PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33574926-6 2021 The changes of cellular proliferation and migration induced by the interaction of Akt, RSK2 and H2A.X was determined by MTT, soft agar colony formation and cell migration experiments. monooxyethylene trimethylolpropane tristearate 120-123 AKT serine/threonine kinase 1 Homo sapiens 82-85 29725418-5 2018 Molecular mechanisms and the influences of different regulation the expression of AKT1 on HCC cell growth, proliferation were determined by western blotting, MTT and colony formation assays, cell cycle and apoptosis were investigated by flow cytometry. monooxyethylene trimethylolpropane tristearate 158-161 AKT serine/threonine kinase 1 Homo sapiens 82-86 32648127-2 2021 METHODS: The influences of noni juice on cell proliferation, apoptosis, invasion, migration and the activity of AKT/nuclear factor- kappa B (NF- kappa B) signaling pathway in A549 human lung cancer cells were detected by MTT, cell counting kit-8, colony formation, Annexin V/PI double labeling, transwell, scratch test and immunoblotting assay, respectively. monooxyethylene trimethylolpropane tristearate 221-224 AKT serine/threonine kinase 1 Homo sapiens 112-115 20017300-8 2009 It significantly inhibited the expression of AKT1, COX-2 and PIK3R1, and cell growth was inhibited over 70% as indicated by MTT assay and accompanied with G0/G1 phase arrest. monooxyethylene trimethylolpropane tristearate 124-127 AKT serine/threonine kinase 1 Homo sapiens 45-49 28229220-5 2017 We detected the effect of HepaCAM on the proliferation and viability of bladder cancer through AKT signaling by colony formation, the MTT assay and Western blotting. monooxyethylene trimethylolpropane tristearate 134-137 AKT serine/threonine kinase 1 Homo sapiens 95-98 27746366-7 2017 When blocking PTEN/Akt/FOXO1 signaling pathway, we demonstrated the effects of miR-222-mediated ADR resistance by MTT and apoptosis assays. monooxyethylene trimethylolpropane tristearate 114-117 AKT serine/threonine kinase 1 Homo sapiens 19-22 28096970-4 2016 MATERIALS AND METHODS: The role of Akt activation in TNF-alpha cytotoxicity was investigated by MTT cell viability assay following treatment of the cells with the chemical inhibitor of Akt activation with or without TNF-alpha treatment. monooxyethylene trimethylolpropane tristearate 96-99 AKT serine/threonine kinase 1 Homo sapiens 35-38 26163263-5 2015 In vitro MTT and transwell assays showed that Girdin and Akt are required for cell proliferation and migration during cellular quiescence. monooxyethylene trimethylolpropane tristearate 9-12 AKT serine/threonine kinase 1 Homo sapiens 57-60 22992944-7 2012 AKT overexpression (confirmed by western blotting) converted platinum-sensitive A2780 into platinum-resistant cells as shown by MTT assay. monooxyethylene trimethylolpropane tristearate 152-155 AKT serine/threonine kinase 1 Homo sapiens 0-3 22992944-8 2012 Importantly, platinum resistance of A2780cis cells could be reversed by downregulation of AKT, as demonstrated by MTT and clonogenicity assays and FACS analysis. monooxyethylene trimethylolpropane tristearate 126-129 AKT serine/threonine kinase 1 Homo sapiens 102-105 20412566-2 2010 METHODS: The activation of the PI3K/Akt and its effect on CNE-2Z cells in vivo and in vitro was investigated by MTT assay, flow cytometry, western blot, ELISA, terminal deoxyribonucleotide transferase-mediated nick-end labeling assays (TUNEL), and immunohistochemical analyses, using PI3K inhibitor, LY294002. monooxyethylene trimethylolpropane tristearate 112-115 AKT serine/threonine kinase 1 Homo sapiens 36-39 26998277-4 2016 The MTT assay demonstrated that sequential treatment of cisplatin, followed by the Akt inhibitor, MK-2206, caused a synergistic effect of proliferation inhibition, and the apoptosis assay by propidium iodide/fluorescein isothiocyanate staining also showed that combination treatment induced more apoptosis compared to the monotherapy groups. monooxyethylene trimethylolpropane tristearate 4-7 AKT serine/threonine kinase 1 Homo sapiens 83-86 23440492-4 2013 METHODS: Here, we investigate the ability of the PI3K/AKT inhibitor AEZS 126 to selectively target the triple-negative breast cancer (TNBC) cell proliferation and survival in vitro by MTT-assays and FACS-based analysis. monooxyethylene trimethylolpropane tristearate 184-187 AKT serine/threonine kinase 1 Homo sapiens 54-57 15900596-8 2005 When the chemotherapeutic sensibilities of these patients were studied in an MTT assay, it was found that the activated AKT was associated with increased resistance to multiple chemotherapeutic agents (5-fluorouracil, adriamycin, mitomycin C and cis-platinum). monooxyethylene trimethylolpropane tristearate 77-80 AKT serine/threonine kinase 1 Homo sapiens 120-123 17133272-5 2006 Also, we found that inhibition of Akt signalling by NFV enhanced the ability of docetaxel to inhibit the growth of NCI-H460 and -H520 cells, as measured by MTT assay. monooxyethylene trimethylolpropane tristearate 156-159 AKT serine/threonine kinase 1 Homo sapiens 34-37 12393269-0 2002 Amyloid beta-peptide alters the distribution of early endosomes and inhibits phosphorylation of Akt in the presence of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT). monooxyethylene trimethylolpropane tristearate 181-184 AKT serine/threonine kinase 1 Homo sapiens 96-99 12393269-6 2002 MTT induced phosphorylation of Akt and mitogen-activated protein kinase. monooxyethylene trimethylolpropane tristearate 0-3 AKT serine/threonine kinase 1 Homo sapiens 31-34 34077027-4 2021 METHODS: Cell viability was evaluated by MTT assay and its impact on mTOR/PI3K/AKT signalling pathway was estimated via western blot assay. monooxyethylene trimethylolpropane tristearate 41-44 AKT serine/threonine kinase 1 Homo sapiens 79-82