PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21282353-0 2011 Radiosensitization of head and neck squamous cell carcinoma by a SMAC-mimetic compound, SM-164, requires activation of caspases. smac 65-69 caspase 8 Homo sapiens 119-127 20019748-6 2010 Significantly, sensitisation towards poly I:C-dependent caspase-8 activation and apoptosis in melanoma cells was also achieved by the synthetic Smac mimetic/inhibitor of apoptosis protein (IAP) antagonist, LBW242, or by specific downregulation of cIAP1 by siRNA. smac 144-148 caspase 8 Homo sapiens 56-65