PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26499405-10	2015	Niclosamide also suppresses VEGF-induced angiogenesis in vivo.Niclosamide attenuated IKK-mediated activation of NF-kappaB pathway in TNFalpha-induced endothelial cells.	Niclosamide	0-11	tumor necrosis factor	Homo sapiens	133-141	
28529629-6	2017	Mechanistically, niclosamide abrogated the activation of the NF-kappaB pathway induced by tumor necrosis factor alpha (TNFalpha) in UM cells, while niclosamide elevated the levels of intracellullar and mitochondrial reactive oxygen species (ROS) in UM cells.	Niclosamide	17-28	tumor necrosis factor	Homo sapiens	90-117	
28529629-6	2017	Mechanistically, niclosamide abrogated the activation of the NF-kappaB pathway induced by tumor necrosis factor alpha (TNFalpha) in UM cells, while niclosamide elevated the levels of intracellullar and mitochondrial reactive oxygen species (ROS) in UM cells.	Niclosamide	17-28	tumor necrosis factor	Homo sapiens	119-127	
26499405-10	2015	Niclosamide also suppresses VEGF-induced angiogenesis in vivo.Niclosamide attenuated IKK-mediated activation of NF-kappaB pathway in TNFalpha-induced endothelial cells.	Niclosamide	62-73	tumor necrosis factor	Homo sapiens	133-141	
25708600-1	2015	OBJECTIVES: This study evaluated the anti-inflammatory effect of niclosamide in tumor necrosis factor (TNF)-alpha-stimulated human rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS) and inhibitory effects on migration and invasion in RA FLS and investigated the signal mechanism, and further explored the treatment activity of niclosamide on collagen-induced arthritis (CIA).	Niclosamide	65-76	tumor necrosis factor	Homo sapiens	80-113	
25708600-6	2015	RESULTS: Niclosamide reduced the secretion of IL-1beta, IL-6, IL-8, IL-17A and IFN-gamma from TNF-alpha-induced RA FLS in a dose-dependent manner.	Niclosamide	9-20	tumor necrosis factor	Homo sapiens	94-103	
25708600-8	2015	Niclosamide decreased the phosphorylation of c-Jun N-terminal kinase and ERK in TNF-alpha-stimulated RA FLS and blocked TNF-alpha-induced IKK, IkappaBalpha phosphorylation and translocation of p65.	Niclosamide	0-11	tumor necrosis factor	Homo sapiens	80-89	
25708600-8	2015	Niclosamide decreased the phosphorylation of c-Jun N-terminal kinase and ERK in TNF-alpha-stimulated RA FLS and blocked TNF-alpha-induced IKK, IkappaBalpha phosphorylation and translocation of p65.	Niclosamide	0-11	tumor necrosis factor	Homo sapiens	120-129