PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27994664-10 2016 Interestingly, expression of NPM1mA could upregulate Bax and downregulate Bcl-2 at mRNA and protein levels in THP-1 cells when treated with DNR or Ara-C. Daunorubicin 140-143 nucleophosmin 1 Homo sapiens 29-33 26755712-6 2016 Patients with FLT3-ITD (24%),DNMT3A(24%), and NPM1(26%) mutant AML all benefited from HD daunorubicin (HR, 0.61,P= .009; HR, 0.62,P= .02; and HR, 0.50,P= .002; respectively). Daunorubicin 89-101 nucleophosmin 1 Homo sapiens 46-50 25795919-8 2015 Strikingly, NPM1 mutant downregulation by ATO/ATRA was shown to potentiate response to the anthracyclin daunorubicin. Daunorubicin 104-116 nucleophosmin 1 Homo sapiens 12-16 2200756-6 1990 Relocation of protein B23 in nucleoli was observed in cells of stationary growth after treatment with adriamycin or daunomycin at their subtoxic concentrations (10(-10) M). Daunorubicin 116-126 nucleophosmin 1 Homo sapiens 22-25 22417203-9 2012 High-dose daunorubicin, as compared with standard-dose daunorubicin, improved the rate of survival among patients with DNMT3A or NPM1 mutations or MLL translocations (P=0.001) but not among patients with wild-type DNMT3A, NPM1, and MLL (P=0.67). Daunorubicin 10-22 nucleophosmin 1 Homo sapiens 129-133 22417203-9 2012 High-dose daunorubicin, as compared with standard-dose daunorubicin, improved the rate of survival among patients with DNMT3A or NPM1 mutations or MLL translocations (P=0.001) but not among patients with wild-type DNMT3A, NPM1, and MLL (P=0.67). Daunorubicin 10-22 nucleophosmin 1 Homo sapiens 222-226 10527882-6 1999 GFP-NPM(N) dissociates from nucleoli after treatments with daunomycin, actinomycin D, camptothecin, and toyocamycin. Daunorubicin 59-69 nucleophosmin 1 Homo sapiens 4-7 8620441-6 1996 The effect of two classes of anthracycline (daunomycin and aclacinomycin A) and different types of intercalators (daunomycin and actinomycin D) had additive effects on induction of NPM-translocation. Daunorubicin 44-54 nucleophosmin 1 Homo sapiens 181-184 8620441-6 1996 The effect of two classes of anthracycline (daunomycin and aclacinomycin A) and different types of intercalators (daunomycin and actinomycin D) had additive effects on induction of NPM-translocation. Daunorubicin 114-124 nucleophosmin 1 Homo sapiens 181-184 10230770-0 1999 A study of correlation between NPM-translocation and apoptosis in cells induced by daunomycin. Daunorubicin 83-93 nucleophosmin 1 Homo sapiens 31-34 10230770-13 1999 Taken together, these results indicate that NPM-translocation correlates with apoptosis induced by daunomycin. Daunorubicin 99-109 nucleophosmin 1 Homo sapiens 44-47 2200756-7 1990 Adriamycin and daunomycin, at their toxic concentrations (greater than 5.0 x 10(-7) M), on the other hand, inhibited cell growth and induced B23 translocation from nucleoli to nucleoplasm in growing cells. Daunorubicin 15-25 nucleophosmin 1 Homo sapiens 141-144 2910487-0 1989 Cyclosporin A and verapamil enhancement of daunorubicin-produced nucleolar protein B23 translocation in daunorubicin-resistant and -sensitive human and murine tumor cells. Daunorubicin 43-55 nucleophosmin 1 Homo sapiens 83-86 2910487-0 1989 Cyclosporin A and verapamil enhancement of daunorubicin-produced nucleolar protein B23 translocation in daunorubicin-resistant and -sensitive human and murine tumor cells. Daunorubicin 104-116 nucleophosmin 1 Homo sapiens 83-86