PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2719954-5	1989	Pancreatic carboxypeptidase A (CP-A) hydrolyzed MTX-Ala and, at a much slower rate, MTX-Asp and MTX-Arg.	methotrexate-alpha-alanine	48-55	carboxypeptidase A1, pancreatic	Mus musculus	31-35	
2719954-9	1989	MTX-Ala was much less toxic than MTX (ID50 values of 2.0 X 10(-6) M and 2.4 x 10(-8) M, respectively), but in the presence of CP-A the ID50 of the peptide improved to 8.5 X 10(-8) M. Similar results were obtained with MTX-Asp/CP-A and MTX-Ala/CP-B combinations.	methotrexate-alpha-alanine	0-7	carboxypeptidase A1, pancreatic	Mus musculus	126-130	
2719954-9	1989	MTX-Ala was much less toxic than MTX (ID50 values of 2.0 X 10(-6) M and 2.4 x 10(-8) M, respectively), but in the presence of CP-A the ID50 of the peptide improved to 8.5 X 10(-8) M. Similar results were obtained with MTX-Asp/CP-A and MTX-Ala/CP-B combinations.	methotrexate-alpha-alanine	0-7	carboxypeptidase A1, pancreatic	Mus musculus	226-230