PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22510844-9 2012 Surprisingly, changes to EGFR expression affected cell proliferation activities less significantly as determined by a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, an anchorage-independent growth assay, and cell cycle analysis. monooxyethylene trimethylolpropane tristearate 180-183 epidermal growth factor receptor Homo sapiens 25-29 18374401-5 2008 EGFR signaling was studied with Western blot analysis of EGFR, EGFR-p (phosphorylated), MAPK, and MAPK-p, and cellular proliferation examined by MTT assays. monooxyethylene trimethylolpropane tristearate 145-148 epidermal growth factor receptor Homo sapiens 0-4 22007484-9 2011 And the result of MTT assay showed rEG could specifically kill EGFR positive cells. monooxyethylene trimethylolpropane tristearate 18-21 epidermal growth factor receptor Homo sapiens 63-67 19631377-5 2009 IC(50) doses as determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium (MTT) assay showed the superior antiproliferative activity of EGFR-Rapa-NPs over unconjugated nanoparticles and native rapamycin due to higher cellular uptake on malignant breast cancer cells. monooxyethylene trimethylolpropane tristearate 85-88 epidermal growth factor receptor Homo sapiens 146-150 21479415-7 2008 MTT assay also showed that the in vitro antitumor activity of ZD6474 was dependent on EGFR tyrosine kinase inhibition at a higher dose. monooxyethylene trimethylolpropane tristearate 0-3 epidermal growth factor receptor Homo sapiens 86-90 8167053-4 1994 At 50 micrograms/ml, the EGFR, FGF, and PDGF MoAbs significantly decreased cell numbers by 31.0%, 31.2%, and 31.0%, respectively, when compared to control cultures in the MTT assay. monooxyethylene trimethylolpropane tristearate 171-174 epidermal growth factor receptor Homo sapiens 25-29 12011054-6 2002 The peptides effectively inhibited growth of two types of transformed cells overexpressing different erbB receptors, T6-17 and 32D, in standard MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) and cell viability assays. monooxyethylene trimethylolpropane tristearate 144-147 epidermal growth factor receptor Homo sapiens 101-105 11459199-5 2001 By MTT assay and compared with parental, intermediate-level EGFR-expressing ME180 cells, high EGFR-expressing ME180/TNF cells had a three- to fourfold increased sensitivity to cisplatin, camptothecin (CPT), and topotecan, and low EGFR-expressing ME180/Pt cells had a five- to ninefold reduced sensitivity to the same agents. monooxyethylene trimethylolpropane tristearate 3-6 epidermal growth factor receptor Homo sapiens 94-98 11459199-5 2001 By MTT assay and compared with parental, intermediate-level EGFR-expressing ME180 cells, high EGFR-expressing ME180/TNF cells had a three- to fourfold increased sensitivity to cisplatin, camptothecin (CPT), and topotecan, and low EGFR-expressing ME180/Pt cells had a five- to ninefold reduced sensitivity to the same agents. monooxyethylene trimethylolpropane tristearate 3-6 epidermal growth factor receptor Homo sapiens 94-98 10806840-1 1998 To investigate to what extent the growth of cultured subconjunctival fibroblasts was regulated by epidermal growth factor receptor (EGFR), we observed the expression of EGFR inhibited by interferon alpha-2b (IFN alpha-2b) and determined the growth of cultured subconjunctival fibroblasts by immunohistochemical and MTT methods. monooxyethylene trimethylolpropane tristearate 315-318 epidermal growth factor receptor Homo sapiens 169-173 35303882-4 2022 METHODS: EGFR-TKIs resistant NSCLC cells were established and confirmed by MTT assay. monooxyethylene trimethylolpropane tristearate 75-78 epidermal growth factor receptor Homo sapiens 9-13 31142691-10 2019 MTT results showed TPL had synergistic effect with three EGFR-TKIs at different concentrations on H1975 cells but not on H1299 cells. monooxyethylene trimethylolpropane tristearate 0-3 epidermal growth factor receptor Homo sapiens 57-61 29482638-11 2018 Additionally, 11 key pathways closely associated with hypoxia were identified, including focal adhesion, ErbB signaling, and proteoglycans in cancer, among which the ErbB signaling pathway was verified by RT-PCR, WB, and MTT assays. monooxyethylene trimethylolpropane tristearate 221-224 epidermal growth factor receptor Homo sapiens 166-170 30827261-8 2019 The cytotoxic effects of P38 alpha- siRNA and EGFR inhibitor were determined using MTT assay. monooxyethylene trimethylolpropane tristearate 83-86 epidermal growth factor receptor Homo sapiens 46-50 30827261-12 2019 Also, MTT assay showed that the cell viability after treatment with p38 alpha SiRNA, EGFR inhibitor and their combination was reduced to 51.02%, 48.9%, and 25.11%, respectively. monooxyethylene trimethylolpropane tristearate 6-9 epidermal growth factor receptor Homo