PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20379410-5 2009 RESULTS: The cell viability in both the treatments at lower concentrations of SRB (1 and 10 muM) and MTT (1 muM) were found to be significantly higher than that observed at higher concentrations, while apoptosis in both the treatments at lower concentrations was observed to be significantly lower than at higher concentrations. monooxyethylene trimethylolpropane tristearate 101-104 latexin Homo sapiens 108-111 20379410-6 2009 Also, the cell viability of I + CUR at lower concentrations of SRB (1, 10 and 25 muM) and MTT (1 muM) were found to be significantly higher than the respective CUR, while apoptosis at higher concentrations (50, 75 and 100 muM), especially at 75 muM was significantly low. monooxyethylene trimethylolpropane tristearate 90-93 latexin Homo sapiens 97-100 20379410-6 2009 Also, the cell viability of I + CUR at lower concentrations of SRB (1, 10 and 25 muM) and MTT (1 muM) were found to be significantly higher than the respective CUR, while apoptosis at higher concentrations (50, 75 and 100 muM), especially at 75 muM was significantly low. monooxyethylene trimethylolpropane tristearate 90-93 latexin Homo sapiens 97-100 20379410-6 2009 Also, the cell viability of I + CUR at lower concentrations of SRB (1, 10 and 25 muM) and MTT (1 muM) were found to be significantly higher than the respective CUR, while apoptosis at higher concentrations (50, 75 and 100 muM), especially at 75 muM was significantly low. monooxyethylene trimethylolpropane tristearate 90-93 latexin Homo sapiens 97-100 32279036-10 2020 The IC50 values obtained in the MTT assay for the two cancer cells were found in the range of 3.4-10.8 muM. monooxyethylene trimethylolpropane tristearate 32-35 latexin Homo sapiens 103-106 31901813-5 2020 MTT assay indicated that MC-LR decreased the cellular viability by high concentration (>1 muM). monooxyethylene trimethylolpropane tristearate 0-3 latexin Homo sapiens 90-93 29410854-3 2018 In MTT assays nearly all the compounds displayed good cytotoxicity in the low muM range for several human tumour cell lines (A549, LOVO, SKOV3 and HepG2). monooxyethylene trimethylolpropane tristearate 3-6 latexin Homo sapiens 78-81 30853646-12 2019 MTT assay showed that compounds 1, 5-9, 12-13 and 15 had selective cytotoxic activities (IC50 27.20-163.03 muM) against tumor cells. monooxyethylene trimethylolpropane tristearate 0-3 latexin Homo sapiens 107-110 29579709-7 2018 Moreover, it showed cytotoxicity in K562 cells, in a concentration and time-dependent manner; IC50 values obtained were 399, 242 and 119 muM for trypan blue assay and 427, 259 and 50 muM for MTT method at 24, 48 or 72 h, respectively. monooxyethylene trimethylolpropane tristearate 191-194 latexin Homo sapiens 183-186 28278681-4 2017 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) test showed a dose-dependent viability reduction (r < -0.95; p < 0.01) (range 5-80 muM). monooxyethylene trimethylolpropane tristearate 62-65 latexin Homo sapiens 156-159 28490955-2 2017 MTT assay showed that hydrogen peroxide treatment at a concentration of 100 muM caused a significant (p < 0.005) reduction in the viability of MG63 cells. monooxyethylene trimethylolpropane tristearate 0-3 latexin Homo sapiens 76-79 28635256-6 2017 Accordingly, when a large amount of hydrogel formed in cells, the cell viability would be inhibited by ~90% by MTT assay at a concentration of 5.0 muM of hydrogel-loaded proteinosomes after 48 h incubation, which clearly proves the feasibility of the demonstrated method for killing cancer cells. monooxyethylene trimethylolpropane tristearate 111-114 latexin Homo sapiens 147-150 26055227-7 2016 Neurotoxicity of 100 muM MK-801, which reduced the cell viability, was diminished by 100 muM paliperidone using MTT and LDH assays (both p < 0.05). monooxyethylene trimethylolpropane tristearate 112-115 latexin Homo sapiens 89-92 30108751-6 2017 The MTT assay of DHQA showed a non-toxic effect against non-cancerous HEK-293T cells (EC50 = 820.00 muM), and potent inhibitory activity against cancerous Hela cells (EC50 = 138.17 muM). monooxyethylene trimethylolpropane tristearate 4-7 latexin Homo sapiens 100-103 30108751-6 2017 The MTT assay of DHQA showed a non-toxic effect against non-cancerous HEK-293T cells (EC50 = 820.00 muM), and potent inhibitory activity against cancerous Hela cells (EC50 = 138.17 muM). monooxyethylene trimethylolpropane tristearate 4-7 latexin Homo sapiens 181-184 27614406-4 2016 Six thiazolidinones showed significant effect of decreasing cell viability compared to standard drug TMZ at 100 muM in 72 h in C6 cell line by MTT assay. monooxyethylene trimethylolpropane tristearate 143-146 latexin Homo sapiens 112-115 28184324-6 2016 RESULTS: Through MTT assay, we found that the inhibitory concentration of 50% (IC50) values for VPA and CBZ were 2.5 mM and 5 muM, respectively in comparison to controls in terms of total concentration and times evaluated (P < 0.0001). monooxyethylene trimethylolpropane tristearate 17-20 latexin Homo sapiens 126-129 26999669-8 2016 MTT assay performed on ER(+) and ER(-) cell lines displayed selective inhibition of ER(+) cancer cell growth with