PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19522839-4 2009 By analysing cyp707a1, cyp707a2 and cyp707a3 mutants, we found that CYP707A2 plays a major role in ABA catabolism during the first stage of imbibition. Abscisic Acid 99-102 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 36-44 17582765-0 2007 Effect of the minor ABA metabolite 7"-hydroxy-ABA on Arabidopsis ABA 8"-hydroxylase CYP707A3. Abscisic Acid 20-23 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 84-92 17582774-3 2007 Here we report a structural ABA analogue (AHI1), whose both enantiomers bind to recombinant Arabidopsis CYP707A3, in spite of stereo-structural similarity to ABA. Abscisic Acid 28-31 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 104-112 17582774-5 2007 To explore which moiety is responsible for asymmetrical binding by CYP707A3, we synthesized and tested ABA analogues that lacked each moiety. Abscisic Acid 103-106 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 67-75 17582765-1 2007 To examine the effect of the minor abscisic acid (ABA) metabolite 7"-hydroxy-ABA on Arabidopsis ABA 8"-hydroxylase (CYP707A3), we developed a novel and facile, four-step synthesis of 7"-hydroxy-ABA from alpha-ionone. Abscisic Acid 35-48 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 116-124 17582765-1 2007 To examine the effect of the minor abscisic acid (ABA) metabolite 7"-hydroxy-ABA on Arabidopsis ABA 8"-hydroxylase (CYP707A3), we developed a novel and facile, four-step synthesis of 7"-hydroxy-ABA from alpha-ionone. Abscisic Acid 50-53 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 116-124 16623881-4 2006 A T-DNA insertional cyp707a3-1 mutant contained higher ABA levels in turgid plants, which showed a reduced transpiration rate and hypersensitivity to exogenous ABA during early seedling growth. Abscisic Acid 55-58 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 20-28 16623881-4 2006 A T-DNA insertional cyp707a3-1 mutant contained higher ABA levels in turgid plants, which showed a reduced transpiration rate and hypersensitivity to exogenous ABA during early seedling growth. Abscisic Acid 160-163 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 20-28 16623881-5 2006 On dehydration, the cyp707a3-1 mutant accumulated a higher amount of stress-induced ABA than the wild type, an event that occurred relatively later and was coincident with slow drought induction of CYP707A3. Abscisic Acid 84-87 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 20-28 16623881-6 2006 The cyp707a3 mutant plants exhibited both exaggerated ABA-inducible gene expression and enhanced drought tolerance. Abscisic Acid 54-57 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 4-12 16623881-7 2006 Conversely, constitutive expression of CYP707A3 relieved growth retardation by ABA, increased transpiration, and a reduction of endogenous ABA in both turgid and dehydrated plants. Abscisic Acid 79-82 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 39-47 16623881-7 2006 Conversely, constitutive expression of CYP707A3 relieved growth retardation by ABA, increased transpiration, and a reduction of endogenous ABA in both turgid and dehydrated plants. Abscisic Acid 139-142 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 39-47 16623881-8 2006 Taken together, our results indicate that CYP707A3 plays an important role in determining threshold levels of ABA during dehydration and after rehydration. Abscisic Acid 110-113 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 42-50 33633834-4 2021 By using the ABA 8"-hydroxylase-deficient Arabidopsis thaliana double mutant cyp707a1 cyp707a3, which is unable to break down and instead accumulates high levels of ABA, we reveal the importance of the control of ABA concentration in mediating stomatal responses to CO2 and light. Abscisic Acid 13-16 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 86-94 15848748-2 2005 For designing a specific inhibitor of this enzyme, the substrate specificity and inhibition of CYP707A3, an ABA 8"-hydroxylase from Arabidopsis thaliana, was investigated using 45 structural analogues of ABA and compared to the structural requirements for ABA activity. Abscisic Acid 108-111 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 95-103 15848748-2 2005 For designing a specific inhibitor of this enzyme, the substrate