sapiens 85-89 30136359-7 2018 Our study has demonstrated by MTT assay that combining BetA and an EGFR TKI increased the cytotoxicity against EGFR TKI-resistance lung cancer cells. monooxyethylene trimethylolpropane tristearate 30-33 epidermal growth factor receptor Homo sapiens 67-71 30136359-7 2018 Our study has demonstrated by MTT assay that combining BetA and an EGFR TKI increased the cytotoxicity against EGFR TKI-resistance lung cancer cells. monooxyethylene trimethylolpropane tristearate 30-33 epidermal growth factor receptor Homo sapiens 111-115 29522716-5 2018 MTT assay was first performed to detect the effect of inhibitors of c-ABL (imatinib) and EGFR (lapatinib) on FRBC cells. monooxyethylene trimethylolpropane tristearate 0-3 epidermal growth factor receptor Homo sapiens 89-93 28758931-7 2017 The effect of the EGFR blockade was assessed by treating the cells with gefitinib, and analyzed with the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and Western Blot (WB). monooxyethylene trimethylolpropane tristearate 167-170 epidermal growth factor receptor Homo sapiens 18-22 30223276-10 2018 RESULTS: We showed that the combination of ATL-1 and EGFR-TKI erlotinib further inhibited growth and induced cell arrest of the human lung cancer cells, determined by both MTT and flow cytometry assays. monooxyethylene trimethylolpropane tristearate 172-175 epidermal growth factor receptor Homo sapiens 53-57 28302075-15 2017 Nevertheless, there was a significant correlation between MTT (MTT1/MTT0) and eGFR (eGFR1/eGFR0) in case of Zn administration (rho = -0.49; 95%-CI: -0.78 to -0.03; p = 0.04). monooxyethylene trimethylolpropane tristearate 58-61 epidermal growth factor receptor Homo sapiens 78-82 28302075-18 2017 However, there was a significant negative correlation between MTT and eGFR in vivo in case of Zn administration, this could indicate a protective role of MTTs in a setting of reduced kidney function, which is possibly influenced by Zn. monooxyethylene trimethylolpropane tristearate 62-65 epidermal growth factor receptor Homo sapiens 70-74 28302075-18 2017 However, there was a significant negative correlation between MTT and eGFR in vivo in case of Zn administration, this could indicate a protective role of MTTs in a setting of reduced kidney function, which is possibly influenced by Zn. monooxyethylene trimethylolpropane tristearate 154-158 epidermal growth factor receptor Homo sapiens 70-74 27169285-3 2015 The MTT assay was carried out on three human cancer cell lines (A549, HepG2 and SMMC7721) with EGFR highly expressed. monooxyethylene trimethylolpropane tristearate 4-7 epidermal growth factor receptor Homo sapiens 95-99 25955731-6 2015 We demonstrated that combination of a MET inhibitor SU11274 with various EGFR inhibitors resulted in synergistic suppression of cell viability (in MTT assay) and cell survival (in colony formation assay) of MSL subtype TNBC cells. monooxyethylene trimethylolpropane tristearate 147-150 epidermal growth factor receptor Homo sapiens 73-77 23592411-4 2013 The growth of tongue cancer HSC-3 and lung cancer A549 cell lines treated with EGFR-TKI was assessed by MTT assay. monooxyethylene trimethylolpropane tristearate 104-107 epidermal growth factor receptor Homo sapiens 79-83 25776490-9 2015 MTT assay clearly showed the enhanced cell killing effect of CET-conjugated NP due to the selective delivery of GEM to the EGFR over expressing cancer cells. monooxyethylene trimethylolpropane tristearate 0-3 epidermal growth factor receptor Homo sapiens 123-127 25015231-9 2015 In addition, the MTT and soft-agar assay also identified that C23 or EGFR siRNAs could obviously affected cell growth (p=0.004) and invasiveness, as cell viability and colony formation decreased markedly. monooxyethylene trimethylolpropane tristearate 17-20 epidermal growth factor receptor Homo sapiens 69-73 24514079-4 2014 The consequences showed that resveratrol influenced the cellular state and reduced expression of EGFR on the cell surface, which were also interpreted by MTT assay and confocal microscopy assay. monooxyethylene trimethylolpropane tristearate 154-157 epidermal growth factor receptor Homo sapiens 97-101 24780295-7 2014 The effect of this interaction was tested with EGFR-ERCC1 knockdown in combination with gefitinib and NU7026 using the MTT and apoptosis assays. monooxyethylene trimethylolpropane tristearate 119-122 epidermal growth factor receptor Homo sapiens 47-51 24100279-5 2014 Determined by the MTT assay, the bispecific, enediyne-energized ER(Fv)-LDP-NGR-AE showed highly potent cytotoxicity to EGFR/CD13-overexpressed MCF-7 cells, with an IC50 value of 3.4x10 mol/l, whereas for the EGFR-overexpressed A431 cells, the IC50 value was 2.2x10 mol/l. monooxyethylene trimethylolpropane tristearate 18-21 epidermal growth factor receptor Homo sapiens 119-123