PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28575805-6 2017 Niclosamide potently inhibited cell proliferation and induced apoptosis in human papillary thyroid cancer cell lines TPC-1 and BCPAP, as well as anaplastic thyroid cancer cell line ACT-1. Niclosamide 0-11 two pore segment channel 1 Homo sapiens 117-122 28575805-7 2017 In addition, the occurrence of TPC-1 apoptosis was correlated with activation of Bax and cleaved caspases-3, and inhibition of Bcl-2 and the mitochondrial membrane potential (DeltaYm), indicating that niclosamide may induce apoptosis through a mitochondria-mediated intrinsic apoptotic pathway. Niclosamide 201-212 two pore segment channel 1 Homo sapiens 31-36 28575805-8 2017 Moreover, niclosamide markedly impaired TPC-1 cells and ACT-1 cells invasion. Niclosamide 10-21 two pore segment channel 1 Homo sapiens 40-45