PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22812394-9 2013 The MTT data indicated that cytotoxicity of both Co(II) complexes and condensates is enhanced with increasing positive charges and bzim groups. monooxyethylene trimethylolpropane tristearate 4-7 mitochondrially encoded cytochrome c oxidase II Homo sapiens 49-55 22170686-9 2012 A decrease in COX-2 protein expression in COLO205-T cells by COX-2 siRNA transfection or enhanced GOS-induced cell death according to MTT assay and DNA integrity assay. monooxyethylene trimethylolpropane tristearate 134-137 mitochondrially encoded cytochrome c oxidase II Homo sapiens 14-19 23263802-5 2012 In the MTT assay in vitro, both compounds were identified as potent and selective COX-2 inhibitors. monooxyethylene trimethylolpropane tristearate 7-10 mitochondrially encoded cytochrome c oxidase II Homo sapiens 82-87 28916158-5 2017 Interestingly, the most potent compound in MTT assay, compound 12b, exhibited high inhibitory activity against COX-2 with selectivity index (COX-1/COX-2)>100. monooxyethylene trimethylolpropane tristearate 43-46 mitochondrially encoded cytochrome c oxidase II Homo sapiens 111-116 22147962-6 2011 Furthermore, COX-2 siRNA treatment inhibited cell proliferation (P < 0.01) and induced apoptosis in EC109 cells, as determined by an MTT assay and by flow cytometry, respectively. monooxyethylene trimethylolpropane tristearate 136-139 mitochondrially encoded cytochrome c oxidase II Homo sapiens 13-18 21835258-3 2012 Using the MTT method, we investigated the influence of the COX-2 selective inhibitor Celecoxib on the proliferation of KB/VCR oral cancer cell lines and analyzed the effect of Celecoxib on the regulation of P-glycoprotein (P-gp) expression and function. monooxyethylene trimethylolpropane tristearate 10-13 mitochondrially encoded cytochrome c oxidase II Homo sapiens 59-64 29191502-6 2018 Its ability to inhibit COX-2 in MCF-7 cell line was established and its cytotoxicity by MTT test was assessed. monooxyethylene trimethylolpropane tristearate 88-91 mitochondrially encoded cytochrome c oxidase II Homo sapiens 23-28 27217781-10 2016 MTT and invasion assays revealed that HER2 induced cell proliferation and invasion that were reversed by pretreatment with U0126 and COX-2 siRNA. monooxyethylene trimethylolpropane tristearate 0-3 mitochondrially encoded cytochrome c oxidase II Homo sapiens 133-138 25659740-4 2015 Furthermore, the Cu(II) and Co(II) complexes showed photocytotoxicity toward two selected tumor cell lines MCF-7 and A549 by 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide (MTT) method, and the Cu(II) complex exhibits higher photocytotoxicity than Co(II) complex against each of the selected cell lines, this result is identical with their DNA binding ability order. monooxyethylene trimethylolpropane tristearate 186-190 mitochondrially encoded cytochrome c oxidase II Homo sapiens 28-34 26163782-6 2015 The antitumor activity of Co(II) complex was tested by MTT assay. monooxyethylene trimethylolpropane tristearate 55-58 mitochondrially encoded cytochrome c oxidase II Homo sapiens 26-32