IC50 = 14.3 muM which was comparable to tamoxifen. monooxyethylene trimethylolpropane tristearate 0-3 latexin Homo sapiens 126-129 26099171-4 2015 Drug toxicity of the nanoparticles was measured by MTT assay with different drug concentrations (0.01, 0.1, 0.5, 1 and 5 muM) at different incubation times (24, 48 and 72 h). monooxyethylene trimethylolpropane tristearate 51-54 latexin Homo sapiens 121-124 26099171-7 2015 Results obtained from MTT assay showed that 0.5 muM of free drug had 50 % toxicity on MCF-7 cells after 48-h incubation. monooxyethylene trimethylolpropane tristearate 22-25 latexin Homo sapiens 48-51 25075758-4 2014 MTT cell viability studies performed with breast cancer cell lines showed that half-maximal inhibitory concentration (IC50) values of nanoparticles for MCF7 and MDA-MB-231 were 44.7 muM and 24.8 muM, respectively. monooxyethylene trimethylolpropane tristearate 0-3 latexin Homo sapiens 195-198 25755702-3 2015 The data from MTT assay revealed a significant inhibitory effect on cell viability at 30 (87%) and 50 muM (74%) concentration of CHP in OVCAR-3 and OVCAR-420 cells, respectively after 72 h. Apoptosis analysis using annexin V/PI double staining followed by flow cytometry showed 59 and 52% binding to annexin V-FITC in OVCAR-3 and OVCAR-420 cells respectively. monooxyethylene trimethylolpropane tristearate 14-17 latexin Homo sapiens 102-105 25179425-8 2014 Correlation of MTT test and trypan blue staining revealed a decreased adherence of vital tumor cells at 250 muM TRD. monooxyethylene trimethylolpropane tristearate 15-18 latexin Homo sapiens 108-111 24930917-3 2014 MTT assay result showed that GB inhibited HepG2 cell proliferation in a dose- and time-dependent manner and 50% inhibiting concentration (IC50) of GB-induced cell death was 39.7 muM for a period of 48 h. GB-induced HepG2 apoptosis was confirmed by Hochest 33258 staining and PI staining. monooxyethylene trimethylolpropane tristearate 0-3 latexin Homo sapiens 178-181 22080437-5 2011 RESULTS: The 50% inhibitory concentration of asiaticoside for MCF-7 cells was determined with the MTT assay to be 40 muM. monooxyethylene trimethylolpropane tristearate 98-101 latexin Homo sapiens 117-120 23906970-3 2013 DEX in concentrations from 1 to 100 muM did not change LDH release but exposure to 10 muM and 100 muM DEX for 24, 48 and 72 h caused a significant reduction in cell viability and proliferation as confirmed by MTT reduction and BrdU ELISA assays, respectively. monooxyethylene trimethylolpropane tristearate 209-212 latexin Homo sapiens 86-89 23906970-3 2013 DEX in concentrations from 1 to 100 muM did not change LDH release but exposure to 10 muM and 100 muM DEX for 24, 48 and 72 h caused a significant reduction in cell viability and proliferation as confirmed by MTT reduction and BrdU ELISA assays, respectively. monooxyethylene trimethylolpropane tristearate 209-212 latexin Homo sapiens 86-89 22654634-3 2012 MTT spectrophotometry results showed that 20, 100, and 1000 muM aspirin doses have an inhibitory effect on growth. monooxyethylene trimethylolpropane tristearate 0-3 latexin Homo sapiens 60-63 24793880-3 2014 The series of compounds prepared displayed wide range of cytotoxicity in MTT assays (10-70 muM) across the cell lines tested. monooxyethylene trimethylolpropane tristearate 73-76 latexin Homo sapiens 91-94 23971075-4 2013 The results were correlated with parallel measurements from the MTT cytotoxicity assay, which yielded an IC50 value of 0.10 +- 0.03 muM. monooxyethylene trimethylolpropane tristearate 64-67 latexin Homo sapiens 132-135 23176403-8 2013 MTT assay showed the median IC50 (inhibitory concentrations) as follows: shikonin, sh-L1 and sh-L2 were 4.99+-0.23, 5.81+-0.57 and 7.17+-0.69 muM, respectively. monooxyethylene trimethylolpropane tristearate 0-3 latexin Homo sapiens 142-145 24377630-5 2013 RESULTS: MTT results showed that IC50 values for 24, 48 and 72h after treatment were 47, 44 and 43muM, respectively. monooxyethylene trimethylolpropane tristearate 9-12 latexin Homo sapiens 98-101 22659283-5 2012 Treatment of 1 nM letrozole in combination with 1 muM or 10 muM ZA resulted in an additive drug interaction on inhibition of cell viability, as measured by MTT assay. monooxyethylene trimethylolpropane tristearate 156-159 latexin Homo sapiens 50-53 22659283-5 2012 Treatment of 1 nM letrozole in combination with 1 muM or 10 muM ZA resulted in an additive drug interaction on inhibition of cell viability, as measured by MTT assay. monooxyethylene trimethylolpropane tristearate 156-159 latexin Homo sapiens 60-63 21547417-5 2011 However, cells exposed to 25 muM or higher concentrations of idebenone showed extensive trypan blue-positive staining and significant reduction in cell viability revealed by MTT assay indicating that most of the cells were no longer viable. monooxyethylene trimethylolpropane tristearate 174-177 latexin Homo sapiens 29-32 21093517-3 2011 Pretreatment with SCM198 (0.001, 0.01, 0.1, 1, and 10 muM) concentration-dependently increased the cell viability as measured in MTT and LDH leakage assays compared with 6-OHDA-injured cells. monooxyethylene trimethylolpropane tristearate 129-132 latexin Homo sapiens 54-57