PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10901311-5 2000 METHODS: We previously isolated a clonal cell line (MOS/ADR1) to study acquired resistance in osteosarcoma by exposure of parental murine osteosarcoma cells (MOS) to doxorubicin. Doxorubicin 166-177 Moloney sarcoma oncogene Mus musculus 52-55 11299755-9 2001 These findings indicated that PEMFs reversed the DOX resistance of the MOS/ADR1 cells by inhibiting P-gp function. Doxorubicin 49-52 Moloney sarcoma oncogene Mus musculus 71-74 10901311-7 2000 RESULTS: The MOS/ADR1 and MOS/IR1 cells were sevenfold and fivefold more resistant to doxorubicin than the parental murine osteosarcoma cells. Doxorubicin 86-97 Moloney sarcoma oncogene Mus musculus 13-16 10901311-7 2000 RESULTS: The MOS/ADR1 and MOS/IR1 cells were sevenfold and fivefold more resistant to doxorubicin than the parental murine osteosarcoma cells. Doxorubicin 86-97 Moloney sarcoma oncogene Mus musculus 26-29 10901311-13 2000 The addition of a P-glycoprotein antagonist, verapamil, or the depletion of cellular adenosine triphosphate resulted in a marked increase in the accumulation of doxorubicin in the MOS/ADR1 cells (p < 0.05) but not in the MOS/ IR1 cells. Doxorubicin 161-172 Moloney sarcoma oncogene Mus musculus 180-183 10901311-13 2000 The addition of a P-glycoprotein antagonist, verapamil, or the depletion of cellular adenosine triphosphate resulted in a marked increase in the accumulation of doxorubicin in the MOS/ADR1 cells (p < 0.05) but not in the MOS/ IR1 cells. Doxorubicin 161-172 Moloney sarcoma oncogene Mus musculus 224-227 10901311-5 2000 METHODS: We previously isolated a clonal cell line (MOS/ADR1) to study acquired resistance in osteosarcoma by exposure of parental murine osteosarcoma cells (MOS) to doxorubicin. Doxorubicin 166-177 Moloney sarcoma oncogene Mus musculus 158-161 10901311-14 2000 The MOS/ADR1 cells were found to exhibit cross-resistance only to substrates for P-glycoprotein (such as doxorubicin, vincristine, and etoposide), whereas the MOS/IR1 cells were resistant to all of the drugs studied (including cisplatin and methotrexate). Doxorubicin 105-116 Moloney sarcoma oncogene Mus musculus 4-7 8613443-5 1996 The MOS/ADR1 and MOS/ADR2 cells were sevenfold and eighteenfold more resistant to Adriamycin than the cells from the parent line. Doxorubicin 82-92 Moloney sarcoma oncogene Mus musculus 4-7 8613443-5 1996 The MOS/ADR1 and MOS/ADR2 cells were sevenfold and eighteenfold more resistant to Adriamycin than the cells from the parent line. Doxorubicin 82-92 Moloney sarcoma oncogene Mus musculus 17-20