PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10617675-8	2000	Further comparison revealed that although MDR1 easily impaired uptake of vincristine, daunomycin, paclitaxel, and digoxin, SPGP had no effect on uptake of these drugs.	Daunorubicin	86-96	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	42-46	
11369136-0	2001	Induction of apoptosis in MDR1 expressing cells by daunorubicin with combinations of suboptimal concentrations of P-glycoprotein modulators.	Daunorubicin	51-63	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	26-30	
9820176-10	1998	In contrast, induction seemed to determine resistance in EHR2 cells in vitro exposed to daunorubicin 10(-8) M. The revertant EHR2/0.8/R was treated in vivo with daunorubicin for 24 h. After treatment, P-glycoprotein increased in EHR2/0.8/R (sevenfold) and the cell line developed resistance to daunorubicin (12-fold), suggesting that in EHR2/0.8/R the mdr1 gene was activated by induction.	Daunorubicin	161-173	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	352-356	
9820176-10	1998	In contrast, induction seemed to determine resistance in EHR2 cells in vitro exposed to daunorubicin 10(-8) M. The revertant EHR2/0.8/R was treated in vivo with daunorubicin for 24 h. After treatment, P-glycoprotein increased in EHR2/0.8/R (sevenfold) and the cell line developed resistance to daunorubicin (12-fold), suggesting that in EHR2/0.8/R the mdr1 gene was activated by induction.	Daunorubicin	161-173	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	352-356	
2567301-2	1989	NIH3T3 cells expressing a transfected MDR1 gene (NIH3T3-MDR) were treated with vinblastine or daunomycin.	Daunorubicin	94-104	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	38-42	
8650203-4	1996	Expression of mouse Mdr1 in the mutant confers cross-resistance to daunomycin, quinidine, chloroquine, rhodamine 6G, and puromycin.	Daunorubicin	67-77	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	20-24	
8913437-1	1996	The effects of nine reversers of P-glycoprotein on the uptake of daunomycin into MDR1-transfected P388 cells were quantitatively determined in undiluted human or mouse plasma and compared with their effects when measurements are made in a conventional cell culture medium (RPMI 1640) containing only 10% serum.	Daunorubicin	65-75	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	81-85	
7659186-1	1995	A set of multidrug resistant (MDR) murine leukemia P388 sublines processing 30-50-fold mdr1 gene amplification was obtained as a result of experimental chemotherapy with rubomycin, ruboxyl, vinblastine, vincristine, or combination of rubomycin and vincristine.	Daunorubicin	170-179	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	30-33	
7659186-1	1995	A set of multidrug resistant (MDR) murine leukemia P388 sublines processing 30-50-fold mdr1 gene amplification was obtained as a result of experimental chemotherapy with rubomycin, ruboxyl, vinblastine, vincristine, or combination of rubomycin and vincristine.	Daunorubicin	234-243	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	30-33	
1868977-3	1991	Transgenic mice that express the MDR1 gene in their bone marrow have been developed, and because of this expression these mice are resistant to the bone marrow-suppressive effects of daunomycin, doxorubicin, taxol, and several other anticancer drugs.	Daunorubicin	183-193	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	33-37	
25695368-4	2015	Four compounds from this series were discovered as potent chemosensitizers for MDR1-G185 NIH-3T3 murine cells (3, 4, 6, and 7), showing higher efficacies than the classical P-glycoprotein inhibitor verapamil, a first-generation chemosensitizer, when reversing resistance to daunomycin and vinblastine at the lowest concentration tested of 1 muM.	Daunorubicin	274-284	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	79-83	
16542724-5	2006	Moreover, KT-5720 (at 5 mg/kg) sensitized the bone marrow of MDR1 transgenic mice model towards daunorubicin (at 8 mg/kg) without general toxic effects.	Daunorubicin	96-108	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	61-65