PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28716423-7 2017 Besides, genetic evidence indicated that NADK2 acted synergistically with OST1 and ABI1 during ABA-induced stomatal closure. Abscisic Acid 95-98 ribophorin I Homo sapiens 74-78 28438792-8 2017 Three ABA-responsive SnRK2s (SnRK2.2/SRK2D, SnRK2.3/SRK2I, and SnRK2.6/SRK2E/OST1) phosphorylated AKS1 in vitro, and the phosphorylation was eliminated by the triple mutation of SnRK2s in plants. Abscisic Acid 6-9 ribophorin I Homo sapiens 77-81 27856401-4 2016 VPS23A has epistatic relationship with PYR/PYL/RCAR-type ABA receptors and disruption of VPS23A enhanced the activity of key kinase OST1 in the ABA signaling pathway under ABA treatment. Abscisic Acid 57-60 ribophorin I Homo sapiens 132-136 27856401-4 2016 VPS23A has epistatic relationship with PYR/PYL/RCAR-type ABA receptors and disruption of VPS23A enhanced the activity of key kinase OST1 in the ABA signaling pathway under ABA treatment. Abscisic Acid 144-147 ribophorin I Homo sapiens 132-136 26724418-5 2016 ABA-induced OST1 expression and reactive oxygen species (ROS) production were also impaired in bak1. Abscisic Acid 0-3 ribophorin I Homo sapiens 12-16 26724418-7 2016 We demonstrated that BAK1 forms a complex with OST1 near the plasma membrane and that the BAK1/OST1 complex is increased in response to ABA in planta. Abscisic Acid 136-139 ribophorin I Homo sapiens 95-99 26724418-8 2016 Brassinolide, the most active BR, exerted a negative effect on ABA-induced formation of the BAK1/OST1 complex and OST1 expression. Abscisic Acid 63-66 ribophorin I Homo sapiens 97-101 26724418-8 2016 Brassinolide, the most active BR, exerted a negative effect on ABA-induced formation of the BAK1/OST1 complex and OST1 expression. Abscisic Acid 63-66 ribophorin I Homo sapiens 114-118 25005229-6 2014 The protein kinase OST1 (also known as SnRK2.6) is a key signaling player and central regulator in guard cells in response to ABA. Abscisic Acid 126-129 ribophorin I Homo sapiens 19-23 26024299-2 2015 In a recent study, we showed that endogenous NO negatively regulates abscisic acid (ABA) signaling in guard cells by inhibiting sucrose nonfermenting 1 (SNF1)-related protein kinase 2.6 (SnRK2.6)/open stomata 1(OST1) through S-nitrosylation. Abscisic Acid 69-82 ribophorin I Homo sapiens 211-215 26024299-2 2015 In a recent study, we showed that endogenous NO negatively regulates abscisic acid (ABA) signaling in guard cells by inhibiting sucrose nonfermenting 1 (SNF1)-related protein kinase 2.6 (SnRK2.6)/open stomata 1(OST1) through S-nitrosylation. Abscisic Acid 84-87 ribophorin I Homo sapiens 211-215 22935148-2 2013 We previously reported that SLAC1, an outward anion channel required for stomatal closure, was regulated via reversible protein phosphorylation events involving ABA signaling components, including protein phosphatase 2C members and a SnRK2-type kinase (OST1). Abscisic Acid 161-164 ribophorin I Homo sapiens 253-257 21575091-10 2011 The atabcg22 mutation further increased the water loss of srk2e/ost1 mutants, which were defective in ABA signalling in guard cells. Abscisic Acid 102-105 ribophorin I Homo sapiens 64-68 22126965-7 2011 OST1, the kinase CPK23, the calcium-dependent kinase CPK21, and the counteracting PP2Cs modulate the slow anion channel SLAC1, a pathway that contributes to stomatal responses to diverse stimuli, including ABA and carbon dioxide. Abscisic Acid 206-209 ribophorin I Homo sapiens 0-4 12468729-0 2002 Arabidopsis OST1 protein kinase mediates the regulation of stomatal aperture by abscisic acid and acts upstream of reactive oxygen species production. Abscisic Acid 80-93 ribophorin I Homo sapiens 12-16 20385816-3 2010 Open stomata 1 protein kinase (OST1) and ABI1 protein phosphatase (ABA insensitive 1) represent key components of calcium-independent ABA signaling. Abscisic Acid 134-137 ribophorin I Homo sapiens 31-35 20385816-13 2010 Thus the CPK and OST1 branch of ABA signal transduction in guard cells seem to converge on the level of SLAC1 under the control of the ABI1/ABA-receptor complex. Abscisic Acid 32-35 ribophorin I Homo sapiens 17-21 19955427-2 2009 Earlier genetic analyses uncovered a protein kinase (OST1) and several 2C-type phosphatases, as respective positive and negative regulators of ABA-induced stomatal closure. Abscisic Acid 