PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29870138-10	2018	Daunorubicin, mycophenolic acid, and pyrvinium could potentially target the hub gene CHEK1 directly.	Daunorubicin	0-12	checkpoint kinase 1	Homo sapiens	85-90	
26727128-6	2016	Caffeine, which is an inhibitor of ataxia telangiectasia mutated protein (ATM) and ataxia telangiectasia mutated and Rad3-related protein (ATR), and the Chk1 inhibitor inhibited the TER increases induced by daunorubicin and rebeccamycin, whereas a Chk2 inhibitor did not.	Daunorubicin	207-219	checkpoint kinase 1	Homo sapiens	153-157	
28030834-7	2017	We found that inhibition of both HDAC1 and HDAC2 was necessary to decrease the expression of BRCA1, CHK1, and RAD51, enhance cytarabine- or daunorubicin-induced DNA damage and apoptosis, and abrogate cytarabine- or daunorubicin-induced cell cycle checkpoint activation in AML cells.	Daunorubicin	215-227	checkpoint kinase 1	Homo sapiens	100-104	
26727128-9	2016	Our results suggest that Chk1 activation by daunorubicin and rebeccamycin induced claudin-5 expression and enhanced TJ barrier function in Caco-2 cell monolayer, which suggests a link between DNA damage and TJ integrity in the human intestine.	Daunorubicin	44-56	checkpoint kinase 1	Homo sapiens	25-29	
25697484-8	2015	Both Aa and Ap attenuated daunorubicin-stimulated activation of the DNA damage response (DDR) as reflected on the levels of gammaH2AX, p-Kap-1 and p-Chk-1.	Daunorubicin	26-38	checkpoint kinase 1	Homo sapiens	149-154