which are involved in the initiation of abscisic acid (ABA) signaling; however, these interactions were inhibited by treatments of exogenous ABA. Abscisic Acid 282-285 Protein phosphatase 2C family protein Arabidopsis thaliana 128-145 31708935-6 2019 Bimolecular fluorescence complementation assays showed that AtPR5K2 physically interacted with the type 2C protein phosphatases ABA-insensitive 1 (ABI1) and ABI2 and the SNF1-related protein kinase 2 (SnRK2.6) proteins, all of which are involved in the initiation of abscisic acid (ABA) signaling; however, these interactions were inhibited by treatments of exogenous ABA. Abscisic Acid 282-285 Protein phosphatase 2C family protein Arabidopsis thaliana 147-151 31708935-8 2019 Taken together, these results suggest that AtPR5K2 participates in ABA-dependent drought-stress signaling through the phosphorylation of ABI1 and ABI2. Abscisic Acid 67-70 Protein phosphatase 2C family protein Arabidopsis thaliana 137-141 29288233-2 2018 Here, we show that ABI1, a key negative regulator of ABA signaling, is essential for auxin-modulated root development. Abscisic Acid 53-56 Protein phosphatase 2C family protein Arabidopsis thaliana 19-23 31475026-8 2019 The transgenic lines showed upregulation of the ABA-responsive genes ABI1 (ABA INSENSITIVE 1) and ABI5 and hypersensitivity to ABA. Abscisic Acid 48-51 Protein phosphatase 2C family protein Arabidopsis thaliana 69-73 31475026-8 2019 The transgenic lines showed upregulation of the ABA-responsive genes ABI1 (ABA INSENSITIVE 1) and ABI5 and hypersensitivity to ABA. Abscisic Acid 75-78 Protein phosphatase 2C family protein Arabidopsis thaliana 69-73 31475026-8 2019 The transgenic lines showed upregulation of the ABA-responsive genes ABI1 (ABA INSENSITIVE 1) and ABI5 and hypersensitivity to ABA. Abscisic Acid 75-78 Protein phosphatase 2C family protein Arabidopsis thaliana 69-73 30760853-8 2019 An abscisic-acid-insensitive mutant, abi1, showed altered sensitivity to germination- and root growth-inhibition. Abscisic Acid 3-16 Protein phosphatase 2C family protein Arabidopsis thaliana 37-41 30120350-4 2018 A yeast two-hybrid assay revealed that the interaction between OsABIL2 and a putative rice ABA receptor, OsPYL1, was ABA-dependent, and the interaction was lost with amino acid substitution from glycine to aspartic acid at the 183rd amino acid of the OsABIL2 protein, corresponding to abi1-1 mutation. Abscisic Acid 91-94 Protein phosphatase 2C family protein Arabidopsis thaliana 285-289 30120350-4 2018 A yeast two-hybrid assay revealed that the interaction between OsABIL2 and a putative rice ABA receptor, OsPYL1, was ABA-dependent, and the interaction was lost with amino acid substitution from glycine to aspartic acid at the 183rd amino acid of the OsABIL2 protein, corresponding to abi1-1 mutation. Abscisic Acid 117-120 Protein phosphatase 2C family protein Arabidopsis thaliana 285-289 30120350-7 2018 These results indicated that the introduction of abi1-1 type dominant mutation was also effective in OsABIL2 at decreasing ABA sensitivity in plants, and the attenuation of ABA sensitivity could be an alternative parameter to improve rice performance under low temperatures. Abscisic Acid 123-126 Protein phosphatase 2C family protein Arabidopsis thaliana 49-53 29288233-6 2018 Overexpressed (OX) sHSP22 partially rescued the ABA hypersensitivity of abi1-3 In addition, sHSP22 is involved in auxin-regulated hypocotyl elongation at high temperature treatment. Abscisic Acid 48-51 Protein phosphatase 2C family protein Arabidopsis thaliana 72-76 29288233-9 2018 Our results suggest that sHSP22 regulates auxin response through modulating auxin polar transport, and ABI1-sHSP22 provides a novel module orchestrating ABA and auxin signaling crosstalk in Arabidopsis (Arabidopsis thaliana). Abscisic Acid 153-156 Protein phosphatase 2C family protein Arabidopsis thaliana 103-107 29335506-8 2018 Take ABI1 and ABI2, key negative regulators in ABA signal pathway, as examples, homologous alignment and a phylogenetic tree in various species showed that ABI1 and ABI2 are highly conserved among various species. Abscisic Acid 47-50 Protein phosphatase 2C family protein Arabidopsis thaliana 5-9 29335506-8 2018 Take ABI1 and ABI2, key negative regulators in ABA signal pathway, as examples, homologous alignment and a phylogenetic tree in various species showed that ABI1 and ABI2 are highly conserved among various species. Abscisic Acid 47-50 Protein phosphatase 2C family protein Arabidopsis thaliana 156-160 26974851-4 2016 We proposed that ORA47 acts as a connection between ABA INSENSITIVE1 (ABI1) and ABI2 and mediates an ABI1-ORA47-ABI2 positive feedback loop. Abscisic Acid 52-55 Protein phosphatase 2C family protein Arabidopsis thaliana 70-74 28702742-5 2017 Arabidopsis ABA perception components mutants, abi1-1 and abi2-1, also displayed similar phenotypes to ABA-deficient mutants in resistance to G. cichoracearum. Abscisic Acid 12-15 