PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23404499-3 2013 The leucine-facilitated insulin-induced phosphorylation of Akt at residue 473 was not affected by knocking down the key component of mTORC1 or -2 complexes but was blocked by inhibition of c-Src (PP2), PI3K (LY294002), Galphai protein (pertussis toxin or siRNA against Galphai1 gene, or beta-arrestin 2 (siRNA)). Leucine 4-11 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 189-194 18039857-5 2008 c-Src with a C-terminal Leu/Ala mutation in GENL (Src-A) promoted the activation and translocation of cortactin and focal adhesion kinase and increased the motility and persistence of cell migration on the basement membrane. Leucine 24-27 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 0-5 18039857-7 2008 We ascribe the regulatory function of C-terminal Leu to the role of GENL in modulating c-Src activity downstream of cell matrix adhesion. Leucine 49-52 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 87-92 17491594-3 2007 The C-terminal residue Leu of c-Src is essential for binding to a PDZ domain. Leucine 23-26 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 30-35 9192902-3 1997 Here we report that a short sequence motif LXXLL (where L is leucine and X is any amino acid) present in RIP-140, SRC-1 and CBP is necessary and sufficient to mediate the binding of these proteins to liganded nuclear receptors. Leucine 61-68 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 114-119 1691439-3 1990 This neuronal exon (the NII exon) of C-SRC was isolated from human adult and fetal brain-derived cDNAs and contains 33 nucleotides capable of encoding 11 amino acids (Gln-Thr-Trp-Phe-Thr-Phe-Arg-Trp-Leu-Gln-Arg). Leucine 199-202 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 37-42 10426955-8 1999 Our analyses lead us to suggest that the Leu 255-pocket interaction is a critical component of the intramolecular inhibition mechanism of Src family kinases. Leucine 41-44 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 138-141