PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16437149-0 2006 The GATA site-dependent hemogen promoter is transcriptionally regulated by GATA1 in hematopoietic and leukemia cells. gata 4-8 GATA binding protein 1 Homo sapiens 75-80 24021675-8 2013 The 3.2-kb sequences interspaced between the Gata1 hematopoietic enhancer and the double GATA-motif were able to recruit DNA methyltransferase 1, thereby exerting a cis-repressive function in the HSC-like cell line. gata 89-93 GATA binding protein 1 Homo sapiens 45-50 18443038-4 2008 DNA-protein binding assays showed that the GATA motif of interest is capable of binding GATA-1 transcription factor in vitro and in vivo. gata 43-47 GATA binding protein 1 Homo sapiens 88-94 22865859-6 2012 These two GATA motifs possess the capacity to bind GATA1 and GATA2 in EMSA. gata 10-14 GATA binding protein 1 Homo sapiens 51-56 21279818-7 2011 GATA2 is expressed earlier in erythropoiesis than GATA1, and prior GATA2 binding may afford GATA1 access to GATA motifs through epigenetic remodeling and thus facilitate target gene expression. gata 0-4 GATA binding protein 1 Homo sapiens 92-97 1827068-5 1991 hGATA-3 contains a zinc finger domain that is highly related to the DNA-binding domain of the erythroid-specific transcription factor, GATA-1, and binds to a region of T alpha 3 that contains a consensus GATA binding site (AGATAG). gata 1-5 GATA binding protein 1 Homo sapiens 135-141 12724402-7 2003 Quantitative electrophoretic mobility shift assays using oligonucleotides derived from the GPIX promoter containing Ets and GATA binding motifs reveal that Fli-1 and GATA-1 exhibit cooperative DNA binding in which the binding of GATA-1 to DNA is increased approximately 26-fold in the presence of Fli-1 (from 4.2 to 0.16 nM), providing a mechanism for the observed transcriptional synergy. gata 124-128 GATA binding protein 1 Homo sapiens 166-172 12724402-7 2003 Quantitative electrophoretic mobility shift assays using oligonucleotides derived from the GPIX promoter containing Ets and GATA binding motifs reveal that Fli-1 and GATA-1 exhibit cooperative DNA binding in which the binding of GATA-1 to DNA is increased approximately 26-fold in the presence of Fli-1 (from 4.2 to 0.16 nM), providing a mechanism for the observed transcriptional synergy. gata 124-128 GATA binding protein 1 Homo sapiens 229-235 12200364-9 2002 Compared with wild-type GATA-1, Arg216Gln GATA-1 shows comparable affinity to single GATA sites but decreased affinity to palindromic sites. gata 24-28 GATA binding protein 1 Homo sapiens 42-48 10862620-5 2000 The GATA motifs bound GATA-1 and mutagenesis analysis revealed that the proximal one is critical for the enhancing activity. gata 4-8 GATA binding protein 1 Homo sapiens 22-28 9642238-10 1998 The GATA motif bound GATA-1 in vitro. gata 4-8 GATA binding protein 1 Homo sapiens 21-27 8703016-9 1996 The mutation changes a GATA consensus binding site, disrupts GATA-1 binding to the mutated site, and decreases promoter activity by 84%. gata 23-27 GATA binding protein 1 Homo sapiens 61-67 7760810-7 1995 ER-mediated repression of GATA-1 activity occurs on an artificial promoter containing a single GATA-binding site, as well as in the context of an intact promoter which is normally regulated by GATA-1. gata 26-30 GATA binding protein 1 Homo sapiens 193-199 1396592-3 1992 We used gel shift and transfection assays to demonstrate that the GATA motif in the SCL promoter binds GATA-1 (and GATA-2), and also mediates transcriptional transactivation. gata 66-70 GATA binding protein 1 Homo sapiens 103-109 2388628-11 1990 We conclude that a nuclear factor with binding specificity for a GATA motif similar to that of the transcriptional activator GF-1 is necessary for the efficient and cell-specific expression of the human PPET-1 gene. gata 65-69 GATA binding protein 1 Homo sapiens 125-129