PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30449288-5	2019	We found that leucine increased slow MyHC protein level and decreased fast MyHC protein level, increased the levels of phospho-protein kinase B (Akt)/Akt and phospho-forkhead box 1 (FoxO1)/FoxO1 and decreased the FoxO1 protein level.	Leucine	14-21	myosin heavy chain 6	Homo sapiens	37-41	
33703997-5	2022	Our data showed that 4 mM leucine significantly increased protein expression levels of slow MyHC, Myoglobin, Troponin I-SS, AdipoQ, AdipoR1, phospho-AMPK (p-AMPK) and PGC-1alpha and mRNA expression levels of AMPKalpha2, PGC-1alpha, AdipoQ and AdipoR1, and significantly decreased fast MyHC protein expression.	Leucine	26-33	myosin heavy chain 6	Homo sapiens	92-96	
33703997-7	2022	However, knockdown of AdipoR1 expression by AdipoR1-siRNA abolished leucine-induced upregulation of protein expressions of slow MyHC, AdipoR1, p-AMPK, PGC-1alpha and NRF1, mRNA expressions of MyHC I, MyHC IIa, AdipoR1, AMPKalpha2 and PGC-1alpha, ATP5G, TFAM and NRF1, and mtDNA level, as well as downregulation of protein expression of fast MyHC and mRNA expression of MyHC IIb.	Leucine	68-75	myosin heavy chain 6	Homo sapiens	128-132	
33703997-7	2022	However, knockdown of AdipoR1 expression by AdipoR1-siRNA abolished leucine-induced upregulation of protein expressions of slow MyHC, AdipoR1, p-AMPK, PGC-1alpha and NRF1, mRNA expressions of MyHC I, MyHC IIa, AdipoR1, AMPKalpha2 and PGC-1alpha, ATP5G, TFAM and NRF1, and mtDNA level, as well as downregulation of protein expression of fast MyHC and mRNA expression of MyHC IIb.	Leucine	68-75	myosin heavy chain 6	Homo sapiens	192-196	
30449288-9	2019	Moreover, over-expression of miR-27a repressed transformation from fast MyHC to slow MyHC caused by leucine, suggesting that miR-27a is interdicted by leucine and then contributes to porcine muscle fibre type transformation.	Leucine	100-107	myosin heavy chain 6	Homo sapiens	72-76	
30449288-9	2019	Moreover, over-expression of miR-27a repressed transformation from fast MyHC to slow MyHC caused by leucine, suggesting that miR-27a is interdicted by leucine and then contributes to porcine muscle fibre type transformation.	Leucine	151-158	myosin heavy chain 6	Homo sapiens	72-76	
30449288-10	2019	Our finding provided the first evidence that leucine promotes porcine myofibre type transformation from fast MyHC to slow MyHC via the Akt/FoxO1 signalling pathway and miR-27a.	Leucine	45-52	myosin heavy chain 6	Homo sapiens	109-113	
25268835-5	2014	Leucine also reduced neonatal myosin heavy chain (MyHC-n) (p < 0.05), increased adult MyHC-II expression (p < 0.05) and prevented the decrease in maximum tetanic strength in regenerating TA muscles (p < 0.05).	Leucine	0-7	myosin heavy chain 6	Homo sapiens	50-54	
25268835-5	2014	Leucine also reduced neonatal myosin heavy chain (MyHC-n) (p < 0.05), increased adult MyHC-II expression (p < 0.05) and prevented the decrease in maximum tetanic strength in regenerating TA muscles (p < 0.05).	Leucine	0-7	myosin heavy chain 6	Homo sapiens	89-93