143-146 ribophorin I Homo sapiens 53-57 19955427-5 2009 The results suggest that ABA signaling is mediated by a physical interaction chain consisting of several components, including a PP2C member, SnRK2-type kinase (OST1), and an ion channel, SLAC1, to regulate stomatal movements. Abscisic Acid 25-28 ribophorin I Homo sapiens 161-165 19924127-4 2009 Here we show that by combining the recently identified ABA receptor PYR1 with the type 2C protein phosphatase (PP2C) ABI1, the serine/threonine protein kinase SnRK2.6/OST1 and the transcription factor ABF2/AREB1, we can reconstitute ABA-triggered phosphorylation of the transcription factor in vitro. Abscisic Acid 55-58 ribophorin I Homo sapiens 159-171 19855047-7 2009 Our results provide evidence that PP2Cs are directly implicated in the ABA-dependent activation of OST1 and further suggest that the activation mechanism of AMPK/Snf1-related kinases through the inhibition of regulating PP2Cs is conserved from plants to human. Abscisic Acid 71-74 ribophorin I Homo sapiens 99-103 19302418-9 2009 The ABA-insensitive mutants ost1-2, abi2-1 and gca2 showed partial stomatal closure responses that correlate with [Ca2+]i-dependent ABA signaling. Abscisic Acid 4-7 ribophorin I Homo sapiens 28-34 19302418-9 2009 The ABA-insensitive mutants ost1-2, abi2-1 and gca2 showed partial stomatal closure responses that correlate with [Ca2+]i-dependent ABA signaling. Abscisic Acid 132-135 ribophorin I Homo sapiens 28-34 15064385-5 2004 Reciprocally, the stomata of ost1-2 are insensitive to ABA but are able to close in response to MJ to a lesser extent compared to wild-type plants. Abscisic Acid 55-58 ribophorin I Homo sapiens 29-33 12468729-3 2002 These recessive ost1 mutations disrupted ABA induction of stomatal closure as well as ABA inhibition of light-induced stomatal opening. Abscisic Acid 41-44 ribophorin I Homo sapiens 16-20 12468729-3 2002 These recessive ost1 mutations disrupted ABA induction of stomatal closure as well as ABA inhibition of light-induced stomatal opening. Abscisic Acid 86-89 ribophorin I Homo sapiens 16-20 12468729-4 2002 By contrast, the ost1 mutations did not affect stomatal regulation by light or CO(2), suggesting that OST1 is involved specifically in ABA signaling. Abscisic Acid 135-138 ribophorin I Homo sapiens 102-106 12468729-8 2002 ABA-induced ROS production was disrupted in ost1 guard cells, whereas applied H(2)O(2) or calcium elicited the same degree of stomatal closure in ost1 as in the wild type. Abscisic Acid 0-3 ribophorin I Homo sapiens 44-48 12468729-9 2002 These results suggest that OST1 acts in the interval between ABA perception and ROS production. Abscisic Acid 61-64 ribophorin I Homo sapiens 27-31 12468729-10 2002 The relative positions of ost1 and the other ABA-insensitive mutations in the ABA signaling network (abi1-1, abi2-1, and gca2) are discussed. Abscisic Acid 78-81 ribophorin I Homo sapiens 26-30 32463362-0 2020 FRET kinase sensor development reveals SnRK2/OST1 activation by ABA but not by MeJA and high CO2 during stomatal closure. Abscisic Acid 64-67 ribophorin I Homo sapiens 45-49 34021330-1 2021 OST1/SnRK2.6 is a critical component connecting abscisic acid (ABA) receptor complexes and downstream components, including anion channels and transcription factors. Abscisic Acid 48-61 ribophorin I Homo sapiens 0-4 34021330-1 2021 OST1/SnRK2.6 is a critical component connecting abscisic acid (ABA) receptor complexes and downstream components, including anion channels and transcription factors. Abscisic Acid 63-66 ribophorin I Homo sapiens 0-4 34021330-4 2021 We previously reported that BAK1 interacts with and phosphorylates OST1 to regulate ABA signaling. Abscisic Acid 84-87 ribophorin I Homo sapiens 67-71 34021330-7 2021 Phospho-mimetic transgenic plants containing quadruple changes in Y163, S164, S166, and S167 rescued ost1 mutant phenotypes, activating ABA signaling outputs. Abscisic Acid 136-139 ribophorin I Homo sapiens 101-105 34021330-9 2021 ABA induced tyrosine phosphorylation of Y182 in OST1; this event is catalytically important for OST1 activity in plants. Abscisic Acid 0-3 ribophorin I Homo sapiens 48-52 34021330-9 2021 ABA induced tyrosine phosphorylation of Y182 in OST1; this event is catalytically important for OST1 activity in plants. Abscisic Acid 0-3 ribophorin I Homo sapiens 96-100 