PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7363876-5 1980 Hypoxanthine can be oxidized further to uric acid by xanthine oxidase or to allantoin by xanthine oxidase and uricase. Allantoin 76-85 urate oxidase (pseudogene) Homo sapiens 110-117 2594778-1 1989 Urate oxidase, or uricase (EC 1.7.3.3), is a peroxisomal enzyme that catalyzes the oxidation of uric acid to allantoin in most mammals. Allantoin 109-118 urate oxidase (pseudogene) Homo sapiens 18-25 3192041-1 1988 Uricase is a peroxisomal liver enzyme that catalyzes the oxidation of uric acid to allantoin during purine catabolism. Allantoin 83-92 urate oxidase (pseudogene) Homo sapiens 0-7 29594655-10 2017 Uricase catalyzes the oxidation of uric acid (UA) to produce allantoin and H2O2 which etches the silver shell. Allantoin 61-70 urate oxidase (pseudogene) Homo sapiens 0-7 33601190-1 2021 INTRODUCTION: Pegloticase is a recombinant PEGylated uricase that converts relatively insoluble urate to highly water-soluble allantoin, which is readily excreted by the kidneys. Allantoin 126-135 urate oxidase (pseudogene) Homo sapiens 53-60 32720081-3 2020 Pegloticase, a recombinant uricase, converts uric acid to allantoin, a readily excreted molecule. Allantoin 58-67 urate oxidase (pseudogene) Homo sapiens 27-34 30890227-4 2019 Uricase is an efficient oxidase, which can oxidize uric acid to allantoin and hydrogen peroxide, to reduce the uric acid level. Allantoin 64-73 urate oxidase (pseudogene) Homo sapiens 0-7 36153-1 1979 Uricase (urate:oxygen oxidoreductase, EC 1.7.3.3) exposes a positional and steric specificity in the enzymic conversion of urate to allantoin. Allantoin 132-141 urate oxidase (pseudogene) Homo sapiens 0-7 36153-1 1979 Uricase (urate:oxygen oxidoreductase, EC 1.7.3.3) exposes a positional and steric specificity in the enzymic conversion of urate to allantoin. Allantoin 132-141 urate oxidase (pseudogene) Homo sapiens 9-36 488056-7 1979 The sensitivity of the method with xanthine as substrate can be doubled by the addition of uricase, which oxidizes uric acid to allantoin. Allantoin 128-137 urate oxidase (pseudogene) Homo sapiens 91-98 32452918-2 2020 In the evolutionary process, humans lost uricase, an enzyme that converts uric acid into allantoin, resulting in increased serum uric acid levels that may vary according to dietary ingestion, pathological conditions, and other factors. Allantoin 89-98 urate oxidase (pseudogene) Homo sapiens 41-48 30634585-2 2019 Urate oxidase (UOx) can oxidize uric acid to hydrogen peroxide and allantoin, which provides a good opportunity for electrochemical detection for UA. Allantoin 67-76 urate oxidase (pseudogene) Homo sapiens 0-13 30634585-2 2019 Urate oxidase (UOx) can oxidize uric acid to hydrogen peroxide and allantoin, which provides a good opportunity for electrochemical detection for UA. Allantoin 67-76 urate oxidase (pseudogene) Homo sapiens 15-18 27790013-3 2012 Pegloticase is a recombinant mammalian uricase conjugated to polyethylene glycol that catalyzes the oxidation of uric acid into allantoin, a more soluble end product. Allantoin 128-137 urate oxidase (pseudogene) Homo sapiens 39-46 26316329-6 2016 All other mammals possess the enzyme uricase that converts uric acid to allantoin that is easily eliminated through urine. Allantoin 72-81 urate oxidase (pseudogene) Homo sapiens 37-44 16375732-2 2005 Humans lack the enzyme uricase, which catalyzes the conversion of uric acid to allantoin. Allantoin 79-88 urate oxidase (pseudogene) Homo sapiens 23-30 22768707-1 2012 During millions years in all animals allantoine (oxidized by uricase uric acid) was catabolite of purines and ascorbic acid was an acceptor of active forms of oxygen. Allantoin 37-47 urate oxidase (pseudogene) Homo sapiens 61-68 17085964-2 2006 It is catabolized to allantoin by urate oxidase or uricase (E.C. Allantoin 21-30 urate oxidase (pseudogene) Homo sapiens 51-58 19081307-1 2009 Uric acid (UA) can be directly converted to allantoin enzymatically by uricase in most mammals except humans or by reaction with superoxide. Allantoin 44-53 urate oxidase (pseudogene) Homo sapiens 71-78 8290593-1 1994 Urate oxidase, or uricase (EC 1.7.3.3), is a purine metabolic enzyme that catalyzes the conversion of uric acid to allantoin in most mammals except humans and certain other primates. Allantoin 115-124 urate oxidase (pseudogene) Homo sapiens 18-25 15493112-2 2004 Uric acid is the last stage in purine degradation, because humans lack the enzyme uricase which converts uric acid into allantoin. Allantoin 120-129 urate oxidase (pseudogene) Homo sapiens 82-89 35495677-1 2022 Uricase catalyzes the conversion of uric acid into allantoin with concomitant reduction of molecular oxygen to hydrogen peroxide. Allantoin 51-60 urate oxidase (pseudogene) Homo sapiens 0-7