PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19036079-5 2009 This was more notable in children who received idarubicin, fludarabine, ara-C, and granulocyte colony-stimulating factor (IDA-FLAG; ara-C = 7590 mg/m2) (5-year TRM 24 +/- 21% CC vs. 6 +/- 6% AA, 6 +/- 7% AC, P = 0.07) as consolidation therapy compared to idarubicin, dexamethasone, cytarabine, thioguanine, etoposide and daunomycin (IDA-DCTER; ara-C = 800 mg/m2) (5-year TRM 15 +/- 20% CC vs. 8 +/- 6% AA, 4 +/- 6% AC; P = 0.29). Daunorubicin 321-331 colony stimulating factor 3 Homo sapiens 83-120 15380050-7 2004 The effect of G-CSF, GM-CSF, IL3 and M-CSF on daunorubicin mediated cytotoxicity in K562 cells was measured using the MTT assay. Daunorubicin 46-58 colony stimulating factor 3 Homo sapiens 14-19 8599980-9 1996 G-CSF significantly enhanced the cytotoxic effect of daunorubicin, mitoxantrone, etoposide and Ara-C by 20-40%, which GM-CSF and IL-3 showed a significantly increased toxicity for Ara-C only. Daunorubicin 53-65 colony stimulating factor 3 Homo sapiens 0-5 18493867-0 2008 Granulocyte colony stimulating factor increases drug resistance of leukaemic blast cells to daunorubicin. Daunorubicin 92-104 colony stimulating factor 3 Homo sapiens 0-37 18493867-6 2008 In this study we investigated how G-CSF might influence the sensitivity of leukemic cells to daunorubicin induced cell death using MTT assay, flow cytometry and Western blot analysis. Daunorubicin 93-105 colony stimulating factor 3 Homo sapiens 34-39 18493867-7 2008 After pretreatment of KG-1 leukaemic cells with G-CSF a moderate increase in the resistance of these cells to daunorubicin could be observed. Daunorubicin 110-122 colony stimulating factor 3 Homo sapiens 48-53 18493867-9 2008 In addition, adjuvant treatment of AML patients with G-CSF in order to prevent neutropenia, or its use in priming regimens might result resistance to daunorubicin. Daunorubicin 150-162 colony stimulating factor 3 Homo sapiens 53-58 9685063-11 1998 We conclude that G-CSF and IL-3 augment the effect of daunorubicin on normal hematopoietic progenitor cells. Daunorubicin 54-66 colony stimulating factor 3 Homo sapiens 17-22 1699657-5 1990 According to in vitro cytotoxic assay, the sensitivity of G-CSF-stimulated cells to intercalating (daunorubicin) and nonintercalating (etoposide) topo II-targeting drugs increased significantly, whereas no enhancement of sensitivity was observed with an alkylating agent (4-hydroperoxycyclophosphamide). Daunorubicin 99-111 colony stimulating factor 3 Homo sapiens 58-63