specificity and inhibition of CYP707A3, an ABA 8"-hydroxylase from Arabidopsis thaliana, was investigated using 45 structural analogues of ABA and compared to the structural requirements for ABA activity. Abscisic Acid 204-207 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 95-103 15064374-6 2004 The insect cells expressing CYP707A3 efficiently metabolized (+)-ABA to yield phaseic acid, the isomerized form of 8"-hydroxy-ABA. Abscisic Acid 61-68 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 28-36 15064374-8 2004 The solubilized CYP707A3 protein bound (+)-ABA with the binding constant K(s) = 3.5 microm, but did not bind (-)-ABA. Abscisic Acid 39-46 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 16-24 33633834-4 2021 By using the ABA 8"-hydroxylase-deficient Arabidopsis thaliana double mutant cyp707a1 cyp707a3, which is unable to break down and instead accumulates high levels of ABA, we reveal the importance of the control of ABA concentration in mediating stomatal responses to CO2 and light. Abscisic Acid 165-168 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 86-94 33633834-4 2021 By using the ABA 8"-hydroxylase-deficient Arabidopsis thaliana double mutant cyp707a1 cyp707a3, which is unable to break down and instead accumulates high levels of ABA, we reveal the importance of the control of ABA concentration in mediating stomatal responses to CO2 and light. Abscisic Acid 165-168 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 86-94 33037128-6 2020 We further show that the transcripts of two genes key to ABA catabolism, CYP707A1 and CYP707A3, but not genes involved in ABA biosynthesis, were significantly reduced in ref6 mutants during seed development and germination. Abscisic Acid 57-60 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 86-94 33037128-8 2020 Genetic analysis demonstrated that the enhanced seed dormancy and ABA concentration in ref6 depended mainly on the reduced expression of CYP707A1 and CYP707A3. Abscisic Acid 66-69 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 150-158 31072449-7 2019 Real-time quantitative PCR (RT-qPCR) revealed that, in addition to known senescence-associated genes, genes encoding the ABA catabolic enzymes AtCYP707A3 and AtCYP707A4 were also significantly upregulated in OsMYB102- OX, leading to a significant decrease in ABA accumulation. Abscisic Acid 121-124 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 143-153 31072449-7 2019 Real-time quantitative PCR (RT-qPCR) revealed that, in addition to known senescence-associated genes, genes encoding the ABA catabolic enzymes AtCYP707A3 and AtCYP707A4 were also significantly upregulated in OsMYB102- OX, leading to a significant decrease in ABA accumulation. Abscisic Acid 259-262 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 143-153 22452852-2 2012 In Arabidopsis (Arabidopsis thaliana), two genes that inactivate abscisic acid, CYP707A1 and CYP707A3, are rapidly up-regulated upon rehydration. Abscisic Acid 65-78 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 93-101 30658512-7 2019 The analysis by quantitative real-time PCR (qRT-PCR) revealed that the expression of three stress-inducible genes (AtRAB18, AtERD10, and AtKIN1) were upregulated in the atpprt1 mutant and downregulated in AtPPRT1-overexpressing plants, while two ABA hydrolysis genes (AtCYP707A1 and AtCYP707A3) were downregulated in the atpprt1 mutant and upregulated in AtPPRT1-overexpressing plants in the presence of ABA. Abscisic Acid 246-249 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 283-293 30658512-7 2019 The analysis by quantitative real-time PCR (qRT-PCR) revealed that the expression of three stress-inducible genes (AtRAB18, AtERD10, and AtKIN1) were upregulated in the atpprt1 mutant and downregulated in AtPPRT1-overexpressing plants, while two ABA hydrolysis genes (AtCYP707A1 and AtCYP707A3) were downregulated in the atpprt1 mutant and upregulated in AtPPRT1-overexpressing plants in the presence of ABA. Abscisic Acid 404-407 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 283-293 19847111-4 2009 By analyzing cyp707a1, cyp707a2 and cyp707a3 mutants, we found that CYP707A2 plays a major role in ABA catabolism during the first stage of imbibition. Abscisic Acid 99-102 cytochrome P450, family 707, subfamily A, polypeptide 3 Arabidopsis thaliana 36-44