Protein phosphatase 2C family protein Arabidopsis thaliana 47-53 28702742-5 2017 Arabidopsis ABA perception components mutants, abi1-1 and abi2-1, also displayed similar phenotypes to ABA-deficient mutants in resistance to G. cichoracearum. Abscisic Acid 103-106 Protein phosphatase 2C family protein Arabidopsis thaliana 47-53 28285084-7 2017 Furthermore, several ABA- and salt-related genes, such as NCED3, ABI1 and CBL1, were up-regulated. Abscisic Acid 21-24 Protein phosphatase 2C family protein Arabidopsis thaliana 65-69 27913741-6 2017 The activity of AIK1 is induced by ABA in Arabidopsis and tobacco (Nicotiana benthamiana), and the Arabidopsis protein phosphatase type 2C, ABI1, a negative regulator of ABA signaling, restricts AIK1 activity by dephosphorylation. Abscisic Acid 170-173 Protein phosphatase 2C family protein Arabidopsis thaliana 140-144 27923613-9 2017 Accordingly, RDK1 interacted in the plasma membrane with type 2C protein phosphatase ABSCISIC ACID INSENSITIVE1 (ABI1); this interaction was further enhanced by exogenous application of ABA, suggesting that RDK1-mediated recruitment of ABI1 onto the plasma membrane is important for ABA signaling. Abscisic Acid 186-189 Protein phosphatase 2C family protein Arabidopsis thaliana 85-111 27923613-9 2017 Accordingly, RDK1 interacted in the plasma membrane with type 2C protein phosphatase ABSCISIC ACID INSENSITIVE1 (ABI1); this interaction was further enhanced by exogenous application of ABA, suggesting that RDK1-mediated recruitment of ABI1 onto the plasma membrane is important for ABA signaling. Abscisic Acid 186-189 Protein phosphatase 2C family protein Arabidopsis thaliana 113-117 27923613-9 2017 Accordingly, RDK1 interacted in the plasma membrane with type 2C protein phosphatase ABSCISIC ACID INSENSITIVE1 (ABI1); this interaction was further enhanced by exogenous application of ABA, suggesting that RDK1-mediated recruitment of ABI1 onto the plasma membrane is important for ABA signaling. Abscisic Acid 186-189 Protein phosphatase 2C family protein Arabidopsis thaliana 236-240 27923613-9 2017 Accordingly, RDK1 interacted in the plasma membrane with type 2C protein phosphatase ABSCISIC ACID INSENSITIVE1 (ABI1); this interaction was further enhanced by exogenous application of ABA, suggesting that RDK1-mediated recruitment of ABI1 onto the plasma membrane is important for ABA signaling. Abscisic Acid 283-286 Protein phosphatase 2C family protein Arabidopsis thaliana 85-111 27923613-9 2017 Accordingly, RDK1 interacted in the plasma membrane with type 2C protein phosphatase ABSCISIC ACID INSENSITIVE1 (ABI1); this interaction was further enhanced by exogenous application of ABA, suggesting that RDK1-mediated recruitment of ABI1 onto the plasma membrane is important for ABA signaling. Abscisic Acid 283-286 Protein phosphatase 2C family protein Arabidopsis thaliana 113-117 26974851-4 2016 We proposed that ORA47 acts as a connection between ABA INSENSITIVE1 (ABI1) and ABI2 and mediates an ABI1-ORA47-ABI2 positive feedback loop. Abscisic Acid 52-55 Protein phosphatase 2C family protein Arabidopsis thaliana 101-105 26625868-8 2015 Quantitative RT-PCR results showed that ABA response of several genes involved in ABA signaling, including ABI1, SnRK2.2, SnRK2.3 and SnRK2.6 were altered in the transgenic plants overexpressing bHLH129. Abscisic Acid 40-43 Protein phosphatase 2C family protein Arabidopsis thaliana 107-111 26852793-0 2016 Regulation of Arabidopsis MAPKKK18 by ABI1 and SnRK2, components of the ABA signaling pathway. Abscisic Acid 72-75 Protein phosphatase 2C family protein Arabidopsis thaliana 38-42 26852793-2 2016 We recently discovered that MAPKKK18, an ABA-activated kinase, is regulated by the protein phosphatase type 2C (PP2C) ABI1 and the kinase SnRK2.6, both components of the ABA core signaling pathway. Abscisic Acid 41-44 Protein phosphatase 2C family protein Arabidopsis thaliana 118-122 26625868-8 2015 Quantitative RT-PCR results showed that ABA response of several genes involved in ABA signaling, including ABI1, SnRK2.2, SnRK2.3 and SnRK2.6 were altered in the transgenic plants overexpressing bHLH129. Abscisic Acid 82-85 Protein phosphatase 2C family protein Arabidopsis thaliana 107-111 26482222-7 2015 Introducing the abi1-3 loss-of-function mutation into pub12 pub13 mutant recovers the ABA-insensitive phenotypes of the pub12 pub13 mutant. Abscisic Acid 86-89 Protein phosphatase 2C family protein Arabidopsis thaliana 16-20 26443375-8 2015 Notably, we identified abscisic acid insensitive 1 (ABI1) PP2C as a MKKK18-interacting protein, and demonstrated that ABI1 inhibited its activity. Abscisic Acid 23-36 Protein phosphatase 2C family protein Arabidopsis thaliana 52-56 26443375-8 2015 Notably, we identified abscisic acid insensitive 1 (ABI1) PP2C as a MKKK18-interacting protein, and demonstrated that ABI1 inhibited its activity. Abscisic Acid 23-36 Protein phosphatase 2C family protein Arabidopsis thaliana 118-122