PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18541719-4 2008 Exposure to mf significantly down-regulated production of IFN-alpha, MIP-1alpha, IL-12p70, and IL-1alpha following activation with poly I:C, and of IL-12p40 following activation with poly I:C or LPS. Poly I 131-137 interleukin 1 alpha Homo sapiens 95-104 32898511-10 2020 IL-1beta is increased by LPS and Poly I:C after 1 day, but not by TNFalpha. Poly I 33-40 interleukin 1 alpha Homo sapiens 0-8 3262700-5 1988 When added 2 h or more before poly(I).poly(C), both forms of IL1 had a strong inhibitory effect on IFN-beta synthesis, as determined by antiviral assay of the IFN-beta protein or by quantitation of IFN-beta mRNA levels in Northern blot analysis. Poly I 30-37 interleukin 1 alpha Homo sapiens 61-64 34025139-8 2021 However, the treatment of RGE or SF in HaCaT cells in the presence of poly I:C, a toll-like receptor (TLR) 3 ligand, before UV exposure elicited the inhibition of the IL-1beta secretion. Poly I 70-76 interleukin 1 alpha Homo sapiens 167-175 3262700-6 1988 However, when IL1 was added simultaneously with poly(I).poly(C), or 2 h after poly(I).poly(C), IFN-beta synthesis was increased. Poly I 78-85 interleukin 1 alpha Homo sapiens 14-17 3262700-7 1988 The inhibitory action of IL1 on poly(I).poly(C)-induced IFN-beta synthesis was abolished in the presence of cycloheximide, suggesting that it is mediated indirectly by an IL1-induced product in the FS-4 cells. Poly I 32-39 interleukin 1 alpha Homo sapiens 25-28 3262700-7 1988 The inhibitory action of IL1 on poly(I).poly(C)-induced IFN-beta synthesis was abolished in the presence of cycloheximide, suggesting that it is mediated indirectly by an IL1-induced product in the FS-4 cells. Poly I 32-39 interleukin 1 alpha Homo sapiens 171-174 32978075-4 2020 In EE- and/or ES-healthy, IL-1beta and/or TNFalpha secretion after stimulation with LPS or poly I:C was significantly higher in cells with ATG13 knockdown compared with those with siRNA control (P < 0.03), whereas no significant difference was observed in either EE/ES-endo or EE/ES-hydro. Poly I 91-97 interleukin 1 alpha Homo sapiens 26-34