PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26002734-1	2015	Hepatic microsomal cytochrome P450 (CYP) enzymes have broad and overlapping substrate specificity and catalyze a variety of monooxygenase reactions, including aliphatic and aromatic hydroxylations, N-hydroxylations, oxygenations of heteroatoms (N, S, P and I), alkene and arene epoxidations, dehalogenations, dehydrogenations and N-, O- and S-dealkylations.	arene	272-277	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	19-34	
26002734-1	2015	Hepatic microsomal cytochrome P450 (CYP) enzymes have broad and overlapping substrate specificity and catalyze a variety of monooxygenase reactions, including aliphatic and aromatic hydroxylations, N-hydroxylations, oxygenations of heteroatoms (N, S, P and I), alkene and arene epoxidations, dehalogenations, dehydrogenations and N-, O- and S-dealkylations.	arene	272-277	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	36-39	
21539368-1	2011	Dopamine can be generated from tyramine via arene hydroxylation catalyzed by a cytochrome P450 enzyme (CYP2D6).	arene	44-49	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	79-94	
19480554-0	2009	Cytochrome P450-catalysed arene-epoxidation of the bioactive tea tree oil ingredient p-cymene: indication for the formation of a reactive allergenic intermediate?	arene	26-31	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	0-15	
19480554-7	2009	The enzymatic products of p-cymene resulted from catalysed enzymatic arene-epoxidation and hydroxylation reactions by the studied cytochrome P450 enzymes.	arene	69-74	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	130-145	
19480554-13	2009	The results also indicate that skin sensitization and irritation reactions not only can be explained by the frequently in literature reported auto-oxidation of tea tree resulting in bioactive oxidized products, but also now by the formation of epoxide intermediates resulting from catalysed arene-epoxidation reactions by selected human cytochrome P450 enzymes which are also located in different organs in humans.	arene	291-296	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	337-352