PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12410571-0 2002 Resistance of bcr-abl-positive acute lymphoblastic leukemia to daunorubicin is not mediated by mdr1 gene expression. Daunorubicin 63-75 ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens 14-21 12410571-9 2002 The median LD(50) of daunorubicin (concentration lethal to 50% of the leukemic blasts) differed significantly between bcr-abl-positive and -negative patients (P = 0.018). Daunorubicin 21-33 ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens 118-125 12410571-10 2002 This in vitro study suggests that bcr-abl-positive ALL is relatively resistant to daunorubicin, but this resistance is not mediated through mdr1 gene expression. Daunorubicin 82-94 ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens 34-41