PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1306524-9 1992 Single amino acid substitutions replacing Arg 201 with either Cys or His or Gln 227 with either Arg or Leu cause constitutive activation of adenylyl cyclase by inhibiting GTPase (gsp oncogene). Leucine 103-106 GSM1 Homo sapiens 179-182 21357415-6 2011 The aggressive pathogenic PS1 L166P mutation was one of the few pathogenic mutations that resisted GSM-1, and Leu-166 was identified as a critical residue with respect to the Abeta(42)-lowering response of GSM-1. Leucine 110-113 GSM1 Homo sapiens 206-211