34021330-11 2021 Our results indicate that phosphorylation cycles between OST1 and ABI1, which have dual specificity for tyrosine and serine/threonine, coordinately control ABA signaling. Abscisic Acid 156-159 ribophorin I Homo sapiens 57-61 32733520-10 2020 Our research further deciphered that OST1 which acts as an essential ABA-signaling component, also played a role in PIP1-induced stomatal closure. Abscisic Acid 69-72 ribophorin I Homo sapiens 37-41 31896774-5 2020 These M3Ks phosphorylate a specific SnRK2/OST1 site, which is indispensable for ABA-induced reactivation of PP2C-dephosphorylated SnRK2 kinases. Abscisic Acid 80-83 ribophorin I Homo sapiens 42-46 32391026-8 2020 Additionally, we also discuss the importance of the recently identified effector protein HOS15, which negatively regulate ABA-signaling through degradation of OST1. Abscisic Acid 122-125 ribophorin I Homo sapiens 159-163 30378140-6 2019 We further deciphered that two guard cell ABA-signalling components, OST1 and SLAC1, were responsible for CLE9-induced stomatal closure. Abscisic Acid 42-45 ribophorin I Homo sapiens 69-73 31491477-0 2019 Rheostatic Control of ABA Signaling through HOS15-Mediated OST1 Degradation. Abscisic Acid 22-25 ribophorin I Homo sapiens 59-63 31491477-3 2019 Here, we show that the desensitization of the ABA signal is achieved by the regulation of OST1 (SnRK2.6) protein stability via the E3-ubiquitin ligase HOS15. Abscisic Acid 46-49 ribophorin I Homo sapiens 90-94 31491477-4 2019 Upon ABA signal, HOS15-induced degradation of OST1 is inhibited and stabilized OST1 promotes the stress response. Abscisic Acid 5-8 ribophorin I Homo sapiens 46-50 31491477-4 2019 Upon ABA signal, HOS15-induced degradation of OST1 is inhibited and stabilized OST1 promotes the stress response. Abscisic Acid 5-8 ribophorin I Homo sapiens 79-83 31491477-5 2019 When the ABA signal terminates, protein phosphatases ABI1/2 promote rapid degradation of OST1 via HOS15. Abscisic Acid 9-12 ribophorin I Homo sapiens 89-93 31491477-6 2019 Notably, we found that even in the presence of ABA, OST1 levels are also depleted within hours of ABA signal onset. Abscisic Acid 47-50 ribophorin I Homo sapiens 52-56 31491477-6 2019 Notably, we found that even in the presence of ABA, OST1 levels are also depleted within hours of ABA signal onset. Abscisic Acid 98-101 ribophorin I Homo sapiens 52-56 31179540-1 2019 During drought, abscisic acid (ABA) induces closure of stomata via a signaling pathway that involves the calcium (Ca2+ )-independent protein kinase OST1, as well as Ca2+ -dependent protein kinases. Abscisic Acid 16-29 ribophorin I Homo sapiens 148-152 31179540-1 2019 During drought, abscisic acid (ABA) induces closure of stomata via a signaling pathway that involves the calcium (Ca2+ )-independent protein kinase OST1, as well as Ca2+ -dependent protein kinases. Abscisic Acid 31-34 ribophorin I Homo sapiens 148-152 31179540-2 2019 However, the interconnection between OST1 and Ca2+ signaling in ABA-induced stomatal closure has not been fully resolved. Abscisic Acid 64-67 ribophorin I Homo sapiens 37-41 31179540-7 2019 Loss of OST1 prevented ABA-induced stomatal closure and repressed Ca2+ signals, whereas elevation of the cytosolic Ca2+ concentration caused a rapid activation of SLAC1 and SLAH3 anion channels. Abscisic Acid 23-26 ribophorin I Homo sapiens 8-12 30282744-0 2018 Abscisic acid-independent stomatal CO2 signal transduction pathway and convergence of CO2 and ABA signaling downstream of OST1 kinase. Abscisic Acid 0-13 ribophorin I Homo sapiens 122-126 30282744-0 2018 Abscisic acid-independent stomatal CO2 signal transduction pathway and convergence of CO2 and ABA signaling downstream of OST1 kinase. Abscisic Acid 94-97 ribophorin I Homo sapiens 122-126 30282744-11 2018 The present study points to a model in which rapid CO2 signal transduction leading to stomatal closure occurs via an ABA-independent pathway downstream of OST1/SnRK2.6. Abscisic Acid 117-120 ribophorin I Homo sapiens 155-159 30282744-12 2018 Basal ABA signaling and OST1/SnRK2 activity are required to facilitate the stomatal response to elevated CO2 These findings provide insights into the interaction between CO2/ABA signal transduction in light of the continuing rise in atmospheric [CO2]. Abscisic Acid 174-177 ribophorin I Homo sapiens 24-28