PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1306524-9	1992	Single amino acid substitutions replacing Arg 201 with either Cys or His or Gln 227 with either Arg or Leu cause constitutive activation of adenylyl cyclase by inhibiting GTPase (gsp oncogene).	Leucine	103-106	GSM1	Homo sapiens	179-182	
21357415-6	2011	The aggressive pathogenic PS1 L166P mutation was one of the few pathogenic mutations that resisted GSM-1, and Leu-166 was identified as a critical residue with respect to the Abeta(42)-lowering response of GSM-1.	Leucine	110-113	GSM1	Homo sapiens	206-211