PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22690903-5	2012	Only lipopolysaccharide (LPS), poly(I:C), Pam3CSK4 and MALP-2 could induce the production of IL-6, IL-8 and MCP-1 by adipocytes.	Poly I	31-37	C-X-C motif chemokine ligand 8	Homo sapiens	99-103	
27468646-4	2016	CAM treatment led to a significant reduction in poly I:C- and RSV-mediated IL-8, CCL5, IFN-beta and -lambda production.	Poly I	48-54	C-X-C motif chemokine ligand 8	Homo sapiens	75-79	
26418032-6	2015	Inhibition of the TLR3, TLR/TIR-domain-containing adaptor-inducing interferon beta (TRIF), NF-kappaB, and IRF3 pathways decreased the polyI:C- and IL-17A/polyI:C-induced G-CSF and IL-8 mRNA expression.	Poly I	134-139	C-X-C motif chemokine ligand 8	Homo sapiens	180-184	
26418032-6	2015	Inhibition of the TLR3, TLR/TIR-domain-containing adaptor-inducing interferon beta (TRIF), NF-kappaB, and IRF3 pathways decreased the polyI:C- and IL-17A/polyI:C-induced G-CSF and IL-8 mRNA expression.	Poly I	154-159	C-X-C motif chemokine ligand 8	Homo sapiens	180-184	
25201625-11	2014	Furthermore, AhR-ligands alone at high concentrations induced a moderate CXCL8-response, without affecting CCL5, but suppressed both CXCL8 and CCL5-responses by Poly I:C. CONCLUSION: AhR and Arnt may differentially and independently regulate chemokine-responses induced by both inhaled pollutants and pulmonary infections.	Poly I	161-167	C-X-C motif chemokine ligand 8	Homo sapiens	133-138	
24237854-7	2013	RESULTS: We found that in ASMCs the TLR3 agonist poly I:C induced IL-8 release was reduced while induced IL-6 release by the TLR7/8 agonist imiquimod was further increased by the presence of piclamilast.	Poly I	49-55	C-X-C motif chemokine ligand 8	Homo sapiens	66-70	
21934447-8	2011	The poly (inosinic acid:cytidylic acid)-mediated lactic acid effect on IL-1beta and IL-8 release was abrogated when the lactic acid was neutralized or if acetic acid was substituted for lactic acid.	Poly I	4-23	C-X-C motif chemokine ligand 8	Homo sapiens	84-88	
22849850-10	2012	25-HC significantly potentiated IL-8 release in poly(I:C)-treated cells and the augmentation was inhibited by CAPE, BAY 11-7085, and SC-514.	Poly I	48-54	C-X-C motif chemokine ligand 8	Homo sapiens	32-36	
21964048-5	2011	The treatment of EPCs with TLR3 agonist Poly I:C up-regulated the expression of cytokines IL-1beta, IL-6, IL-8, TNF-alpha, IFN-alpha, and IFN-beta, indicating that EPCs expressed functional TLR3.	Poly I	40-46	C-X-C motif chemokine ligand 8	Homo sapiens	106-110	
21934447-6	2011	Poly (inosinic acid:cytidylic acid) by itself stimulated the release of IL-6 (305 pg/mL) and enhanced IL-8 production (2.8 ng/mL).	Poly I	0-19	C-X-C motif chemokine ligand 8	Homo sapiens	102-106	
21934447-7	2011	The combination of poly (inosinic acid:cytidylic acid) and lactic acid markedly increased IL-8 production (5.0 ng/mL) and induced the release of IL-1beta (96.2 pg/mL).	Poly I	19-38	C-X-C motif chemokine ligand 8	Homo sapiens	90-94	
16423036-3	2006	Stimulation of HCECs with the TLR3 agonist poly(I:C) induced the activation of nuclear factor (NF)-kappaB and production of the proinflammatory cytokine interleukin (IL)-6 and the chemokine IL-8.	Poly I	43-49	C-X-C motif chemokine ligand 8	Homo sapiens	190-194	
16911361-7	2006	RESULTS: Real-time PCR revealed that poly I : C significantly increased the expression of mRNAs for chemokines IP-10, RANTES, LARC, MIP-1alpha, IL-8, GRO-alpha and ENA-78 and cytokines IL-1beta, GM-CSF, IL-6 and the cell adhesion molecule ICAM-1 in both cell types.	Poly I	37-43	C-X-C motif chemokine ligand 8	Homo sapiens	144-148	
34666750-10	2021	LABA/GCS attenuation of Poly I:C or imiquimod-induced IL-6 and IL-8 were potentiated with ABCC4 and PDE4 inhibition, which was greater when ABCC4 and PDE4 inhibition was combined.	Poly I	24-30	C-X-C motif chemokine ligand 8	Homo sapiens	63-67	
15879132-3	2005	Accordingly, we observed that synthetic dsRNA, polyinosinic acid:cytidylic acid (poly(I:C)), potently induced gene remodeling in model intestinal epithelia with the specific pattern of expressed genes, including both classic proinflammatory genes (e.g., IL-8), as well as genes that are classically activated in virus-infected cells (e.g., IFN-responsive genes).	Poly I	47-64	C-X-C motif chemokine ligand 8	Homo sapiens	254-258	
32218789-13	2020	IC87114 decreased poly I:C-induced PD-L1 expression on PBECs and secretion of IL-6 and IL-8 into culture supernatants.	Poly I	18-24	C-X-C motif chemokine ligand 8	Homo sapiens	87-91